Calcifediol EP Impurity B

Name: Calcifediol EP Impurity B
Brand: Vaqora Chemicals
SKU: VQ-021045

About Calcifediol EP Impurity B

Vaqora Chemicals supplies Calcifediol EP Impurity B, a pharmacopeial impurity of Calcifediol registered under CAS number 22145-68-2. The compound has the formula C27H44O2, corresponding to a molecular weight of 400.6 g/mol. It is also known as Calcifediol - Impurity B or 25-Hydroxy-7-dehydrocholesterol.

The product is provided as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. Under GHS it is labelled “Danger”, so handle it with suitable PPE and consult the SDS.

As a characterised impurity of Calcifediol, it is used for analytical method development, method validation (AMV) and routine quality-control testing, and it supports ANDA and DMF regulatory filings. Typical end-use sectors are pharmaceutical manufacturing and academic and industrial research.

Vaqora Chemicals supplies Calcifediol EP Impurity B in 10 mg, 25 mg, 50 mg and 100 mg packs, each shipped with a Certificate of Analysis (COA), and exports worldwide.

Typical applications

Pharmacopeial method verification
Impurity profiling
QC release testing
ANDA / DMF filings

Industries

Related to Calcifediol

View every impurity, metabolite and intermediate we list for Calcifediol.

Calcifediol impurities

Grade guides

Specifications & identifiers

Chemical identifiers
Product name	Calcifediol EP Impurity B
Catalogue No.	VQ-021045
CAS Number	22145-68-2
IUPAC name	(3S,9S,10R,13R,14R,17R)-17-[(2R)-6-hydroxy-6-methylheptan-2-yl]-10,13-dimethyl-2,3,4,9,11,12,14,15,16,17-decahydro-1H-cyclopenta[a]phenanthren-3-ol
Molecular formula	C₂₇H₄₄O₂
Molecular weight	400.6 g/mol
Exact mass	400.3341
Grade	Reference Standard
HSN code	38229090
InChIKey	JJFYNCJHSCTBPW-TVQCKQBJSA-N
SMILES	C[C@H](CCCC(C)(C)O)[C@H]1CC[C@@H]2[C@@]1(CC[C@H]3C2=CC=C4[C@@]3(CC[C@@H](C4)O)C)C
PubChem CID	9908983

Physical properties
Physical form	Solid
LogP (XLogP3)	6.2
H-bond donors / acceptors	2 / 2
TPSA	40.5 Å²
Synonyms	Calcifediol - Impurity B, 25-Hydroxy-7-dehydrocholesterol, cholesta-5,7-diene-3beta,25-diol, 7-Dehydro-25-hydroxycholesterol, 25-Hydroxy-7-dehydrocholesterol, (-)-, 25-hydroxy-7-DHC, Impurity B of Calcifediol, (3beta)-cholesta-5,7-diene-3,25-diol, Cholesta-5,7-diene-3,25-diol, (3beta)-, Calcifediol Impurity 13, 25-OH-7-DHC, cholest-5,7-diene-3beta,25-diol

Safety & hazard information (GHS)

Toxic

Health hazard

Signal word: Danger

Hazard statements

H300Fatal if swallowed
H310Fatal in contact with skin
H330Fatal if inhaled
H372Causes damage to organs through prolonged or repeated exposure

Precautionary statements: P260, P262, P264, P270, P271, P280, P284, P301 + P316, P302 + P352, P304 + P340, P316, P319, P320, P321, P330, P361 + P364, P403 + P233, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Calcifediol EP Impurity B?

The CAS Registry Number of Calcifediol EP Impurity B is 22145-68-2. It is also known as Calcifediol - Impurity B, 25-Hydroxy-7-dehydrocholesterol, cholesta-5,7-diene-3beta,25-diol.

What is the molecular formula and molecular weight of Calcifediol EP Impurity B?

Calcifediol EP Impurity B has the molecular formula C27H44O2 and a molecular weight of 400.6 g/mol. Its IUPAC name is (3S,9S,10R,13R,14R,17R)-17-[(2R)-6-hydroxy-6-methylheptan-2-yl]-10,13-dimethyl-2,3,4,9,11,12,14,15,16,17-decahydro-1H-cyclopenta[a]phenanthren-3-ol.

What is Calcifediol EP Impurity B used for?

Calcifediol EP Impurity B is supplied as a characterised reference material related to Calcifediol. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Calcifediol EP Impurity B can I order?

We supply Calcifediol EP Impurity B in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Calcifediol EP Impurity B?

Yes. Every lot of Calcifediol EP Impurity B is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Calcifediol EP Impurity B be shipped internationally?

Yes. Calcifediol EP Impurity B is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.