Methylphenidate EP Impurity B

About Methylphenidate EP Impurity B

Methylphenidate EP Impurity B is a pharmacopeial impurity of Methylphenidate carrying the CAS registry number 20748-12-3. The compound has the formula C14H19NO2, corresponding to a molecular weight of 233.31 g/mol. The IUPAC name is methyl (2S)-2-phenyl-2-[(2R)-piperidin-2-yl]acetate. Common synonyms include Methylphenidate Hydrochloride - Impurity B and methyl (S)-phenyl[(R)-piperidin-2-yl]acetate.

The product is provided as a solid. Keep the vial tightly closed, protected from light and humidity, at the temperature stated on the Certificate of Analysis. Handle it with standard laboratory precautions and appropriate personal protective equipment.

This Methylphenidate impurity supports analytical method development and validation (AMV), batch release testing and the impurity sections of ANDA and DMF filings. Buyers come mainly from pharmaceutical manufacturing and academic and industrial research.

Available in 10 mg, 25 mg, 50 mg and 100 mg packs, Methylphenidate EP Impurity B is dispatched with a Certificate of Analysis (COA) to destinations worldwide.

Typical applications

Pharmacopeial method verification
Impurity profiling
QC release testing
ANDA / DMF filings

Industries

Related to Methylphenidate

View every impurity, metabolite and intermediate we list for Methylphenidate.

Methylphenidate impurities

Grade guides

Specifications & identifiers

Chemical identifiers
Product name	Methylphenidate EP Impurity B
Catalogue No.	VQ-035450
CAS Number	20748-12-3
IUPAC name	methyl (2S)-2-phenyl-2-[(2R)-piperidin-2-yl]acetate
Molecular formula	C₁₄H₁₉NO₂
Molecular weight	233.31 g/mol
Exact mass	233.1416
Grade	Reference Standard
HSN code	38229090
InChIKey	DUGOZIWVEXMGBE-OLZOCXBDSA-N
SMILES	COC(=O)[C@H]([C@H]1CCCCN1)C2=CC=CC=C2
PubChem CID	6101852

Physical properties
Physical form	Solid
LogP (XLogP3)	0.2
H-bond donors / acceptors	1 / 3
TPSA	38.3 Å²
Synonyms	Methylphenidate Hydrochloride - Impurity B, methyl (S)-phenyl[(R)-piperidin-2-yl]acetate, methyl (2S)-phenyl[(2R)-piperidin-2-yl]acetate, methyl (S)-phenyl((R)-piperidin-2-yl)acetate, methyl (2S)-phenyl((2R)-piperidin-2-yl)acetate, Erythro-meridil, (+/-)-Erythro-methylphenidate, Methylphenidate, (+/-)-erythro, Erythro-methyl 2-phenyl-2-(2-piperidyl)acetate, threo-Methylphenidate, 2-Piperidineacetic acid, alpha-phenyl-, methyl ester, (R,S)-(+/-)-, dl-threo-Methylphenidate

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Methylphenidate EP Impurity B?

The CAS Registry Number of Methylphenidate EP Impurity B is 20748-12-3. It is also known as Methylphenidate Hydrochloride - Impurity B, methyl (S)-phenyl[(R)-piperidin-2-yl]acetate, methyl (2S)-phenyl[(2R)-piperidin-2-yl]acetate.

What is the molecular formula and molecular weight of Methylphenidate EP Impurity B?

Methylphenidate EP Impurity B has the molecular formula C14H19NO2 and a molecular weight of 233.31 g/mol. Its IUPAC name is methyl (2S)-2-phenyl-2-[(2R)-piperidin-2-yl]acetate.

What is Methylphenidate EP Impurity B used for?

Methylphenidate EP Impurity B is supplied as a characterised reference material related to Methylphenidate. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Methylphenidate EP Impurity B can I order?

We supply Methylphenidate EP Impurity B in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Methylphenidate EP Impurity B?

Yes. Every lot of Methylphenidate EP Impurity B is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Methylphenidate EP Impurity B be shipped internationally?

Yes. We export Methylphenidate EP Impurity B worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.