8-Hydroxy Efavirenz

Name: 8-Hydroxy Efavirenz
Brand: Vaqora Chemicals
SKU: VQ-030391

About 8-Hydroxy Efavirenz

8-Hydroxy Efavirenz (CAS 205754-33-2) is a metabolite or degradation product of Efavirenz offered by Vaqora Chemicals. With the molecular formula C14H9ClF3NO3, it has a molar mass of 331.67 g/mol. Its systematic (IUPAC) name is (4S)-6-chloro-4-(2-cyclopropylethynyl)-8-hydroxy-4-(trifluoromethyl)-1H-3,1-benzoxazin-2-one. It is also known as 8-OH efavirenz or 8-hydroxy EFV.

It is supplied as a solid. Keep the vial tightly closed, protected from light and humidity, at the temperature stated on the Certificate of Analysis. Handle it with standard laboratory precautions and appropriate personal protective equipment.

Analytical teams use this compound to identify metabolites and degradants of Efavirenz, to validate stability-indicating methods (AMV) and to support QC and regulatory filings. Our customers for this product work in pharmaceutical manufacturing and academic and industrial research.

Available in 10 mg, 25 mg, 50 mg and 100 mg packs, 8-Hydroxy Efavirenz is dispatched with a Certificate of Analysis (COA) to destinations worldwide.

Typical applications

Metabolite identification
Stability-indicating methods
Impurity profiling

Industries

Related to Efavirenz

View every impurity, metabolite and intermediate we list for Efavirenz.

Efavirenz impurities

Specifications & identifiers

Chemical identifiers
Product name	8-Hydroxy Efavirenz
Catalogue No.	VQ-030391
CAS Number	205754-33-2
IUPAC name	(4S)-6-chloro-4-(2-cyclopropylethynyl)-8-hydroxy-4-(trifluoromethyl)-1H-3,1-benzoxazin-2-one
Molecular formula	C₁₄H₉ClF₃NO₃
Molecular weight	331.67 g/mol
Exact mass	331.0223
Grade	Reference Standard
HSN code	38229090
InChIKey	OOVOMPCQLMFEDT-ZDUSSCGKSA-N
SMILES	C1CC1C#C[C@]2(C3=C(C(=CC(=C3)Cl)O)NC(=O)O2)C(F)(F)F
PubChem CID	487643

Physical properties
Physical form	Solid
LogP (XLogP3)	3.7
H-bond donors / acceptors	2 / 6
TPSA	58.6 Å²
Synonyms	8-OH efavirenz, 8-hydroxy EFV, 8-OH EFV, 8-hydroxy-efavirenz-glucuronide, (4S)-6-Chloro-4-(cyclopropylethynyl)-4-(trifluoromethyl)-4H-3,1-benzoxazine-2,8-diol, 6-Chloro-4-(cyclopropylethynyl)-4-(trifluoromethyl)-4H-3,1-benzoxazine-2,8-diol

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of 8-Hydroxy Efavirenz?

The CAS Registry Number of 8-Hydroxy Efavirenz is 205754-33-2. It is also known as 8-OH efavirenz, 8-hydroxy EFV, 8-OH EFV.

What is the molecular formula and molecular weight of 8-Hydroxy Efavirenz?

8-Hydroxy Efavirenz has the molecular formula C14H9ClF3NO3 and a molecular weight of 331.67 g/mol. Its IUPAC name is (4S)-6-chloro-4-(2-cyclopropylethynyl)-8-hydroxy-4-(trifluoromethyl)-1H-3,1-benzoxazin-2-one.

What is 8-Hydroxy Efavirenz used for?

8-Hydroxy Efavirenz is supplied as a characterised reference material related to Efavirenz. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of 8-Hydroxy Efavirenz can I order?

We supply 8-Hydroxy Efavirenz in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with 8-Hydroxy Efavirenz?

Yes. Every lot of 8-Hydroxy Efavirenz is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can 8-Hydroxy Efavirenz be shipped internationally?

Yes. We export 8-Hydroxy Efavirenz worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.