Apixaban Amino Acid Impurity

About Apixaban Amino Acid Impurity

Apixaban Amino Acid Impurity is an impurity of Apixaban carrying the CAS registry number 2206825-87-6, specified at 95% purity. Its molecular formula is C25H27N5O5 and its molecular weight is 477.5 g/mol. Its systematic (IUPAC) name is 5-[4-[3-carbamoyl-1-(4-methoxyphenyl)-7-oxo-4,5-dihydropyrazolo[5,4-c]pyridin-6-yl]anilino]pentanoic acid. Alternative names: Apixaban Open Ring Acid and Apixaban Impurity 39.

The product is provided as a solid. Keep the vial tightly closed, protected from light and humidity, at the temperature stated on the Certificate of Analysis. The GHS classification uses the signal word “Warning”, so appropriate gloves, eye protection and ventilation are recommended.

This Apixaban impurity supports analytical method development and validation (AMV), batch release testing and the impurity sections of ANDA and DMF filings. It is used across pharmaceutical manufacturing and academic and industrial research.

Available in 10 mg, 25 mg, 50 mg and 100 mg packs, Apixaban Amino Acid Impurity is dispatched with a Certificate of Analysis (COA) to destinations worldwide. This item is currently in stock for prompt dispatch.

Typical applications

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Industries

Related to Apixaban

View every impurity, metabolite and intermediate we list for Apixaban.

Apixaban impurities

Specifications & identifiers

Chemical identifiers
Product name	Apixaban Amino Acid Impurity
Catalogue No.	VQ-004396
CAS Number	2206825-87-6
Other CAS	2241139-69-3
IUPAC name	5-[4-[3-carbamoyl-1-(4-methoxyphenyl)-7-oxo-4,5-dihydropyrazolo[5,4-c]pyridin-6-yl]anilino]pentanoic acid
Molecular formula	C₂₅H₂₇N₅O₅
Molecular weight	477.5 g/mol
Exact mass	477.2012
Grade	Reference Standard
Purity / assay	95%
HSN code	38229090
InChIKey	JYXZVSMVCZWUPI-UHFFFAOYSA-N
SMILES	COC1=CC=C(C=C1)N2C3=C(CCN(C3=O)C4=CC=C(C=C4)NCCCCC(=O)O)C(=N2)C(=O)N
PubChem CID	90287004

Physical properties
Physical form	Solid
LogP (XLogP3)	2.7
H-bond donors / acceptors	3 / 7
TPSA	140 Å²
Synonyms	Apixaban Open Ring Acid, Apixaban Impurity 39, Apixaban Open Chain Acid, Apixaban Open-ring Acid Impurity, Apixaban Impurity 13 Sodium Salt

Safety & hazard information (GHS)

Harmful / irritant

Signal word: Warning

Hazard statements

H302Harmful if swallowed
H312Harmful in contact with skin
H315Causes skin irritation
H319Causes serious eye irritation
H332Harmful if inhaled
H335May cause respiratory irritation

Precautionary statements: P261, P264, P264 + P265, P270, P271, P280, P301 + P317, P302 + P352, P304 + P340, P305 + P351 + P338, P317, P319, P321, P330, P332 + P317, P337 + P317, P362 + P364, P403 + P233, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Apixaban Amino Acid Impurity?

The CAS Registry Number of Apixaban Amino Acid Impurity is 2206825-87-6. It is also known as Apixaban Open Ring Acid, Apixaban Impurity 39, Apixaban Open Chain Acid.

What is the molecular formula and molecular weight of Apixaban Amino Acid Impurity?

Apixaban Amino Acid Impurity has the molecular formula C25H27N5O5 and a molecular weight of 477.5 g/mol. Its IUPAC name is 5-[4-[3-carbamoyl-1-(4-methoxyphenyl)-7-oxo-4,5-dihydropyrazolo[5,4-c]pyridin-6-yl]anilino]pentanoic acid.

What is Apixaban Amino Acid Impurity used for?

Apixaban Amino Acid Impurity is supplied as a characterised reference material related to Apixaban. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Apixaban Amino Acid Impurity can I order?

We supply Apixaban Amino Acid Impurity in Reference Standard (95%) grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Apixaban Amino Acid Impurity?

Yes. Every lot of Apixaban Amino Acid Impurity is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Apixaban Amino Acid Impurity be shipped internationally?

Yes. Apixaban Amino Acid Impurity is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.