Topiramate EP Impurity A

Name: Topiramate EP Impurity A
Brand: Vaqora Chemicals
SKU: VQ-028460

About Topiramate EP Impurity A

Topiramate EP Impurity A (CAS 20880-92-6) is a pharmacopeial impurity of Topiramate offered by Vaqora Chemicals. Its molecular formula is C12H20O6 and its molecular weight is 260.28 g/mol. The IUPAC name is [(1R,2S,6S,9R)-4,4,11,11-tetramethyl-3,5,7,10,12-pentaoxatricyclo[7.3.0.02,6]dodecan-6-yl]methanol. Common synonyms include Topiramate - Impurity A and Topiramate Related Compound A.

It is supplied as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. Under GHS it is labelled “Warning”, so handle it with suitable PPE and consult the SDS.

Pharmaceutical QC and development laboratories use this impurity standard of Topiramate to develop and validate HPLC methods, to set specification limits and to document impurity profiles in ANDA and DMF submissions. Our customers for this product work in pharmaceutical manufacturing and academic and industrial research.

Available in 10 mg, 25 mg, 50 mg and 100 mg packs, Topiramate EP Impurity A is dispatched with a Certificate of Analysis (COA) to destinations worldwide.

Typical applications

Pharmacopeial method verification
Impurity profiling
QC release testing
ANDA / DMF filings

Industries

Related to Topiramate

View every impurity, metabolite and intermediate we list for Topiramate.

Topiramate impurities

Grade guides

Specifications & identifiers

Chemical identifiers
Product name	Topiramate EP Impurity A
Catalogue No.	VQ-028460
CAS Number	20880-92-6
IUPAC name	[(1R,2S,6S,9R)-4,4,11,11-tetramethyl-3,5,7,10,12-pentaoxatricyclo[7.3.0.02,6]dodecan-6-yl]methanol
Molecular formula	C₁₂H₂₀O₆
Molecular weight	260.28 g/mol
Exact mass	260.126
Grade	Reference Standard
HSN code	38229090
InChIKey	PSSHGMIAIUYOJF-XBWDGYHZSA-N
SMILES	CC1(O[C@@H]2CO[C@@]3([C@H]([C@@H]2O1)OC(O3)(C)C)CO)C
PubChem CID	10244345

Physical properties
Physical form	Solid
LogP (XLogP3)	-0.3
H-bond donors / acceptors	1 / 6
TPSA	66.4 Å²
Synonyms	2,3:4,5-Di-O-isopropylidene-Beta-D-fructopyranose, Topiramate - Impurity A, Topiramate Related Compound A, D-Fructopyranose diacetonide, Diacetone-D-fructose, beta-D-Fructopyranose, 2,3:4,5-bis-O-(1-methylethylidene)-, .beta.-D-Fructopyranose, 2,3:4,5-bis-O-(1-methylethylidene)-, Diacetone-beta-D-fructose, Diacetonefructose, 2,3:4,5-Bis-O-(1-methylethylidene)-beta-D-fructopyranose, Diacetone-ss-D-fructose, Diacetone-

Safety & hazard information (GHS)

Harmful / irritant

Signal word: Warning

Hazard statements

H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation

Precautionary statements: P261, P264, P264 + P265, P271, P280, P302 + P352, P304 + P340, P305 + P351 + P338, P319, P321, P332 + P317, P337 + P317, P362 + P364, P403 + P233, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Topiramate EP Impurity A?

The CAS Registry Number of Topiramate EP Impurity A is 20880-92-6. It is also known as 2,3:4,5-Di-O-isopropylidene-Beta-D-fructopyranose, Topiramate - Impurity A, Topiramate Related Compound A.

What is the molecular formula and molecular weight of Topiramate EP Impurity A?

Topiramate EP Impurity A has the molecular formula C12H20O6 and a molecular weight of 260.28 g/mol. Its IUPAC name is [(1R,2S,6S,9R)-4,4,11,11-tetramethyl-3,5,7,10,12-pentaoxatricyclo[7.3.0.02,6]dodecan-6-yl]methanol.

What is Topiramate EP Impurity A used for?

Topiramate EP Impurity A is supplied as a characterised reference material related to Topiramate. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Topiramate EP Impurity A can I order?

We supply Topiramate EP Impurity A in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Topiramate EP Impurity A?

Yes. Every lot of Topiramate EP Impurity A is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Topiramate EP Impurity A be shipped internationally?

Yes. Topiramate EP Impurity A is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.