4-Chloro-3-nitro-5-sulfamoylbenzoic Acid

Name: 4-Chloro-3-nitro-5-sulfamoylbenzoic Acid
Brand: Vaqora Chemicals
SKU: VQ-029534

About 4-Chloro-3-nitro-5-sulfamoylbenzoic Acid

Vaqora Chemicals supplies 4-Chloro-3-nitro-5-sulfamoylbenzoic Acid, an impurity of Bumetanide registered under CAS number 22892-96-2. Its molecular formula is C7H5ClN2O6S and its molecular weight is 280.64 g/mol. Alternative names: 4-Chloro-3-nitro-5-sulphamoylbenzoic acid and 4-chloro-5-nitro-3-sulfamoylbenzoic acid.

It is supplied as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. It carries the GHS signal word “Warning” with 3 hazard statements. Review the Safety Data Sheet before use.

Pharmaceutical QC and development laboratories use this impurity standard of Bumetanide to develop and validate HPLC methods, to set specification limits and to document impurity profiles in ANDA and DMF submissions. Typical end-use sectors are pharmaceutical manufacturing and academic and industrial research.

Vaqora Chemicals supplies 4-Chloro-3-nitro-5-sulfamoylbenzoic Acid in 10 mg, 25 mg, 50 mg and 100 mg packs, each shipped with a Certificate of Analysis (COA), and exports worldwide.

Typical applications

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Industries

Related to Bumetanide

View every impurity, metabolite and intermediate we list for Bumetanide.

Bumetanide impurities

Specifications & identifiers

Chemical identifiers
Product name	4-Chloro-3-nitro-5-sulfamoylbenzoic Acid
Catalogue No.	VQ-029534
CAS Number	22892-96-2
IUPAC name	4-chloro-3-nitro-5-sulfamoylbenzoic acid
Molecular formula	C₇H₅ClN₂O₆S
Molecular weight	280.64 g/mol
Exact mass	279.9557
Grade	Reference Standard
HSN code	38229090
InChIKey	ACYLUAGCBGTEJF-UHFFFAOYSA-N
SMILES	C1=C(C=C(C(=C1[N+](=O)[O-])Cl)S(=O)(=O)N)C(=O)O
PubChem CID	89893

Physical properties
Physical form	Solid
LogP (XLogP3)	0.5
H-bond donors / acceptors	2 / 7
TPSA	152 Å²
Synonyms	4-Chloro-3-nitro-5-sulphamoylbenzoic acid, Benzoic acid, 3-(aminosulfonyl)-4-chloro-5-nitro-, 3-(aminosulfonyl)-4-chloro-5-nitrobenzoic acid, 2-chloro-3-nitro-5-carboxy-benzenesulphonamide, 4-chloro-5-nitro-3-sulfamoylbenzoic acid, 3-nitro-4-chloro-5-sulfamoylbenzoic acid, 5-Aminosulfonyl-4-chloro-3-nitrobenzoic Acid, 4-Chloro-3-nitro-5-sulfamoyl, 4-Chloro-3-nitro-5-sulphamoylbenzoicacid

Safety & hazard information (GHS)

Harmful / irritant

Signal word: Warning

Hazard statements

H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation

Precautionary statements: P261, P264, P264 + P265, P271, P280, P302 + P352, P304 + P340, P305 + P351 + P338, P319, P321, P332 + P317, P337 + P317, P362 + P364, P403 + P233, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of 4-Chloro-3-nitro-5-sulfamoylbenzoic Acid?

The CAS Registry Number of 4-Chloro-3-nitro-5-sulfamoylbenzoic Acid is 22892-96-2. It is also known as 4-Chloro-3-nitro-5-sulphamoylbenzoic acid, Benzoic acid, 3-(aminosulfonyl)-4-chloro-5-nitro-, 3-(aminosulfonyl)-4-chloro-5-nitrobenzoic acid.

What is the molecular formula and molecular weight of 4-Chloro-3-nitro-5-sulfamoylbenzoic Acid?

4-Chloro-3-nitro-5-sulfamoylbenzoic Acid has the molecular formula C7H5ClN2O6S and a molecular weight of 280.64 g/mol. Its IUPAC name is 4-chloro-3-nitro-5-sulfamoylbenzoic acid.

What is 4-Chloro-3-nitro-5-sulfamoylbenzoic Acid used for?

4-Chloro-3-nitro-5-sulfamoylbenzoic Acid is supplied as a characterised reference material related to Bumetanide. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of 4-Chloro-3-nitro-5-sulfamoylbenzoic Acid can I order?

We supply 4-Chloro-3-nitro-5-sulfamoylbenzoic Acid in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with 4-Chloro-3-nitro-5-sulfamoylbenzoic Acid?

Yes. Every lot of 4-Chloro-3-nitro-5-sulfamoylbenzoic Acid is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can 4-Chloro-3-nitro-5-sulfamoylbenzoic Acid be shipped internationally?

Yes. 4-Chloro-3-nitro-5-sulfamoylbenzoic Acid is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.