21-(Acetyloxy)-17-hydroxy-pregna-4,6-diene-3,… 2435-02-1

About 21-(Acetyloxy)-17-hydroxy-pregna-4,6-diene-3,11,20-trione

21-(Acetyloxy)-17-hydroxy-pregna-4,6-diene-3,11,20-trione is a metabolite or degradation product of Cortisone carrying the CAS registry number 2435-02-1. The compound has the formula C23H28O6, corresponding to a molecular weight of 400.5 g/mol.

It is supplied as a solid. Keep the vial tightly closed, protected from light and humidity, at the temperature stated on the Certificate of Analysis. Handle it with standard laboratory precautions and appropriate personal protective equipment.

Analytical teams use this compound to identify metabolites and degradants of Cortisone, to validate stability-indicating methods (AMV) and to support QC and regulatory filings. Typical end-use sectors are pharmaceutical manufacturing and academic and industrial research.

Standard pack sizes are 10 mg, 25 mg, 50 mg and 100 mg, and every batch ships with a Certificate of Analysis (COA) and we export worldwide.

Typical applications

Metabolite identification
Stability-indicating methods
Impurity profiling

Industries

Related to Cortisone

View every impurity, metabolite and intermediate we list for Cortisone.

Cortisone impurities

Specifications & identifiers

Chemical identifiers
Product name	21-(Acetyloxy)-17-hydroxy-pregna-4,6-diene-3,11,20-trione
Catalogue No.	VQ-036443
CAS Number	2435-02-1
IUPAC name	[2-[(8S,9S,13S,14S,17R)-17-hydroxy-10,13-dimethyl-3,11-dioxo-1,2,8,9,12,14,15,16-octahydrocyclopenta[a]phenanthren-17-yl]-2-oxoethyl] acetate
Molecular formula	C₂₃H₂₈O₆
Molecular weight	400.5 g/mol
Exact mass	400.1886
Grade	Reference Standard
HSN code	38229090
InChIKey	QDQSHYPJQHVPIE-LCLBLDJOSA-N
SMILES	CC(=O)OCC(=O)[C@]1(CC[C@@H]2[C@@]1(CC(=O)[C@H]3[C@H]2C=CC4=CC(=O)CCC34C)C)O
PubChem CID	167995474

Physical properties
Physical form	Solid
LogP (XLogP3)	1.9
H-bond donors / acceptors	1 / 6
TPSA	97.7 Å²

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of 21-(Acetyloxy)-17-hydroxy-pregna-4,6-diene-3,11,20-trione?

The CAS Registry Number of 21-(Acetyloxy)-17-hydroxy-pregna-4,6-diene-3,11,20-trione is 2435-02-1.

What is the molecular formula and molecular weight of 21-(Acetyloxy)-17-hydroxy-pregna-4,6-diene-3,11,20-trione?

21-(Acetyloxy)-17-hydroxy-pregna-4,6-diene-3,11,20-trione has the molecular formula C23H28O6 and a molecular weight of 400.5 g/mol. Its IUPAC name is [2-[(8S,9S,13S,14S,17R)-17-hydroxy-10,13-dimethyl-3,11-dioxo-1,2,8,9,12,14,15,16-octahydrocyclopenta[a]phenanthren-17-yl]-2-oxoethyl] acetate.

What is 21-(Acetyloxy)-17-hydroxy-pregna-4,6-diene-3,11,20-trione used for?

21-(Acetyloxy)-17-hydroxy-pregna-4,6-diene-3,11,20-trione is supplied as a characterised reference material related to Cortisone. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of 21-(Acetyloxy)-17-hydroxy-pregna-4,6-diene-3,11,20-trione can I order?

We supply 21-(Acetyloxy)-17-hydroxy-pregna-4,6-diene-3,11,20-trione in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with 21-(Acetyloxy)-17-hydroxy-pregna-4,6-diene-3,11,20-trione?

Yes. Every lot of 21-(Acetyloxy)-17-hydroxy-pregna-4,6-diene-3,11,20-trione is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can 21-(Acetyloxy)-17-hydroxy-pregna-4,6-diene-3,11,20-trione be shipped internationally?

Yes. We export 21-(Acetyloxy)-17-hydroxy-pregna-4,6-diene-3,11,20-trione worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.