Nalbuphine Hydrochloride

Name: Nalbuphine Hydrochloride
Brand: Vaqora Chemicals
SKU: VQ-043234

About Nalbuphine Hydrochloride

Nalbuphine Hydrochloride (CAS 23277-43-2) is a high-purity reference standard of Nalbuphine offered by Vaqora Chemicals. Its molecular formula is C21H28ClNO4 and its molecular weight is 393.9 g/mol. It is also known as Nalbuphine Hydrochloride (WSM) or Nalbuphine HCL.

The product is provided as a solid. Keep the vial tightly closed, protected from light and humidity, at the temperature stated on the Certificate of Analysis. Under GHS it is labelled “Danger”, so handle it with suitable PPE and consult the SDS.

As a reference sample of Nalbuphine, it is used for identification, assay and impurity-profiling work during analytical method development, validation (AMV) and routine QC. Typical end-use sectors are pharmaceutical manufacturing and academic and industrial research.

Vaqora Chemicals supplies Nalbuphine Hydrochloride in 10 mg, 25 mg, 50 mg and 100 mg packs, each shipped with a Certificate of Analysis (COA), and exports worldwide.

Typical applications

Identification & assay
Method development & validation
QC reference material

Industries

Related to Nalbuphine

View every impurity, metabolite and intermediate we list for Nalbuphine.

Nalbuphine impurities

Specifications & identifiers

Chemical identifiers
Product name	Nalbuphine Hydrochloride
Catalogue No.	VQ-043234
CAS Number	23277-43-2
IUPAC name	(4R,4aS,7S,7aR,12bS)-3-(cyclobutylmethyl)-1,2,4,5,6,7,7a,13-octahydro-4,12-methanobenzofuro[3,2-e]isoquinoline-4a,7,9-triol;hydrochloride
Molecular formula	C₂₁H₂₈ClNO₄
Molecular weight	393.9 g/mol
Exact mass	393.1707
Grade	Reference Standard
HSN code	38229090
InChIKey	YZLZPSJXMWGIFH-BCXQGASESA-N
SMILES	C1CC(C1)CN2CC[C@]34[C@@H]5[C@H](CC[C@]3([C@H]2CC6=C4C(=C(C=C6)O)O5)O)O.Cl
PubChem CID	5360733

Physical properties
Physical form	Solid
H-bond donors / acceptors	4 / 5
TPSA	73.2 Å²
Synonyms	Nalbuphine Hydrochloride (WSM), Nalbuphine HCL, EN-2234A, Nalbufine hydrochloride, En 2234A, Nalbufina clorhidrato, (5alpha,6alpha)-17-(Cyclobutylmethyl)-4,5-epoxymorphinan-3,6,14-triol hydrochloride, N-Cyclobutylmethyl-14-hydroxydihydronormorphine hydrochloride, 17-cyclobutylmethyl-4,5alpha-epoxymorphinan-3,6alpha,14-triol hydrochloride, Nubain, 17-(Cyclobutylmethyl)-4,5alpha-epoxymorphinan-3,6alpha,14-triol hydrochloride, Nalbuphine hydrochloride (USAN)

Safety & hazard information (GHS)

Toxic

Harmful / irritant

Health hazard

Signal word: Danger

Hazard statements

H300Fatal if swallowed
H302Harmful if swallowed
H310Fatal in contact with skin
H312Harmful in contact with skin
H317May cause an allergic skin reaction
H330Fatal if inhaled
H332Harmful if inhaled
H334May cause allergy or asthma symptoms or breathing difficulties if inhaled

Precautionary statements: P233, P260, P261, P262, P264, P270, P271, P272, P280, P284, P301 + P316, P301 + P317, P302 + P352, P304 + P340, P316, P317, P320, P321, P330, P333 + P317, P342 + P316, P361 + P364, P362 + P364, P403

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Nalbuphine Hydrochloride?

The CAS Registry Number of Nalbuphine Hydrochloride is 23277-43-2. It is also known as Nalbuphine Hydrochloride (WSM), Nalbuphine HCL, EN-2234A.

What is the molecular formula and molecular weight of Nalbuphine Hydrochloride?

Nalbuphine Hydrochloride has the molecular formula C21H28ClNO4 and a molecular weight of 393.9 g/mol.

What is Nalbuphine Hydrochloride used for?

Nalbuphine Hydrochloride is supplied as a characterised reference material related to Nalbuphine. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Nalbuphine Hydrochloride can I order?

We supply Nalbuphine Hydrochloride in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Nalbuphine Hydrochloride?

Yes. Every lot of Nalbuphine Hydrochloride is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Nalbuphine Hydrochloride be shipped internationally?

Yes. Nalbuphine Hydrochloride is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.