4-((2,4-Diaminopyrimidin-5-yl)methyl)-2,6-dim… 21253-58-7

About 4-((2,4-Diaminopyrimidin-5-yl)methyl)-2,6-dimethoxyphenol

4-((2,4-Diaminopyrimidin-5-yl)methyl)-2,6-dimethoxyphenol is an impurity of Trimethoprim carrying the CAS registry number 21253-58-7. The compound has the formula C13H16N4O3, corresponding to a molecular weight of 276.29 g/mol. Alternative names: 4-Demethyltrimethoprim and 4'-Hydroxytrimethoprim.

The product is provided as a solid. Keep the vial tightly closed, protected from light and humidity, at the temperature stated on the Certificate of Analysis. Good laboratory practice and suitable PPE are recommended during handling.

As a characterised impurity of Trimethoprim, it is used for analytical method development, method validation (AMV) and routine quality-control testing, and it supports ANDA and DMF regulatory filings. Buyers come mainly from pharmaceutical manufacturing and academic and industrial research.

We offer 4-((2,4-Diaminopyrimidin-5-yl)methyl)-2,6-dimethoxyphenol in 10 mg, 25 mg, 50 mg and 100 mg packs with a batch-specific COA, and ship to customers worldwide.

Typical applications

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Industries

Related to Trimethoprim

View every impurity, metabolite and intermediate we list for Trimethoprim.

Trimethoprim impurities

Specifications & identifiers

Chemical identifiers
Product name	4-((2,4-Diaminopyrimidin-5-yl)methyl)-2,6-dimethoxyphenol
Catalogue No.	VQ-034445
CAS Number	21253-58-7
IUPAC name	4-[(2,4-diaminopyrimidin-5-yl)methyl]-2,6-dimethoxyphenol
Molecular formula	C₁₃H₁₆N₄O₃
Molecular weight	276.29 g/mol
Exact mass	276.1222
Grade	Reference Standard
HSN code	38229090
InChIKey	HPOCGNHBIFZCAN-UHFFFAOYSA-N
SMILES	COC1=CC(=CC(=C1O)OC)CC2=CN=C(N=C2N)N
PubChem CID	10423570

Physical properties
Physical form	Solid
LogP (XLogP3)	0.4
H-bond donors / acceptors	3 / 7
TPSA	117 Å²
Synonyms	4-Demethyltrimethoprim, 4-[(2,4-Diamino-5-pyrimidinyl)methyl]-2,6-dimethoxyphenol, 4'-Hydroxytrimethoprim, 4-Demethyl-trimethoprim, 2,4-diamino-5-(3,5-dimethoxy-4-hydroxybenzyl)pyrimidine, 4-((2,4-Diamino-5-pyrimidinyl)methyl)-2,6-dimethoxyphenol, Phenol, 4-((2,4-diamino-5-pyrimidinyl)methyl)-2,6-dimethoxy-, Phenol, 4-[(2,4-diamino-5-pyrimidinyl)methyl]-2,6-dimethoxy-, 4'-DTMP, 2,4-diamino-5-(3',5'-dimethoxy-4'-hydroxybenzyl)-pyrimidine

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of 4-((2,4-Diaminopyrimidin-5-yl)methyl)-2,6-dimethoxyphenol?

The CAS Registry Number of 4-((2,4-Diaminopyrimidin-5-yl)methyl)-2,6-dimethoxyphenol is 21253-58-7. It is also known as 4-Demethyltrimethoprim, 4-[(2,4-Diamino-5-pyrimidinyl)methyl]-2,6-dimethoxyphenol, 4'-Hydroxytrimethoprim.

What is the molecular formula and molecular weight of 4-((2,4-Diaminopyrimidin-5-yl)methyl)-2,6-dimethoxyphenol?

4-((2,4-Diaminopyrimidin-5-yl)methyl)-2,6-dimethoxyphenol has the molecular formula C13H16N4O3 and a molecular weight of 276.29 g/mol. Its IUPAC name is 4-[(2,4-diaminopyrimidin-5-yl)methyl]-2,6-dimethoxyphenol.

What is 4-((2,4-Diaminopyrimidin-5-yl)methyl)-2,6-dimethoxyphenol used for?

4-((2,4-Diaminopyrimidin-5-yl)methyl)-2,6-dimethoxyphenol is supplied as a characterised reference material related to Trimethoprim. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of 4-((2,4-Diaminopyrimidin-5-yl)methyl)-2,6-dimethoxyphenol can I order?

We supply 4-((2,4-Diaminopyrimidin-5-yl)methyl)-2,6-dimethoxyphenol in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with 4-((2,4-Diaminopyrimidin-5-yl)methyl)-2,6-dimethoxyphenol?

Yes. Every lot of 4-((2,4-Diaminopyrimidin-5-yl)methyl)-2,6-dimethoxyphenol is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can 4-((2,4-Diaminopyrimidin-5-yl)methyl)-2,6-dimethoxyphenol be shipped internationally?

Yes. We export 4-((2,4-Diaminopyrimidin-5-yl)methyl)-2,6-dimethoxyphenol worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.