Toluene-d8

Name: Toluene-d8
Brand: Vaqora Chemicals
SKU: VQ-041833

About Toluene-d8

Toluene-d8 (CAS 2037-26-5) is a stable isotope labelled analogue related to Toluene offered by Vaqora Chemicals. With the molecular formula C7H8, it has a molar mass of 100.19 g/mol. The IUPAC name is 1,2,3,4,5-pentadeuterio-6-(trideuteriomethyl)benzene. Alternative names: Benzene-d5, methyl-d3- and (2H8)Toluene.

It is supplied as a solid. Keep the vial tightly closed, protected from light and humidity, at the temperature stated on the Certificate of Analysis. Under GHS it is labelled “Danger”, so handle it with suitable PPE and consult the SDS.

Its mass shift relative to the unlabelled analyte makes it a dependable internal standard for LC-MS/MS assays, improving accuracy in bioanalysis, therapeutic drug monitoring and method validation. It is used across pharmaceutical manufacturing and academic and industrial research.

We offer Toluene-d8 in 10 mg, 25 mg, 50 mg and 100 mg packs with a batch-specific COA, and ship to customers worldwide.

Typical applications

LC-MS/MS internal standard
Bioanalytical quantitation
Pharmacokinetic studies

Industries

Related to Toluene

View every impurity, metabolite and intermediate we list for Toluene.

Toluene impurities

Grade guides

Specifications & identifiers

Chemical identifiers
Product name	Toluene-d8
Catalogue No.	VQ-041833
CAS Number	2037-26-5
IUPAC name	1,2,3,4,5-pentadeuterio-6-(trideuteriomethyl)benzene
Molecular formula	C₇H₈
Molecular weight	100.19 g/mol
Exact mass	100.1128
Grade	Reference Standard
HSN code	38229090
InChIKey	YXFVVABEGXRONW-JGUCLWPXSA-N
SMILES	[2H]C1=C(C(=C(C(=C1[2H])[2H])C([2H])([2H])[2H])[2H])[2H]
PubChem CID	74861

Physical properties
Physical form	Solid
LogP (XLogP3)	2.7
H-bond donors / acceptors	0 / 0
TPSA	0 Å²
Synonyms	Benzene-d5, methyl-d3-, (2H8)Toluene, Perdeuteriotoluene, Perdeuterated toluene, Deuterated toluene, Benzened5, methyld3, Benzene-D5-, methyl-D3-, Toluene-d8, 99.6 atom % D, Perdeuterotoluene

Safety & hazard information (GHS)

Flammable

Harmful / irritant

Health hazard

Signal word: Danger

Hazard statements

H225Highly flammable liquid and vapor
H304May be fatal if swallowed and enters airways
H315Causes skin irritation
H336May cause drowsiness or dizziness
H361Suspected of damaging fertility or the unborn child
H373May causes damage to organs through prolonged or repeated exposure

Precautionary statements: P203, P210, P233, P240, P241, P242, P243, P260, P261, P264, P271, P280, P301 + P316, P302 + P352, P303 + P361 + P353, P304 + P340, P318, P319, P321, P331, P332 + P317, P362 + P364, P370 + P378, P403 + P233

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Toluene-d8?

The CAS Registry Number of Toluene-d8 is 2037-26-5. It is also known as Benzene-d5, methyl-d3-, (2H8)Toluene, Perdeuteriotoluene.

What is the molecular formula and molecular weight of Toluene-d8?

Toluene-d8 has the molecular formula C7H8 and a molecular weight of 100.19 g/mol. Its IUPAC name is 1,2,3,4,5-pentadeuterio-6-(trideuteriomethyl)benzene.

What is Toluene-d8 used for?

Toluene-d8 is supplied as a characterised reference material related to Toluene. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Toluene-d8 can I order?

We supply Toluene-d8 in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Toluene-d8?

Yes. Every lot of Toluene-d8 is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Toluene-d8 be shipped internationally?

Yes. Toluene-d8 is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.