3,3`-(Pyrimidine-2,4-diyl)bis(1-methyl-1H-ind… 2364486-24-6

About 3,3`-(Pyrimidine-2,4-diyl)bis(1-methyl-1H-indole)

3,3`-(Pyrimidine-2,4-diyl)bis(1-methyl-1H-indole) is a process intermediate or related compound of Osimertinib carrying the CAS registry number 2364486-24-6. Formula C22H18N4, molecular weight 338.4 g/mol. The IUPAC name is 1-methyl-3-[2-(1-methylindol-3-yl)pyrimidin-4-yl]indole.

The product is provided as a solid. Keep the vial tightly closed, protected from light and humidity, at the temperature stated on the Certificate of Analysis. Good laboratory practice and suitable PPE are recommended during handling.

Process chemists and analysts use it when developing synthetic routes to Osimertinib, tracking process-related impurities and validating analytical methods. Our customers for this product work in pharmaceutical manufacturing and academic and industrial research.

We offer 3,3`-(Pyrimidine-2,4-diyl)bis(1-methyl-1H-indole) in 10 mg, 25 mg, 50 mg and 100 mg packs with a batch-specific COA, and ship to customers worldwide. A Safety Data Sheet (SDS) and technical specifications are available on request.

Typical applications

API route development
Impurity fate & purge studies
Analytical method development

Industries

Related to Osimertinib

View every impurity, metabolite and intermediate we list for Osimertinib.

Osimertinib impurities

Specifications & identifiers

Chemical identifiers
Product name	3,3`-(Pyrimidine-2,4-diyl)bis(1-methyl-1H-indole)
Catalogue No.	VQ-049358
CAS Number	2364486-24-6
IUPAC name	1-methyl-3-[2-(1-methylindol-3-yl)pyrimidin-4-yl]indole
Molecular formula	C₂₂H₁₈N₄
Molecular weight	338.4 g/mol
Exact mass	338.1531
HSN code	2933
InChIKey	FQTFOBLOFTWVLF-UHFFFAOYSA-N
SMILES	CN1C=C(C2=CC=CC=C21)C3=NC(=NC=C3)C4=CN(C5=CC=CC=C54)C
PubChem CID	169446029

Physical properties
Physical form	Solid
LogP (XLogP3)	3.7
H-bond donors / acceptors	0 / 2
TPSA	35.6 Å²

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of 3,3`-(Pyrimidine-2,4-diyl)bis(1-methyl-1H-indole)?

The CAS Registry Number of 3,3`-(Pyrimidine-2,4-diyl)bis(1-methyl-1H-indole) is 2364486-24-6.

What is the molecular formula and molecular weight of 3,3`-(Pyrimidine-2,4-diyl)bis(1-methyl-1H-indole)?

3,3`-(Pyrimidine-2,4-diyl)bis(1-methyl-1H-indole) has the molecular formula C22H18N4 and a molecular weight of 338.4 g/mol. Its IUPAC name is 1-methyl-3-[2-(1-methylindol-3-yl)pyrimidin-4-yl]indole.

What is 3,3`-(Pyrimidine-2,4-diyl)bis(1-methyl-1H-indole) used for?

3,3`-(Pyrimidine-2,4-diyl)bis(1-methyl-1H-indole) is supplied as a characterised reference material related to Osimertinib. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of 3,3`-(Pyrimidine-2,4-diyl)bis(1-methyl-1H-indole) can I order?

We supply 3,3`-(Pyrimidine-2,4-diyl)bis(1-methyl-1H-indole), in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with 3,3`-(Pyrimidine-2,4-diyl)bis(1-methyl-1H-indole)?

Yes. Every lot of 3,3`-(Pyrimidine-2,4-diyl)bis(1-methyl-1H-indole) is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can 3,3`-(Pyrimidine-2,4-diyl)bis(1-methyl-1H-indole) be shipped internationally?

Yes. We export 3,3`-(Pyrimidine-2,4-diyl)bis(1-methyl-1H-indole) worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.