- CAS
- 1173825-84-7
- Formula
- C32H27Cl6N5O5
- MW
- 774.3 g/mol
6-O-Methylguanine
Synonyms: 6-Methoxyguanine · O6-Methylguanine · O-(6)-Methylguanine · 1H-Purin-2-amine, 6-methoxy-
6-O-Methylguanine (CAS 20535-83-5) – Nelarabine impurity standard. C6H7N5O, MW 165.15. Request a quote: COA, bulk packs and worldwide export.
About 6-O-Methylguanine
6-O-Methylguanine (CAS 20535-83-5) is an impurity of Nelarabine offered by Vaqora Chemicals. Formula C6H7N5O, molecular weight 165.15 g/mol. The IUPAC name is 6-methoxy-7H-purin-2-amine. Alternative names: 6-Methoxyguanine and O6-Methylguanine.
It is supplied as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. Under GHS it is labelled “Danger”, so handle it with suitable PPE and consult the SDS.
Pharmaceutical QC and development laboratories use this impurity standard of Nelarabine to develop and validate HPLC methods, to set specification limits and to document impurity profiles in ANDA and DMF submissions. Typical end-use sectors are pharmaceutical manufacturing and academic and industrial research.
We offer 6-O-Methylguanine in 10 mg, 25 mg, 50 mg and 100 mg packs with a batch-specific COA, and ship to customers worldwide.
Typical applications
- Analytical method development
- Method validation (AMV)
- QC release testing
- ANDA / DMF filings
Industries
View every impurity, metabolite and intermediate we list for Nelarabine.
Nelarabine impuritiesSpecifications & identifiers
| Product name | 6-O-Methylguanine |
|---|---|
| Catalogue No. | VQ-027232 |
| CAS Number | 20535-83-5 |
| IUPAC name | 6-methoxy-7H-purin-2-amine |
| Molecular formula | C6H7N5O |
| Molecular weight | 165.15 g/mol |
| Exact mass | 165.0651 |
| Grade | Reference Standard |
| HSN code | 38229090 |
| InChIKey | BXJHWYVXLGLDMZ-UHFFFAOYSA-N |
| SMILES | COC1=NC(=NC2=C1NC=N2)N |
| PubChem CID | 65275 |
| Physical form | Solid |
|---|---|
| LogP (XLogP3) | -0.2 |
| H-bond donors / acceptors | 2 / 5 |
| TPSA | 89.7 Ų |
| Synonyms | 6-Methoxyguanine, O6-Methylguanine, O-(6)-Methylguanine, 1H-Purin-2-amine, 6-methoxy-, Purine, 2-amino-6-methoxy-, 6-Methoxy-1H-purine-2-amine, O(sup 6)-Methylguanine, O(6)-methylguanine, 6-methylguanine, Purine, 2-amino-6-methoxy-(8CI), 2-Amino-6-methoxypurine, 6-methoxy-9H-purin-2-amine |
Safety & hazard information (GHS)
Signal word: Danger
Hazard statements
H302Harmful if swallowedH312Harmful in contact with skinH315Causes skin irritationH318Causes serious eye damageH319Causes serious eye irritationH332Harmful if inhaledH335May cause respiratory irritationH341Suspected of causing genetic defectsH361Suspected of damaging fertility or the unborn child
Precautionary statements: P203, P261, P264, P264 + P265, P270, P271, P280, P301 + P317, P302 + P352, P304 + P340, P305 + P351 + P338, P305 + P354 + P338, P317, P318, P319, P321, P330, P332 + P317, P337 + P317, P362 + P364, P403 + P233, P405, P501
Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.
Documents
Frequently asked questions
What is the CAS number of 6-O-Methylguanine?
The CAS Registry Number of 6-O-Methylguanine is 20535-83-5. It is also known as 6-Methoxyguanine, O6-Methylguanine, O-(6)-Methylguanine.
What is the molecular formula and molecular weight of 6-O-Methylguanine?
6-O-Methylguanine has the molecular formula C6H7N5O and a molecular weight of 165.15 g/mol. Its IUPAC name is 6-methoxy-7H-purin-2-amine.
What is 6-O-Methylguanine used for?
6-O-Methylguanine is supplied as a characterised reference material related to Nelarabine. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.
Which grade and pack sizes of 6-O-Methylguanine can I order?
We supply 6-O-Methylguanine in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.
Do you provide a COA and SDS with 6-O-Methylguanine?
Yes. Every lot of 6-O-Methylguanine is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.
Can 6-O-Methylguanine be shipped internationally?
Yes. 6-O-Methylguanine is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.
Enquire about 6-O-Methylguanine
We reply within one business day with price, pack options, lead time and documentation.