3-Isobutyl-9,10-bis(methoxy-d3)-3,4,6,7-tetra… 2244238-17-1

About 3-Isobutyl-9,10-bis(methoxy-d3)-3,4,6,7-tetrahydro-2H-pyrido[2,1-a]isoquinolin-2-one

3-Isobutyl-9,10-bis(methoxy-d3)-3,4,6,7-tetrahydro-2H-pyrido[2,1-a]isoquinolin-2-one is a stable isotope labelled analogue related to Tetrabenazine carrying the CAS registry number 2244238-17-1. Formula C19H25NO3, molecular weight 321.4 g/mol. Its systematic (IUPAC) name is 3-(2-methylpropyl)-9,10-bis(trideuteriomethoxy)-3,4,6,7-tetrahydrobenzo[a]quinolizin-2-one. Alternative names: 1,11B-dedihydro tetrabenazine-d6 and 1,11b-Dedihydrotetrabenazine-D6.

It is supplied as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. Handle it with standard laboratory precautions and appropriate personal protective equipment.

Its mass shift relative to the unlabelled analyte makes it a dependable internal standard for LC-MS/MS assays, improving accuracy in bioanalysis, therapeutic drug monitoring and method validation. Our customers for this product work in pharmaceutical manufacturing and academic and industrial research.

We offer 3-Isobutyl-9,10-bis(methoxy-d3)-3,4,6,7-tetrahydro-2H-pyrido[2,1-a]isoquinolin-2-one in 10 mg, 25 mg, 50 mg and 100 mg packs with a batch-specific COA, and ship to customers worldwide.

Typical applications

LC-MS/MS internal standard
Bioanalytical quantitation
Pharmacokinetic studies

Industries

Related to Tetrabenazine

View every impurity, metabolite and intermediate we list for Tetrabenazine.

Tetrabenazine impurities

Grade guides

Specifications & identifiers

Chemical identifiers
Product name	3-Isobutyl-9,10-bis(methoxy-d3)-3,4,6,7-tetrahydro-2H-pyrido[2,1-a]isoquinolin-2-one
Catalogue No.	VQ-028958
CAS Number	2244238-17-1
IUPAC name	3-(2-methylpropyl)-9,10-bis(trideuteriomethoxy)-3,4,6,7-tetrahydrobenzo[a]quinolizin-2-one
Molecular formula	C₁₉H₂₅NO₃
Molecular weight	321.4 g/mol
Exact mass	321.2211
Grade	Reference Standard
HSN code	38229090
InChIKey	WKGNBYVLCQOPIG-LIJFRPJRSA-N
SMILES	[2H]C([2H])([2H])OC1=C(C=C2C(=C1)CCN3C2=CC(=O)C(C3)CC(C)C)OC([2H])([2H])[2H]
PubChem CID	156596449

Physical properties
Physical form	Solid
LogP (XLogP3)	3.4
H-bond donors / acceptors	0 / 4
TPSA	38.8 Å²

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of 3-Isobutyl-9,10-bis(methoxy-d3)-3,4,6,7-tetrahydro-2H-pyrido[2,1-a]isoquinolin-2-one?

The CAS Registry Number of 3-Isobutyl-9,10-bis(methoxy-d3)-3,4,6,7-tetrahydro-2H-pyrido[2,1-a]isoquinolin-2-one is 2244238-17-1. It is also known as 1,11B-dedihydro tetrabenazine-d6, 1,11b-Dedihydrotetrabenazine-D6, 2H-Benzo(a)quinolizin-2-one, 3,4,6,7-tetrahydro-9,10-di(methoxy-d3)-3-(2-methylpropyl)-.

What is the molecular formula and molecular weight of 3-Isobutyl-9,10-bis(methoxy-d3)-3,4,6,7-tetrahydro-2H-pyrido[2,1-a]isoquinolin-2-one?

3-Isobutyl-9,10-bis(methoxy-d3)-3,4,6,7-tetrahydro-2H-pyrido[2,1-a]isoquinolin-2-one has the molecular formula C19H25NO3 and a molecular weight of 321.4 g/mol. Its IUPAC name is 3-(2-methylpropyl)-9,10-bis(trideuteriomethoxy)-3,4,6,7-tetrahydrobenzo[a]quinolizin-2-one.

What is 3-Isobutyl-9,10-bis(methoxy-d3)-3,4,6,7-tetrahydro-2H-pyrido[2,1-a]isoquinolin-2-one used for?

3-Isobutyl-9,10-bis(methoxy-d3)-3,4,6,7-tetrahydro-2H-pyrido[2,1-a]isoquinolin-2-one is supplied as a characterised reference material related to Tetrabenazine. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of 3-Isobutyl-9,10-bis(methoxy-d3)-3,4,6,7-tetrahydro-2H-pyrido[2,1-a]isoquinolin-2-one can I order?

We supply 3-Isobutyl-9,10-bis(methoxy-d3)-3,4,6,7-tetrahydro-2H-pyrido[2,1-a]isoquinolin-2-one in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with 3-Isobutyl-9,10-bis(methoxy-d3)-3,4,6,7-tetrahydro-2H-pyrido[2,1-a]isoquinolin-2-one?

Yes. Every lot of 3-Isobutyl-9,10-bis(methoxy-d3)-3,4,6,7-tetrahydro-2H-pyrido[2,1-a]isoquinolin-2-one is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can 3-Isobutyl-9,10-bis(methoxy-d3)-3,4,6,7-tetrahydro-2H-pyrido[2,1-a]isoquinolin-2-one be shipped internationally?

Yes. We export 3-Isobutyl-9,10-bis(methoxy-d3)-3,4,6,7-tetrahydro-2H-pyrido[2,1-a]isoquinolin-2-one worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.