Clotrimazole EP Impurity B

About Clotrimazole EP Impurity B

Clotrimazole EP Impurity B is a pharmacopeial impurity of Clotrimazole carrying the CAS registry number 23593-71-7. With the molecular formula C22H17ClN2, it has a molar mass of 344.8 g/mol. Systematically, it is named 1-[(4-chlorophenyl)-diphenylmethyl]imidazole. It is also known as Clotrimazole - Impurity B or CDD-3532.

It is supplied as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. Under GHS it is labelled “Warning”, so handle it with suitable PPE and consult the SDS.

This Clotrimazole impurity supports analytical method development and validation (AMV), batch release testing and the impurity sections of ANDA and DMF filings. Typical end-use sectors are pharmaceutical manufacturing and academic and industrial research.

Available in 10 mg, 25 mg, 50 mg and 100 mg packs, Clotrimazole EP Impurity B is dispatched with a Certificate of Analysis (COA) to destinations worldwide.

Typical applications

Pharmacopeial method verification
Impurity profiling
QC release testing
ANDA / DMF filings

Industries

Related to Clotrimazole

View every impurity, metabolite and intermediate we list for Clotrimazole.

Clotrimazole impurities

Grade guides

Specifications & identifiers

Chemical identifiers
Product name	Clotrimazole EP Impurity B
Catalogue No.	VQ-022243
CAS Number	23593-71-7
IUPAC name	1-[(4-chlorophenyl)-diphenylmethyl]imidazole
Molecular formula	C₂₂H₁₇ClN₂
Molecular weight	344.8 g/mol
Exact mass	344.108
Grade	Reference Standard
HSN code	38229090
InChIKey	BLNLHAFFGFCSRK-UHFFFAOYSA-N
SMILES	C1=CC=C(C=C1)C(C2=CC=CC=C2)(C3=CC=C(C=C3)Cl)N4C=CN=C4
PubChem CID	13073877

Physical properties
Physical form	Solid
LogP (XLogP3)	5
H-bond donors / acceptors	0 / 1
TPSA	17.8 Å²
Synonyms	Clotrimazole - Impurity B, 1-((4-Chlorophenyl)diphenylmethyl)-1H-imidazole, 1-[(4-Chlorophenyl)diphenylmethyl]-1H-imidazole, CDD-3532, 1-((p-Chlorophenyl)diphenylmethyl)imidazole, 1H-Imidazole, 1-((4-chlorophenyl)diphenylmethyl)-, 1-[(p-Chlorophenyl)diphenylmethyl]imidazole, para-Clotrimazole Isomer, Clotrimazole Impurity B, Clotrimazole Impurity A, CDD 3532, Clotrimazole-001

Safety & hazard information (GHS)

Harmful / irritant

Signal word: Warning

Hazard statements

H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
H413May cause long lasting harmful effects to aquatic life

Precautionary statements: P261, P264, P264 + P265, P270, P271, P273, P280, P301 + P317, P302 + P352, P304 + P340, P305 + P351 + P338, P319, P321, P330, P332 + P317, P337 + P317, P362 + P364, P403 + P233, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Clotrimazole EP Impurity B?

The CAS Registry Number of Clotrimazole EP Impurity B is 23593-71-7. It is also known as Clotrimazole - Impurity B, 1-((4-Chlorophenyl)diphenylmethyl)-1H-imidazole, 1-[(4-Chlorophenyl)diphenylmethyl]-1H-imidazole.

What is the molecular formula and molecular weight of Clotrimazole EP Impurity B?

Clotrimazole EP Impurity B has the molecular formula C22H17ClN2 and a molecular weight of 344.8 g/mol. Its IUPAC name is 1-[(4-chlorophenyl)-diphenylmethyl]imidazole.

What is Clotrimazole EP Impurity B used for?

Clotrimazole EP Impurity B is supplied as a characterised reference material related to Clotrimazole. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Clotrimazole EP Impurity B can I order?

We supply Clotrimazole EP Impurity B in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Clotrimazole EP Impurity B?

Yes. Every lot of Clotrimazole EP Impurity B is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Clotrimazole EP Impurity B be shipped internationally?

Yes. Clotrimazole EP Impurity B is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.