Tryptophan - Impurity G | CAS 21704-80-3

Name: Tryptophan - Impurity G
Brand: Vaqora Chemicals
SKU: VQ-028563

About Tryptophan - Impurity G

Tryptophan - Impurity G (CAS 21704-80-3) is an impurity of Tryptophan offered by Vaqora Chemicals. With the molecular formula C11H12N2O3, it has a molar mass of 220.22 g/mol. Its systematic (IUPAC) name is (2S)-2-amino-3-(2-hydroxy-1H-indol-3-yl)propanoic acid. It is also known as Tryptophan EP Impurity G or 2-Hydroxy-Tryptophan.

It is supplied as a solid. Keep the vial tightly closed, protected from light and humidity, at the temperature stated on the Certificate of Analysis. Under GHS it is labelled “Warning”, so handle it with suitable PPE and consult the SDS.

This Tryptophan impurity supports analytical method development and validation (AMV), batch release testing and the impurity sections of ANDA and DMF filings. Typical end-use sectors are pharmaceutical manufacturing and academic and industrial research.

Vaqora Chemicals supplies Tryptophan - Impurity G in 10 mg, 25 mg, 50 mg and 100 mg packs, each shipped with a Certificate of Analysis (COA), and exports worldwide.

Typical applications

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Industries

Related to Tryptophan

View every impurity, metabolite and intermediate we list for Tryptophan.

Tryptophan impurities

Specifications & identifiers

Chemical identifiers
Product name	Tryptophan - Impurity G
Catalogue No.	VQ-028563
CAS Number	21704-80-3
IUPAC name	(2S)-2-amino-3-(2-hydroxy-1H-indol-3-yl)propanoic acid
Molecular formula	C₁₁H₁₂N₂O₃
Molecular weight	220.22 g/mol
Exact mass	220.0848
Grade	Reference Standard
HSN code	38229090
InChIKey	VAUYGGXCASQWHK-QMMMGPOBSA-N
SMILES	C1=CC=C2C(=C1)C(=C(N2)O)C[C@@H](C(=O)O)N
PubChem CID	17754204

Physical properties
Physical form	Solid
LogP (XLogP3)	-1.3
H-bond donors / acceptors	4 / 4
TPSA	99.3 Å²
Synonyms	Tryptophan EP Impurity G, 2-Hydroxy-Tryptophan, 2-hydroxytryptophan, (S)-2-Amino-3-(2-hydroxy-1H-indol-3-yl)propanoic acid, L-Tryptophan, 2-hydroxy-, 2-amino-3-(2-hydroxy-1H-indol-3-yl)propanoic acid, 2-Hydroxy-L-tryptophan (H-L-Trp(2-OH)-OH)

Safety & hazard information (GHS)

Harmful / irritant

Signal word: Warning

Hazard statements

H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation

Precautionary statements: P261, P264, P264 + P265, P270, P271, P280, P301 + P317, P302 + P352, P304 + P340, P305 + P351 + P338, P319, P321, P330, P332 + P317, P337 + P317, P362 + P364, P403 + P233, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Tryptophan - Impurity G?

The CAS Registry Number of Tryptophan - Impurity G is 21704-80-3. It is also known as Tryptophan EP Impurity G, 2-Hydroxy-Tryptophan, 2-hydroxytryptophan.

What is the molecular formula and molecular weight of Tryptophan - Impurity G?

Tryptophan - Impurity G has the molecular formula C11H12N2O3 and a molecular weight of 220.22 g/mol. Its IUPAC name is (2S)-2-amino-3-(2-hydroxy-1H-indol-3-yl)propanoic acid.

What is Tryptophan - Impurity G used for?

Tryptophan - Impurity G is supplied as a characterised reference material related to Tryptophan. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Tryptophan - Impurity G can I order?

We supply Tryptophan - Impurity G in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Tryptophan - Impurity G?

Yes. Every lot of Tryptophan - Impurity G is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Tryptophan - Impurity G be shipped internationally?

Yes. Tryptophan - Impurity G is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.