(1R,2S)-2-(3,5-Difluorophenyl)cyclopropanamine 220352-50-1

About (1R,2S)-2-(3,5-Difluorophenyl)cyclopropanamine

(1R,2S)-2-(3,5-Difluorophenyl)cyclopropanamine is an impurity of Ticagrelor carrying the CAS registry number 220352-50-1. The compound has the formula C9H9F2N, corresponding to a molecular weight of 169.17 g/mol. Its systematic (IUPAC) name is trans-(1R,2S)-2-(3,5-difluorophenyl)cyclopropan-1-amine.

It is supplied as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. Under GHS it is labelled “Danger”, so handle it with suitable PPE and consult the SDS.

Pharmaceutical QC and development laboratories use this impurity standard of Ticagrelor to develop and validate HPLC methods, to set specification limits and to document impurity profiles in ANDA and DMF submissions. Buyers come mainly from pharmaceutical manufacturing and academic and industrial research.

Standard pack sizes are 10 mg, 25 mg, 50 mg and 100 mg, and every batch ships with a Certificate of Analysis (COA) and we export worldwide.

Typical applications

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Industries

Related to Ticagrelor

View every impurity, metabolite and intermediate we list for Ticagrelor.

Ticagrelor impurities

Specifications & identifiers

Chemical identifiers
Product name	(1R,2S)-2-(3,5-Difluorophenyl)cyclopropanamine
Catalogue No.	VQ-034238
CAS Number	220352-50-1
IUPAC name	trans-(1R,2S)-2-(3,5-difluorophenyl)cyclopropan-1-amine
Molecular formula	C₉H₉F₂N
Molecular weight	169.17 g/mol
Exact mass	169.0703
Grade	Reference Standard
HSN code	38229090
InChIKey	XLQLRKKOZIANSJ-DTWKUNHWSA-N
SMILES	C1[C@H]([C@@H]1N)C2=CC(=CC(=C2)F)F
PubChem CID	54476052

Physical properties
Physical form	Solid
LogP (XLogP3)	1.4
H-bond donors / acceptors	1 / 3
TPSA	26 Å²

Safety & hazard information (GHS)

Corrosive

Harmful / irritant

Signal word: Danger

Hazard statements

H302Harmful if swallowed
H315Causes skin irritation
H318Causes serious eye damage
H335May cause respiratory irritation

Precautionary statements: P261, P264, P264 + P265, P270, P271, P280, P301 + P317, P302 + P352, P304 + P340, P305 + P354 + P338, P317, P319, P321, P330, P332 + P317, P362 + P364, P403 + P233, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of (1R,2S)-2-(3,5-Difluorophenyl)cyclopropanamine?

The CAS Registry Number of (1R,2S)-2-(3,5-Difluorophenyl)cyclopropanamine is 220352-50-1. It is also known as Trans-2-(3,5-difluorophenyl)cyclopropan-1-amine, rac-(1R,2S)-2-(3,5-difluorophenyl)cyclopropan-1-amine, (1R,2S)-2-(3,5-difluorophenyl)cyclopropan-1-amine.

What is the molecular formula and molecular weight of (1R,2S)-2-(3,5-Difluorophenyl)cyclopropanamine?

(1R,2S)-2-(3,5-Difluorophenyl)cyclopropanamine has the molecular formula C9H9F2N and a molecular weight of 169.17 g/mol. Its IUPAC name is trans-(1R,2S)-2-(3,5-difluorophenyl)cyclopropan-1-amine.

What is (1R,2S)-2-(3,5-Difluorophenyl)cyclopropanamine used for?

(1R,2S)-2-(3,5-Difluorophenyl)cyclopropanamine is supplied as a characterised reference material related to Ticagrelor. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of (1R,2S)-2-(3,5-Difluorophenyl)cyclopropanamine can I order?

We supply (1R,2S)-2-(3,5-Difluorophenyl)cyclopropanamine in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with (1R,2S)-2-(3,5-Difluorophenyl)cyclopropanamine?

Yes. Every lot of (1R,2S)-2-(3,5-Difluorophenyl)cyclopropanamine is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can (1R,2S)-2-(3,5-Difluorophenyl)cyclopropanamine be shipped internationally?

Yes. (1R,2S)-2-(3,5-Difluorophenyl)cyclopropanamine is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.