2-Methoxy-17α-ethynyl Estradiol

Name: 2-Methoxy-17α-ethynyl Estradiol
Brand: Vaqora Chemicals
SKU: VQ-043162

About 2-Methoxy-17α-ethynyl Estradiol

Listed under CAS 22415-44-7, 2-Methoxy-17α-ethynyl Estradiol is an impurity of Estradiol available from Vaqora Chemicals. Formula C21H26O3, molecular weight 326.4 g/mol. It is also known as 2-Methoxy-17α-Ethinylestradiol or 2-Methoxyethinyl estradiol.

The product is provided as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. Handle it with standard laboratory precautions and appropriate personal protective equipment.

This Estradiol impurity supports analytical method development and validation (AMV), batch release testing and the impurity sections of ANDA and DMF filings. It is used across pharmaceutical manufacturing and academic and industrial research.

We offer 2-Methoxy-17α-ethynyl Estradiol in 10 mg, 25 mg, 50 mg and 100 mg packs with a batch-specific COA, and ship to customers worldwide. SDS and detailed specification sheets can be requested with your quotation.

Typical applications

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Industries

Related to Estradiol

View every impurity, metabolite and intermediate we list for Estradiol.

Estradiol impurities

Specifications & identifiers

Chemical identifiers
Product name	2-Methoxy-17α-ethynyl Estradiol
Catalogue No.	VQ-043162
CAS Number	22415-44-7
IUPAC name	(8R,9S,13S,14S,17R)-17-ethynyl-2-methoxy-13-methyl-7,8,9,11,12,14,15,16-octahydro-6H-cyclopenta[a]phenanthrene-3,17-diol
Molecular formula	C₂₁H₂₆O₃
Molecular weight	326.4 g/mol
Exact mass	326.1882
Grade	Reference Standard
HSN code	38229090
InChIKey	NRGDXTWZJCEVEB-PVHGPHFFSA-N
SMILES	C[C@]12CC[C@H]3[C@H]([C@@H]1CC[C@]2(C#C)O)CCC4=CC(=C(C=C34)OC)O
PubChem CID	68572

Physical properties
Physical form	Solid
LogP (XLogP3)	3.6
H-bond donors / acceptors	2 / 3
TPSA	49.7 Å²
Synonyms	2-Methoxy-17α-Ethinylestradiol, 2-Methoxyethinyl estradiol, 2-Methoxy-17alpha-ethynylestradiol, 2-Methoxy-Ethynyl Estradiol, 2-Methoxy-17a-ethynyl Estradiol, 2-Methoxy-17alpha-ethynyl Estradiol, 2-Methoxy-19-norpregna-1(10),2,4-trien-20-yne-3,17-diol, 2-Methoxy-17alpha-19-norpregna-1(10),2,4-trien-20-yne-3,17-diol, 19-Norpregna-1,3,5(10)-trien-20-yne-3,17-diol, 2-methoxy-, (17alpha)-

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of 2-Methoxy-17α-ethynyl Estradiol?

The CAS Registry Number of 2-Methoxy-17α-ethynyl Estradiol is 22415-44-7. It is also known as 2-Methoxy-17α-Ethinylestradiol, 2-Methoxyethinyl estradiol, 2-Methoxy-17alpha-ethynylestradiol.

What is the molecular formula and molecular weight of 2-Methoxy-17α-ethynyl Estradiol?

2-Methoxy-17α-ethynyl Estradiol has the molecular formula C21H26O3 and a molecular weight of 326.4 g/mol. Its IUPAC name is (8R,9S,13S,14S,17R)-17-ethynyl-2-methoxy-13-methyl-7,8,9,11,12,14,15,16-octahydro-6H-cyclopenta[a]phenanthrene-3,17-diol.

What is 2-Methoxy-17α-ethynyl Estradiol used for?

2-Methoxy-17α-ethynyl Estradiol is supplied as a characterised reference material related to Estradiol. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of 2-Methoxy-17α-ethynyl Estradiol can I order?

We supply 2-Methoxy-17α-ethynyl Estradiol in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with 2-Methoxy-17α-ethynyl Estradiol?

Yes. Every lot of 2-Methoxy-17α-ethynyl Estradiol is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can 2-Methoxy-17α-ethynyl Estradiol be shipped internationally?

Yes. We export 2-Methoxy-17α-ethynyl Estradiol worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.