Palonosetron Impurity 4

About Palonosetron Impurity 4

Palonosetron Impurity 4 is an impurity of Palonosetron carrying the CAS registry number 2216753-67-0, specified at 96.4% purity. Formula C18H24N2O, molecular weight 284.4 g/mol. The IUPAC name is (1S)-N-[(3R)-1-azabicyclo[2.2.2]octan-3-yl]-1,2,3,4-tetrahydronaphthalene-1-carboxamide. It is also known as Palonosetron Impurity 67 or Palonosetron Hydrochloride Impurity A.

It is supplied as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. Good laboratory practice and suitable PPE are recommended during handling.

As a characterised impurity of Palonosetron, it is used for analytical method development, method validation (AMV) and routine quality-control testing, and it supports ANDA and DMF regulatory filings. Buyers come mainly from pharmaceutical manufacturing and academic and industrial research.

We offer Palonosetron Impurity 4 in 5 mg packs with a batch-specific COA, and ship to customers worldwide. Stock is available for quick dispatch.

Typical applications

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Industries

Related to Palonosetron

View every impurity, metabolite and intermediate we list for Palonosetron.

Palonosetron impurities

Specifications & identifiers

Chemical identifiers
Product name	Palonosetron Impurity 4
Catalogue No.	VQ-005484
CAS Number	2216753-67-0
IUPAC name	(1S)-N-[(3R)-1-azabicyclo[2.2.2]octan-3-yl]-1,2,3,4-tetrahydronaphthalene-1-carboxamide
Molecular formula	C₁₈H₂₄N₂O
Molecular weight	284.4 g/mol
Exact mass	284.1889
Grade	Reference Standard
Purity / assay	96.4%
HSN code	38229090
InChIKey	KOAZNWLKDYIEHQ-IRXDYDNUSA-N
SMILES	C1C[C@@H](C2=CC=CC=C2C1)C(=O)N[C@H]3CN4CCC3CC4
PubChem CID	29933423

Physical properties
Physical form	Solid
LogP (XLogP3)	2.7
H-bond donors / acceptors	1 / 2
TPSA	32.3 Å²
Synonyms	rel-(1S)-N-(3R)-1-Azabicyclo[2.2.2]oct-3-yl-1,2,3,4-tetrahydro-1-naphthalenecarboxamide, (S)-N-((R)-quinuclidin-3-yl)-1,2,3,4-tetrahydronaphthalene-1-carboxamide, Palonosetron Impurity 67, Palonosetron Hydrochloride Impurity A, Rel-(S)-N-((R)-quinuclidin-3-yl)-1,2,3,4-tetrahydronaphthalene-1-carboxamide

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Palonosetron Impurity 4?

The CAS Registry Number of Palonosetron Impurity 4 is 2216753-67-0. It is also known as rel-(1S)-N-(3R)-1-Azabicyclo[2.2.2]oct-3-yl-1,2,3,4-tetrahydro-1-naphthalenecarboxamide, (S)-N-((R)-quinuclidin-3-yl)-1,2,3,4-tetrahydronaphthalene-1-carboxamide, Palonosetron Impurity 67.

What is the molecular formula and molecular weight of Palonosetron Impurity 4?

Palonosetron Impurity 4 has the molecular formula C18H24N2O and a molecular weight of 284.4 g/mol. Its IUPAC name is (1S)-N-[(3R)-1-azabicyclo[2.2.2]octan-3-yl]-1,2,3,4-tetrahydronaphthalene-1-carboxamide.

What is Palonosetron Impurity 4 used for?

Palonosetron Impurity 4 is supplied as a characterised reference material related to Palonosetron. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Palonosetron Impurity 4 can I order?

We supply Palonosetron Impurity 4 in Reference Standard (96.4%) grade, in 5 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Palonosetron Impurity 4?

Yes. Every lot of Palonosetron Impurity 4 is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Palonosetron Impurity 4 be shipped internationally?

Yes. We export Palonosetron Impurity 4 worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.