Ibrutinib Impurity D

Name: Ibrutinib Impurity D
Brand: Vaqora Chemicals
SKU: VQ-005074

About Ibrutinib Impurity D

Ibrutinib Impurity D is an impurity of Ibrutinib carrying the CAS registry number 2052279-48-6 at a purity of 94%. With the molecular formula C28H28N6O4, it has a molar mass of 512.6 g/mol. Its systematic (IUPAC) name is 4-[(3R)-3-[4-amino-3-(4-phenoxyphenyl)pyrazolo[3,4-d]pyrimidin-1-yl]piperidine-1-carbonyl]pent-4-enoic acid. Alternative names: Ibrutinib Impurity 38.

The product is provided as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. Handle it with standard laboratory precautions and appropriate personal protective equipment.

As a characterised impurity of Ibrutinib, it is used for analytical method development, method validation (AMV) and routine quality-control testing, and it supports ANDA and DMF regulatory filings. Buyers come mainly from pharmaceutical manufacturing and academic and industrial research.

Vaqora Chemicals supplies Ibrutinib Impurity D in 10 mg packs, each shipped with a Certificate of Analysis (COA), and exports worldwide. This item is currently in stock for prompt dispatch.

Typical applications

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Industries

Related to Ibrutinib

View every impurity, metabolite and intermediate we list for Ibrutinib.

Ibrutinib impurities

Specifications & identifiers

Chemical identifiers
Product name	Ibrutinib Impurity D
Catalogue No.	VQ-005074
CAS Number	2052279-48-6
IUPAC name	4-[(3R)-3-[4-amino-3-(4-phenoxyphenyl)pyrazolo[3,4-d]pyrimidin-1-yl]piperidine-1-carbonyl]pent-4-enoic acid
Molecular formula	C₂₈H₂₈N₆O₄
Molecular weight	512.6 g/mol
Exact mass	512.2172
Grade	Reference Standard
Purity / assay	94%
HSN code	38229090
InChIKey	AECOEEIYLWEDRG-HXUWFJFHSA-N
SMILES	C=C(CCC(=O)O)C(=O)N1CCC[C@H](C1)N2C3=NC=NC(=C3C(=N2)C4=CC=C(C=C4)OC5=CC=CC=C5)N
PubChem CID	163202514

Physical properties
Physical form	Solid
LogP (XLogP3)	3.3
H-bond donors / acceptors	2 / 8
TPSA	136 Å²

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Ibrutinib Impurity D?

The CAS Registry Number of Ibrutinib Impurity D is 2052279-48-6. It is also known as Ibrutinib Impurity 38.

What is the molecular formula and molecular weight of Ibrutinib Impurity D?

Ibrutinib Impurity D has the molecular formula C28H28N6O4 and a molecular weight of 512.6 g/mol. Its IUPAC name is 4-[(3R)-3-[4-amino-3-(4-phenoxyphenyl)pyrazolo[3,4-d]pyrimidin-1-yl]piperidine-1-carbonyl]pent-4-enoic acid.

What is Ibrutinib Impurity D used for?

Ibrutinib Impurity D is supplied as a characterised reference material related to Ibrutinib. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Ibrutinib Impurity D can I order?

We supply Ibrutinib Impurity D in Reference Standard (94%) grade, in 10 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Ibrutinib Impurity D?

Yes. Every lot of Ibrutinib Impurity D is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Ibrutinib Impurity D be shipped internationally?

Yes. We export Ibrutinib Impurity D worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.