Temozolomide-d3

About Temozolomide-d3

Temozolomide-d3 is a stable isotope labelled analogue related to Temozolomide carrying the CAS registry number 208107-14-6. Formula C6H6N6O2, molecular weight 197.17 g/mol. The IUPAC name is 4-oxo-3-(trideuteriomethyl)imidazo[5,1-d][1,2,3,5]tetrazine-8-carboxamide. Alternative names: TMID-1105.

The product is provided as a solid. Store the standard in its sealed vial, protected from light and moisture, and follow the storage condition printed on the COA. The GHS classification uses the signal word “Danger”, so appropriate gloves, eye protection and ventilation are recommended.

Its mass shift relative to the unlabelled analyte makes it a dependable internal standard for LC-MS/MS assays, improving accuracy in bioanalysis, therapeutic drug monitoring and method validation. Buyers come mainly from pharmaceutical manufacturing and academic and industrial research.

We offer Temozolomide-d3 in 10 mg, 25 mg, 50 mg and 100 mg packs with a batch-specific COA, and ship to customers worldwide.

Typical applications

LC-MS/MS internal standard
Bioanalytical quantitation
Pharmacokinetic studies

Industries

Related to Temozolomide

View every impurity, metabolite and intermediate we list for Temozolomide.

Temozolomide impurities

Grade guides

Specifications & identifiers

Chemical identifiers
Product name	Temozolomide-d3
Catalogue No.	VQ-042407
CAS Number	208107-14-6
IUPAC name	4-oxo-3-(trideuteriomethyl)imidazo[5,1-d][1,2,3,5]tetrazine-8-carboxamide
Molecular formula	C₆H₆N₆O₂
Molecular weight	197.17 g/mol
Exact mass	197.0741
Grade	Reference Standard
HSN code	38229090
InChIKey	BPEGJWRSRHCHSN-FIBGUPNXSA-N
SMILES	[2H]C([2H])([2H])N1C(=O)N2C=NC(=C2N=N1)C(=O)N
PubChem CID	10488155

Physical properties
Physical form	Solid
LogP (XLogP3)	-1.1
H-bond donors / acceptors	1 / 5
TPSA	106 Å²

Safety & hazard information (GHS)

Harmful / irritant

Health hazard

Signal word: Danger

Hazard statements

H302Harmful if swallowed
H340May cause genetic defects
H350May cause cancer
H360May damage fertility or the unborn child
H412Harmful to aquatic life with long lasting effects

Precautionary statements: P203, P264, P270, P273, P280, P301 + P317, P318, P330, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Temozolomide-d3?

The CAS Registry Number of Temozolomide-d3 is 208107-14-6. It is also known as TMID-1105, 3-(~2~H_3_)Methyl-4-oxo-3,4-dihydroimidazo[5,1-d][1,2,3,5]tetrazine-8-carboxamide, 3-(2H3)methyl-4-oxo-3,4-dihydroimidazo[5,1-d][1,2,3,5]tetrazine-8-carboxamide.

What is the molecular formula and molecular weight of Temozolomide-d3?

Temozolomide-d3 has the molecular formula C6H6N6O2 and a molecular weight of 197.17 g/mol. Its IUPAC name is 4-oxo-3-(trideuteriomethyl)imidazo[5,1-d][1,2,3,5]tetrazine-8-carboxamide.

What is Temozolomide-d3 used for?

Temozolomide-d3 is supplied as a characterised reference material related to Temozolomide. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Temozolomide-d3 can I order?

We supply Temozolomide-d3 in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Temozolomide-d3?

Yes. Every lot of Temozolomide-d3 is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Temozolomide-d3 be shipped internationally?

Yes. Temozolomide-d3 is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.