Isoescin IA

About Isoescin IA

Isoescin IA is an impurity of Escin carrying the CAS registry number 219944-39-5. Its molecular formula is C55H86O24 and its molecular weight is 1131.3 g/mol. Common synonyms include Aescin C and Escin iva.

The product is provided as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. Under GHS it is labelled “Warning”, so handle it with suitable PPE and consult the SDS.

This Escin impurity supports analytical method development and validation (AMV), batch release testing and the impurity sections of ANDA and DMF filings. Typical end-use sectors are pharmaceutical manufacturing and academic and industrial research.

We offer Isoescin IA in 10 mg, 25 mg, 50 mg and 100 mg packs with a batch-specific COA, and ship to customers worldwide.

Typical applications

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Industries

Related to Escin

View every impurity, metabolite and intermediate we list for Escin.

Escin impurities

Specifications & identifiers

Chemical identifiers
Product name	Isoescin IA
Catalogue No.	VQ-030549
CAS Number	219944-39-5
IUPAC name	(2S,3S,4S,5R,6R)-6-[[(3S,4S,4aR,6aR,6bS,8R,8aR,9R,10R,12aS,14aR,14bR)-8a-(acetyloxymethyl)-8,9-dihydroxy-4-(hydroxymethyl)-4,6a,6b,11,11,14b-hexamethyl-10-[(E)-2-methylbut-2-enoyl]oxy-1,2,3,4a,5,6,7,8,9,10,12,12a,14,14a-tetradecahydropicen-3-yl]oxy]-4-hydroxy-3,5-bis[[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy]oxane-2-carboxylic acid
Molecular formula	C₅₅H₈₆O₂₄
Molecular weight	1131.3 g/mol
Exact mass	1130.5509
Grade	Reference Standard
HSN code	38229090
InChIKey	YOSIWGSGLDDTHJ-IVKVKCDBSA-N
PubChem CID	6476032

Physical properties
Physical form	Solid
LogP (XLogP3)	0.1
H-bond donors / acceptors	13 / 24
TPSA	388 Å²
Synonyms	Aescin C, Escin iva, Isoescin ia (constituent of horse chestnut), Isoescin ia (constituent of horse chestnut) [DSC], isoescine Ia, Isoescin IAEscin iva

Safety & hazard information (GHS)

Harmful / irritant

Signal word: Warning

Hazard statements

H302+H332Harmful if swallowed or if inhaled
H302Harmful if swallowed
H332Harmful if inhaled

Precautionary statements: P261, P264, P270, P271, P301 + P317, P304 + P340, P317, P330, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Isoescin IA?

The CAS Registry Number of Isoescin IA is 219944-39-5. It is also known as Aescin C, Escin iva, Isoescin ia (constituent of horse chestnut).

What is the molecular formula and molecular weight of Isoescin IA?

Isoescin IA has the molecular formula C55H86O24 and a molecular weight of 1131.3 g/mol.

What is Isoescin IA used for?

Isoescin IA is supplied as a characterised reference material related to Escin. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Isoescin IA can I order?

We supply Isoescin IA in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Isoescin IA?

Yes. Every lot of Isoescin IA is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Isoescin IA be shipped internationally?

Yes. Isoescin IA is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.