3-((3R,4R)-3-(((5S,6R)-5,6-Dihydroxy-6,7-dihy… 2101951-13-5

Name: 3-((3R,4R)-3-(((5S,6R)-5,6-Dihydroxy-6,7-dihydro-5H-pyrrolo[2,3-d]pyrimidin-4-yl)(methyl)amino)-4-methylpiperidin-1-yl)-3-oxopropanenitrile
Brand: Vaqora Chemicals
SKU: VQ-034312

About 3-((3R,4R)-3-(((5S,6R)-5,6-Dihydroxy-6,7-dihydro-5H-pyrrolo[2,3-d]pyrimidin-4-yl)(methyl)amino)-4-methylpiperidin-1-yl)-3-oxopropanenitrile

Listed under CAS 2101951-13-5, 3-((3R,4R)-3-(((5S,6R)-5,6-Dihydroxy-6,7-dihydro-5H-pyrrolo[2,3-d]pyrimidin-4-yl)(methyl)amino)-4-methylpiperidin-1-yl)-3-oxopropanenitrile is an impurity of Tofacitinib available from Vaqora Chemicals. Formula C16H22N6O3, molecular weight 346.38 g/mol.

The product is provided as a solid. Store the standard in its sealed vial, protected from light and moisture, and follow the storage condition printed on the COA. Handle it with standard laboratory precautions and appropriate personal protective equipment.

As a characterised impurity of Tofacitinib, it is used for analytical method development, method validation (AMV) and routine quality-control testing, and it supports ANDA and DMF regulatory filings. It is used across pharmaceutical manufacturing and academic and industrial research.

We offer 3-((3R,4R)-3-(((5S,6R)-5,6-Dihydroxy-6,7-dihydro-5H-pyrrolo[2,3-d]pyrimidin-4-yl)(methyl)amino)-4-methylpiperidin-1-yl)-3-oxopropanenitrile in 10 mg, 25 mg, 50 mg and 100 mg packs with a batch-specific COA, and ship to customers worldwide. SDS and detailed specification sheets can be requested with your quotation.

Typical applications

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Industries

Related to Tofacitinib

View every impurity, metabolite and intermediate we list for Tofacitinib.

Tofacitinib impurities

Specifications & identifiers

Chemical identifiers
Product name	3-((3R,4R)-3-(((5S,6R)-5,6-Dihydroxy-6,7-dihydro-5H-pyrrolo[2,3-d]pyrimidin-4-yl)(methyl)amino)-4-methylpiperidin-1-yl)-3-oxopropanenitrile
Catalogue No.	VQ-034312
CAS Number	2101951-13-5
IUPAC name	3-[(3R,4R)-3-[[(5S,6R)-5,6-dihydroxy-6,7-dihydro-5H-pyrrolo[2,3-d]pyrimidin-4-yl]-methylamino]-4-methylpiperidin-1-yl]-3-oxopropanenitrile
Molecular formula	C₁₆H₂₂N₆O₃
Molecular weight	346.38 g/mol
Exact mass	346.1753
Grade	Reference Standard
HSN code	38229090
InChIKey	OTCVGLUFZKDIFV-SUJFGCQRSA-N
SMILES	C[C@@H]1CCN(C[C@@H]1N(C)C2=NC=NC3=C2[C@@H]([C@H](N3)O)O)C(=O)CC#N
PubChem CID	177847475

Physical properties
Physical form	Solid
LogP (XLogP3)	-0.2
H-bond donors / acceptors	3 / 8
TPSA	126 Å²

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of 3-((3R,4R)-3-(((5S,6R)-5,6-Dihydroxy-6,7-dihydro-5H-pyrrolo[2,3-d]pyrimidin-4-yl)(methyl)amino)-4-methylpiperidin-1-yl)-3-oxopropanenitrile?

The CAS Registry Number of 3-((3R,4R)-3-(((5S,6R)-5,6-Dihydroxy-6,7-dihydro-5H-pyrrolo[2,3-d]pyrimidin-4-yl)(methyl)amino)-4-methylpiperidin-1-yl)-3-oxopropanenitrile is 2101951-13-5.

What is the molecular formula and molecular weight of 3-((3R,4R)-3-(((5S,6R)-5,6-Dihydroxy-6,7-dihydro-5H-pyrrolo[2,3-d]pyrimidin-4-yl)(methyl)amino)-4-methylpiperidin-1-yl)-3-oxopropanenitrile?

3-((3R,4R)-3-(((5S,6R)-5,6-Dihydroxy-6,7-dihydro-5H-pyrrolo[2,3-d]pyrimidin-4-yl)(methyl)amino)-4-methylpiperidin-1-yl)-3-oxopropanenitrile has the molecular formula C16H22N6O3 and a molecular weight of 346.38 g/mol. Its IUPAC name is 3-[(3R,4R)-3-[[(5S,6R)-5,6-dihydroxy-6,7-dihydro-5H-pyrrolo[2,3-d]pyrimidin-4-yl]-methylamino]-4-methylpiperidin-1-yl]-3-oxopropanenitrile.

What is 3-((3R,4R)-3-(((5S,6R)-5,6-Dihydroxy-6,7-dihydro-5H-pyrrolo[2,3-d]pyrimidin-4-yl)(methyl)amino)-4-methylpiperidin-1-yl)-3-oxopropanenitrile used for?

3-((3R,4R)-3-(((5S,6R)-5,6-Dihydroxy-6,7-dihydro-5H-pyrrolo[2,3-d]pyrimidin-4-yl)(methyl)amino)-4-methylpiperidin-1-yl)-3-oxopropanenitrile is supplied as a characterised reference material related to Tofacitinib. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of 3-((3R,4R)-3-(((5S,6R)-5,6-Dihydroxy-6,7-dihydro-5H-pyrrolo[2,3-d]pyrimidin-4-yl)(methyl)amino)-4-methylpiperidin-1-yl)-3-oxopropanenitrile can I order?

We supply 3-((3R,4R)-3-(((5S,6R)-5,6-Dihydroxy-6,7-dihydro-5H-pyrrolo[2,3-d]pyrimidin-4-yl)(methyl)amino)-4-methylpiperidin-1-yl)-3-oxopropanenitrile in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with 3-((3R,4R)-3-(((5S,6R)-5,6-Dihydroxy-6,7-dihydro-5H-pyrrolo[2,3-d]pyrimidin-4-yl)(methyl)amino)-4-methylpiperidin-1-yl)-3-oxopropanenitrile?

Yes. Every lot of 3-((3R,4R)-3-(((5S,6R)-5,6-Dihydroxy-6,7-dihydro-5H-pyrrolo[2,3-d]pyrimidin-4-yl)(methyl)amino)-4-methylpiperidin-1-yl)-3-oxopropanenitrile is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can 3-((3R,4R)-3-(((5S,6R)-5,6-Dihydroxy-6,7-dihydro-5H-pyrrolo[2,3-d]pyrimidin-4-yl)(methyl)amino)-4-methylpiperidin-1-yl)-3-oxopropanenitrile be shipped internationally?

Yes. We export 3-((3R,4R)-3-(((5S,6R)-5,6-Dihydroxy-6,7-dihydro-5H-pyrrolo[2,3-d]pyrimidin-4-yl)(methyl)amino)-4-methylpiperidin-1-yl)-3-oxopropanenitrile worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.