(E)-4-(2,4,5-Trifluorophenyl)but-3-enoic acid 2226094-64-8

About (E)-4-(2,4,5-Trifluorophenyl)but-3-enoic acid

(E)-4-(2,4,5-Trifluorophenyl)but-3-enoic acid is an impurity of Sitagliptin carrying the CAS registry number 2226094-64-8. Its molecular formula is C10H7F3O2 and its molecular weight is 216.16 g/mol.

The product is provided as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. Good laboratory practice and suitable PPE are recommended during handling.

As a characterised impurity of Sitagliptin, it is used for analytical method development, method validation (AMV) and routine quality-control testing, and it supports ANDA and DMF regulatory filings. It is used across pharmaceutical manufacturing and academic and industrial research.

Available in 10 mg, 25 mg, 50 mg and 100 mg packs, (E)-4-(2,4,5-Trifluorophenyl)but-3-enoic acid is dispatched with a Certificate of Analysis (COA) to destinations worldwide. A Safety Data Sheet (SDS) and technical specifications are available on request.

Typical applications

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Industries

Related to Sitagliptin

View every impurity, metabolite and intermediate we list for Sitagliptin.

Sitagliptin impurities

Specifications & identifiers

Chemical identifiers
Product name	(E)-4-(2,4,5-Trifluorophenyl)but-3-enoic acid
Catalogue No.	VQ-042206
CAS Number	2226094-64-8
IUPAC name	(E)-4-(2,4,5-trifluorophenyl)but-3-enoic acid
Molecular formula	C₁₀H₇F₃O₂
Molecular weight	216.16 g/mol
Exact mass	216.0398
Grade	Reference Standard
HSN code	38229090
InChIKey	LOGLMTFFRYPVHZ-OWOJBTEDSA-N
SMILES	C1=C(C(=CC(=C1F)F)F)/C=C/CC(=O)O
PubChem CID	168437261

Physical properties
Physical form	Solid
LogP (XLogP3)	2.3
H-bond donors / acceptors	1 / 5
TPSA	37.3 Å²

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of (E)-4-(2,4,5-Trifluorophenyl)but-3-enoic acid?

The CAS Registry Number of (E)-4-(2,4,5-Trifluorophenyl)but-3-enoic acid is 2226094-64-8.

What is the molecular formula and molecular weight of (E)-4-(2,4,5-Trifluorophenyl)but-3-enoic acid?

(E)-4-(2,4,5-Trifluorophenyl)but-3-enoic acid has the molecular formula C10H7F3O2 and a molecular weight of 216.16 g/mol. Its IUPAC name is (E)-4-(2,4,5-trifluorophenyl)but-3-enoic acid.

What is (E)-4-(2,4,5-Trifluorophenyl)but-3-enoic acid used for?

(E)-4-(2,4,5-Trifluorophenyl)but-3-enoic acid is supplied as a characterised reference material related to Sitagliptin. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of (E)-4-(2,4,5-Trifluorophenyl)but-3-enoic acid can I order?

We supply (E)-4-(2,4,5-Trifluorophenyl)but-3-enoic acid in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with (E)-4-(2,4,5-Trifluorophenyl)but-3-enoic acid?

Yes. Every lot of (E)-4-(2,4,5-Trifluorophenyl)but-3-enoic acid is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can (E)-4-(2,4,5-Trifluorophenyl)but-3-enoic acid be shipped internationally?

Yes. We export (E)-4-(2,4,5-Trifluorophenyl)but-3-enoic acid worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.