Methyl 3-benzoyl-2-oxoindoline-6-carboxylate 2218446-42-3

About Methyl 3-benzoyl-2-oxoindoline-6-carboxylate

Methyl 3-benzoyl-2-oxoindoline-6-carboxylate is a process intermediate or related compound of Nintedanib carrying the CAS registry number 2218446-42-3. The compound has the formula C17H13NO4, corresponding to a molecular weight of 295.29 g/mol. The IUPAC name is methyl 3-benzoyl-2-oxo-1,3-dihydroindole-6-carboxylate.

It is supplied as a solid. Store the standard in its sealed vial, protected from light and moisture, and follow the storage condition printed on the COA. Good laboratory practice and suitable PPE are recommended during handling.

It is a process intermediate or related compound in the synthesis of Nintedanib, useful for route development, impurity fate-and-purge studies and analytical method development. Typical end-use sectors are pharmaceutical manufacturing and academic and industrial research.

Available in 10 mg, 25 mg, 50 mg and 100 mg packs, Methyl 3-benzoyl-2-oxoindoline-6-carboxylate is dispatched with a Certificate of Analysis (COA) to destinations worldwide.

Typical applications

API route development
Impurity fate & purge studies
Analytical method development

Industries

Related to Nintedanib

View every impurity, metabolite and intermediate we list for Nintedanib.

Nintedanib impurities

Specifications & identifiers

Chemical identifiers
Product name	Methyl 3-benzoyl-2-oxoindoline-6-carboxylate
Catalogue No.	VQ-049254
CAS Number	2218446-42-3
IUPAC name	methyl 3-benzoyl-2-oxo-1,3-dihydroindole-6-carboxylate
Molecular formula	C₁₇H₁₃NO₄
Molecular weight	295.29 g/mol
Exact mass	295.0845
HSN code	2933
InChIKey	MQTYFNIIXWRDNZ-UHFFFAOYSA-N
SMILES	COC(=O)C1=CC2=C(C=C1)C(C(=O)N2)C(=O)C3=CC=CC=C3
PubChem CID	141512319

Physical properties
Physical form	Solid
LogP (XLogP3)	2.2
H-bond donors / acceptors	1 / 4
TPSA	72.5 Å²

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Methyl 3-benzoyl-2-oxoindoline-6-carboxylate?

The CAS Registry Number of Methyl 3-benzoyl-2-oxoindoline-6-carboxylate is 2218446-42-3.

What is the molecular formula and molecular weight of Methyl 3-benzoyl-2-oxoindoline-6-carboxylate?

Methyl 3-benzoyl-2-oxoindoline-6-carboxylate has the molecular formula C17H13NO4 and a molecular weight of 295.29 g/mol. Its IUPAC name is methyl 3-benzoyl-2-oxo-1,3-dihydroindole-6-carboxylate.

What is Methyl 3-benzoyl-2-oxoindoline-6-carboxylate used for?

Methyl 3-benzoyl-2-oxoindoline-6-carboxylate is supplied as a characterised reference material related to Nintedanib. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Methyl 3-benzoyl-2-oxoindoline-6-carboxylate can I order?

We supply Methyl 3-benzoyl-2-oxoindoline-6-carboxylate, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Methyl 3-benzoyl-2-oxoindoline-6-carboxylate?

Yes. Every lot of Methyl 3-benzoyl-2-oxoindoline-6-carboxylate is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Methyl 3-benzoyl-2-oxoindoline-6-carboxylate be shipped internationally?

Yes. We export Methyl 3-benzoyl-2-oxoindoline-6-carboxylate worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.