Hydroxy O-Demethyl Apixaban Sulfate

About Hydroxy O-Demethyl Apixaban Sulfate

Hydroxy O-Demethyl Apixaban Sulfate is a metabolite or degradation product of Apixaban carrying the CAS registry number 2203515-00-6. Formula C24H23N5O8S, molecular weight 541.5 g/mol. Common synonyms include Hydroxy O-Desmethyl Apixaban Sulfate.

The product is provided as a solid. Keep the vial tightly closed, protected from light and humidity, at the temperature stated on the Certificate of Analysis. Good laboratory practice and suitable PPE are recommended during handling.

It is used in metabolite identification, stability-indicating method development and impurity profiling of Apixaban, as well as in QC testing and ANDA/DMF documentation. Our customers for this product work in pharmaceutical manufacturing and academic and industrial research.

Standard pack sizes are 10 mg, 25 mg, 50 mg and 100 mg, and every batch ships with a Certificate of Analysis (COA) and we export worldwide.

Typical applications

Metabolite identification
Stability-indicating methods
Impurity profiling

Industries

Related to Apixaban

View every impurity, metabolite and intermediate we list for Apixaban.

Apixaban impurities

Specifications & identifiers

Chemical identifiers
Product name	Hydroxy O-Demethyl Apixaban Sulfate
Catalogue No.	VQ-043042
CAS Number	2203515-00-6
IUPAC name	[4-[3-carbamoyl-6-[4-(3-hydroxy-2-oxopiperidin-1-yl)phenyl]-7-oxo-4,5-dihydropyrazolo[5,4-c]pyridin-1-yl]phenyl] hydrogen sulfate
Molecular formula	C₂₄H₂₃N₅O₈S
Molecular weight	541.5 g/mol
Exact mass	541.1267
Grade	Reference Standard
HSN code	38229090
InChIKey	SQPPNLDDZVQFSI-UHFFFAOYSA-N
SMILES	C1CC(C(=O)N(C1)C2=CC=C(C=C2)N3CCC4=C(C3=O)N(N=C4C(=O)N)C5=CC=C(C=C5)OS(=O)(=O)O)O
PubChem CID	171370673

Physical properties
Physical form	Solid
LogP (XLogP3)	0.8
H-bond donors / acceptors	3 / 9
TPSA	194 Å²

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Hydroxy O-Demethyl Apixaban Sulfate?

The CAS Registry Number of Hydroxy O-Demethyl Apixaban Sulfate is 2203515-00-6. It is also known as Hydroxy O-Desmethyl Apixaban Sulfate.

What is the molecular formula and molecular weight of Hydroxy O-Demethyl Apixaban Sulfate?

Hydroxy O-Demethyl Apixaban Sulfate has the molecular formula C24H23N5O8S and a molecular weight of 541.5 g/mol. Its IUPAC name is [4-[3-carbamoyl-6-[4-(3-hydroxy-2-oxopiperidin-1-yl)phenyl]-7-oxo-4,5-dihydropyrazolo[5,4-c]pyridin-1-yl]phenyl] hydrogen sulfate.

What is Hydroxy O-Demethyl Apixaban Sulfate used for?

Hydroxy O-Demethyl Apixaban Sulfate is supplied as a characterised reference material related to Apixaban. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Hydroxy O-Demethyl Apixaban Sulfate can I order?

We supply Hydroxy O-Demethyl Apixaban Sulfate in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Hydroxy O-Demethyl Apixaban Sulfate?

Yes. Every lot of Hydroxy O-Demethyl Apixaban Sulfate is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Hydroxy O-Demethyl Apixaban Sulfate be shipped internationally?

Yes. We export Hydroxy O-Demethyl Apixaban Sulfate worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.