Ethyl 4-((3,5-dichloro-4-methoxybenzyl)amino)… 2250242-48-7

Name: Ethyl 4-((3,5-dichloro-4-methoxybenzyl)amino)-2-(methylthio)pyrimidine-5-carboxylate
Brand: Vaqora Chemicals
SKU: VQ-043751

About Ethyl 4-((3,5-dichloro-4-methoxybenzyl)amino)-2-(methylthio)pyrimidine-5-carboxylate

Listed under CAS 2250242-48-7, Ethyl 4-((3,5-dichloro-4-methoxybenzyl)amino)-2-(methylthio)pyrimidine-5-carboxylate is an impurity of Avanafil available from Vaqora Chemicals. The compound has the formula C16H17Cl2N3O3S, corresponding to a molecular weight of 402.3 g/mol. Its systematic (IUPAC) name is ethyl 4-[(3,5-dichloro-4-methoxyphenyl)methylamino]-2-methylsulfanylpyrimidine-5-carboxylate.

It is supplied as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. Handle it with standard laboratory precautions and appropriate personal protective equipment.

As a characterised impurity of Avanafil, it is used for analytical method development, method validation (AMV) and routine quality-control testing, and it supports ANDA and DMF regulatory filings. Our customers for this product work in pharmaceutical manufacturing and academic and industrial research.

Available in 10 mg, 25 mg, 50 mg and 100 mg packs, Ethyl 4-((3,5-dichloro-4-methoxybenzyl)amino)-2-(methylthio)pyrimidine-5-carboxylate is dispatched with a Certificate of Analysis (COA) to destinations worldwide.

Typical applications

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Industries

Related to Avanafil

View every impurity, metabolite and intermediate we list for Avanafil.

Avanafil impurities

Specifications & identifiers

Chemical identifiers
Product name	Ethyl 4-((3,5-dichloro-4-methoxybenzyl)amino)-2-(methylthio)pyrimidine-5-carboxylate
Catalogue No.	VQ-043751
CAS Number	2250242-48-7
IUPAC name	ethyl 4-[(3,5-dichloro-4-methoxyphenyl)methylamino]-2-methylsulfanylpyrimidine-5-carboxylate
Molecular formula	C₁₆H₁₇Cl₂N₃O₃S
Molecular weight	402.3 g/mol
Exact mass	401.0368
Grade	Reference Standard
HSN code	38229090
InChIKey	FVVBUCDFBVBCBE-UHFFFAOYSA-N
SMILES	CCOC(=O)C1=CN=C(N=C1NCC2=CC(=C(C(=C2)Cl)OC)Cl)SC
PubChem CID	138109338

Physical properties
Physical form	Solid
LogP (XLogP3)	4.9
H-bond donors / acceptors	1 / 7
TPSA	98.6 Å²

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Ethyl 4-((3,5-dichloro-4-methoxybenzyl)amino)-2-(methylthio)pyrimidine-5-carboxylate?

The CAS Registry Number of Ethyl 4-((3,5-dichloro-4-methoxybenzyl)amino)-2-(methylthio)pyrimidine-5-carboxylate is 2250242-48-7. It is also known as Avanafil Dichloro Methylthiopyrimidine Ethyl Ester.

What is the molecular formula and molecular weight of Ethyl 4-((3,5-dichloro-4-methoxybenzyl)amino)-2-(methylthio)pyrimidine-5-carboxylate?

Ethyl 4-((3,5-dichloro-4-methoxybenzyl)amino)-2-(methylthio)pyrimidine-5-carboxylate has the molecular formula C16H17Cl2N3O3S and a molecular weight of 402.3 g/mol. Its IUPAC name is ethyl 4-[(3,5-dichloro-4-methoxyphenyl)methylamino]-2-methylsulfanylpyrimidine-5-carboxylate.

What is Ethyl 4-((3,5-dichloro-4-methoxybenzyl)amino)-2-(methylthio)pyrimidine-5-carboxylate used for?

Ethyl 4-((3,5-dichloro-4-methoxybenzyl)amino)-2-(methylthio)pyrimidine-5-carboxylate is supplied as a characterised reference material related to Avanafil. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Ethyl 4-((3,5-dichloro-4-methoxybenzyl)amino)-2-(methylthio)pyrimidine-5-carboxylate can I order?

We supply Ethyl 4-((3,5-dichloro-4-methoxybenzyl)amino)-2-(methylthio)pyrimidine-5-carboxylate in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Ethyl 4-((3,5-dichloro-4-methoxybenzyl)amino)-2-(methylthio)pyrimidine-5-carboxylate?

Yes. Every lot of Ethyl 4-((3,5-dichloro-4-methoxybenzyl)amino)-2-(methylthio)pyrimidine-5-carboxylate is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Ethyl 4-((3,5-dichloro-4-methoxybenzyl)amino)-2-(methylthio)pyrimidine-5-carboxylate be shipped internationally?

Yes. We export Ethyl 4-((3,5-dichloro-4-methoxybenzyl)amino)-2-(methylthio)pyrimidine-5-carboxylate worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.