Methylnaltrexone Bromide

Name: Methylnaltrexone Bromide
Brand: Vaqora Chemicals
SKU: VQ-038550

About Methylnaltrexone Bromide

Vaqora Chemicals supplies Methylnaltrexone Bromide, a high-purity reference standard of Naltrexone registered under CAS number 73232-52-7. Its molecular formula is C21H26BrNO4 and its molecular weight is 436.3 g/mol. Common synonyms include N-Methylnaltrexone Bromide and Naltrexone methobromide.

It is supplied as a solid. Store the standard in its sealed vial, protected from light and moisture, and follow the storage condition printed on the COA. The GHS classification uses the signal word “Danger”, so appropriate gloves, eye protection and ventilation are recommended.

Laboratories use this Naltrexone standard for identity and assay testing, system suitability checks and method validation supporting ANDA and DMF filings. Our customers for this product work in pharmaceutical manufacturing and academic and industrial research.

Available in 10 mg, 25 mg, 50 mg and 100 mg packs, Methylnaltrexone Bromide is dispatched with a Certificate of Analysis (COA) to destinations worldwide.

Typical applications

Identification & assay
Method development & validation
QC reference material
Fine chemical synthesis

Industries

Related to Naltrexone

View every impurity, metabolite and intermediate we list for Naltrexone.

Naltrexone impurities

Specifications & identifiers

Chemical identifiers
Product name	Methylnaltrexone Bromide
Catalogue No.	VQ-038550
CAS Number	73232-52-7
IUPAC name	(4R,4aS,7aR,12bS)-3-(cyclopropylmethyl)-4a,9-dihydroxy-3-methyl-2,4,5,6,7a,13-hexahydro-1H-4,12-methanobenzofuro[3,2-e]isoquinolin-3-ium-7-one bromide
Molecular formula	C₂₁H₂₆BrNO₄
Molecular weight	436.3 g/mol
Exact mass	435.1045
Grade	Reference Standard
HSN code	38229090
InChIKey	IFGIYSGOEZJNBE-KNLJMPJLSA-N
SMILES	C[N+]1(CC[C@]23[C@@H]4C(=O)CC[C@]2([C@H]1CC5=C3C(=C(C=C5)O)O4)O)CC6CC6.[Br-]
PubChem CID	5361917

Physical properties
Physical form	Solid
H-bond donors / acceptors	2 / 5
TPSA	66.8 Å²
Synonyms	N-Methylnaltrexone Bromide, Naltrexone methobromide, MRZ-2663BR, MOA-728, bromuro de metilnaltrexona, bromure de methylnaltrexone, methylnaltrexoni bromidum, N-Methyl Naltrexone Bromide, MRZ 2663BR, Naltrexone Methyl Bromide

Safety & hazard information (GHS)

Toxic

Harmful / irritant

Health hazard

Environmental hazard

Signal word: Danger

Hazard statements

H301Toxic if swallowed
H302Harmful if swallowed
H312Harmful in contact with skin
H317May cause an allergic skin reaction
H332Harmful if inhaled
H334May cause allergy or asthma symptoms or breathing difficulties if inhaled
H400Very toxic to aquatic life

Precautionary statements: P233, P260, P261, P264, P270, P271, P272, P273, P280, P284, P301 + P316, P301 + P317, P302 + P352, P304 + P340, P317, P321, P330, P333 + P317, P342 + P316, P362 + P364, P391, P403, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Methylnaltrexone Bromide?

The CAS Registry Number of Methylnaltrexone Bromide is 73232-52-7. It is also known as N-Methylnaltrexone Bromide, Naltrexone methobromide, MRZ-2663BR.

What is the molecular formula and molecular weight of Methylnaltrexone Bromide?

Methylnaltrexone Bromide has the molecular formula C21H26BrNO4 and a molecular weight of 436.3 g/mol. Its IUPAC name is (4R,4aS,7aR,12bS)-3-(cyclopropylmethyl)-4a,9-dihydroxy-3-methyl-2,4,5,6,7a,13-hexahydro-1H-4,12-methanobenzofuro[3,2-e]isoquinolin-3-ium-7-one bromide.

What is Methylnaltrexone Bromide used for?

Methylnaltrexone Bromide is supplied as a characterised reference material related to Naltrexone. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Methylnaltrexone Bromide can I order?

We supply Methylnaltrexone Bromide in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Methylnaltrexone Bromide?

Yes. Every lot of Methylnaltrexone Bromide is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Methylnaltrexone Bromide be shipped internationally?

Yes. Methylnaltrexone Bromide is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.