6a-Naltrexol

Name: 6a-Naltrexol
Brand: Vaqora Chemicals
SKU: VQ-044941

About 6a-Naltrexol

Listed under CAS 20410-98-4, 6a-Naltrexol is an impurity of Naltrexone available from Vaqora Chemicals. Formula C20H25NO4, molecular weight 343.4 g/mol. It is also known as 6α-Naltrexol or 6alpha-Naltrexol.

It is supplied as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. Under GHS it is labelled “Warning”, so handle it with suitable PPE and consult the SDS.

As a characterised impurity of Naltrexone, it is used for analytical method development, method validation (AMV) and routine quality-control testing, and it supports ANDA and DMF regulatory filings. Typical end-use sectors are pharmaceutical manufacturing and academic and industrial research.

Standard pack sizes are 10 mg, 25 mg, 50 mg and 100 mg, and every batch ships with a Certificate of Analysis (COA) and we export worldwide.

Typical applications

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Industries

Related to Naltrexone

View every impurity, metabolite and intermediate we list for Naltrexone.

Naltrexone impurities

Specifications & identifiers

Chemical identifiers
Product name	6a-Naltrexol
Catalogue No.	VQ-044941
CAS Number	20410-98-4
IUPAC name	(4R,4aS,7S,7aR,12bS)-3-(cyclopropylmethyl)-1,2,4,5,6,7,7a,13-octahydro-4,12-methanobenzofuro[3,2-e]isoquinoline-4a,7,9-triol
Molecular formula	C₂₀H₂₅NO₄
Molecular weight	343.4 g/mol
Exact mass	343.1784
Grade	Reference Standard
HSN code	38229090
InChIKey	JLVNEHKORQFVQJ-SBCNTATESA-N
SMILES	C1C[C@]2([C@H]3CC4=C5[C@@]2(CCN3CC6CC6)[C@H]([C@H]1O)OC5=C(C=C4)O)O
PubChem CID	16099582

Physical properties
Physical form	Solid
LogP (XLogP3)	-0.4
H-bond donors / acceptors	3 / 5
TPSA	73.2 Å²
Synonyms	6α-Naltrexol, 6alpha-Naltrexol, Naltrexone-6-alpha-ol, a-Naltrexo l, I+/-lpha-Naltrexol, 17-(Cyclopropylmethyl)-4,5a-epoxy-morphinan-3,6a,14-triol, (5a,6a)-17-(Cyclopropylmethyl)-4,5-epoxy-morphinan-3,6,14-triol, 17-(Cyclopropylmethyl)-5alpha-4,5-epoxymorphinan-3,6alpha,14-triol

Safety & hazard information (GHS)

Harmful / irritant

Signal word: Warning

Hazard statements

H302Harmful if swallowed
H332Harmful if inhaled

Precautionary statements: P261, P264, P270, P271, P301 + P317, P304 + P340, P317, P330, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of 6a-Naltrexol?

The CAS Registry Number of 6a-Naltrexol is 20410-98-4. It is also known as 6α-Naltrexol, 6alpha-Naltrexol, Naltrexone-6-alpha-ol.

What is the molecular formula and molecular weight of 6a-Naltrexol?

6a-Naltrexol has the molecular formula C20H25NO4 and a molecular weight of 343.4 g/mol. Its IUPAC name is (4R,4aS,7S,7aR,12bS)-3-(cyclopropylmethyl)-1,2,4,5,6,7,7a,13-octahydro-4,12-methanobenzofuro[3,2-e]isoquinoline-4a,7,9-triol.

What is 6a-Naltrexol used for?

6a-Naltrexol is supplied as a characterised reference material related to Naltrexone. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of 6a-Naltrexol can I order?

We supply 6a-Naltrexol in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with 6a-Naltrexol?

Yes. Every lot of 6a-Naltrexol is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can 6a-Naltrexol be shipped internationally?

Yes. 6a-Naltrexol is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.