Epirubicin EP Impurity A

Name: Epirubicin EP Impurity A
Brand: Vaqora Chemicals
SKU: VQ-025561

About Epirubicin EP Impurity A

Listed under CAS 24385-10-2, Epirubicin EP Impurity A is a pharmacopeial impurity of Doxorubicin available from Vaqora Chemicals. The compound has the formula C21H18O9, corresponding to a molecular weight of 414.4 g/mol. Its systematic (IUPAC) name is (7S,9S)-6,7,9,11-tetrahydroxy-9-(2-hydroxyacetyl)-4-methoxy-8,10-dihydro-7H-tetracene-5,12-dione. Alternative names: Doxorubicinone and Doxorubicin EP Impurity D.

It is supplied as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. It carries the GHS signal word “Danger” with 6 hazard statements. Review the Safety Data Sheet before use.

This Doxorubicin impurity supports analytical method development and validation (AMV), batch release testing and the impurity sections of ANDA and DMF filings. Typical end-use sectors are pharmaceutical manufacturing and academic and industrial research.

Standard pack sizes are 10 mg, 25 mg, 50 mg and 100 mg, and every batch ships with a Certificate of Analysis (COA) and we export worldwide.

Typical applications

Pharmacopeial method verification
Impurity profiling
QC release testing
ANDA / DMF filings

Industries

Related to Doxorubicin

View every impurity, metabolite and intermediate we list for Doxorubicin.

Doxorubicin impurities

Grade guides

Specifications & identifiers

Chemical identifiers
Product name	Epirubicin EP Impurity A
Catalogue No.	VQ-025561
CAS Number	24385-10-2
IUPAC name	(7S,9S)-6,7,9,11-tetrahydroxy-9-(2-hydroxyacetyl)-4-methoxy-8,10-dihydro-7H-tetracene-5,12-dione
Molecular formula	C₂₁H₁₈O₉
Molecular weight	414.4 g/mol
Exact mass	414.0951
Grade	Reference Standard
HSN code	38229090
InChIKey	IBZGBXXTIGCACK-CWKPULSASA-N
SMILES	COC1=CC=CC2=C1C(=O)C3=C(C4=C(C[C@](C[C@@H]4O)(C(=O)CO)O)C(=C3C2=O)O)O
PubChem CID	72401

Physical properties
Physical form	Solid
LogP (XLogP3)	1.6
H-bond donors / acceptors	5 / 9
TPSA	162 Å²
Synonyms	Doxorubicinone, Doxorubicin EP Impurity D, Doxorubicin Hydrochloride - Impurity D, Epirubicin Hydrochloride - Impurity A, Adriamycinone, Adriamycin aglycone, Doxorubicin aglycone, (7S,9S)-9-glycoloyl-6,7,9,11-tetrahydroxy-4-methoxy-8,10-dihydro-7H-tetracene-5,12-quinone, (7S,9S)-9-glycoloyl-6,7,9,11-tetrahydroxy-4-methoxy-8,10-dihydro-7H

Safety & hazard information (GHS)

Toxic

Health hazard

Signal word: Danger

Hazard statements

H301Toxic if swallowed
H311Toxic in contact with skin
H331Toxic if inhaled
H340May cause genetic defects
H350May cause cancer
H360May damage fertility or the unborn child

Precautionary statements: P203, P261, P262, P264, P270, P271, P280, P301 + P316, P302 + P352, P304 + P340, P316, P318, P321, P330, P361 + P364, P403 + P233, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Epirubicin EP Impurity A?

The CAS Registry Number of Epirubicin EP Impurity A is 24385-10-2. It is also known as Doxorubicinone, Doxorubicin EP Impurity D, Doxorubicin Hydrochloride - Impurity D.

What is the molecular formula and molecular weight of Epirubicin EP Impurity A?

Epirubicin EP Impurity A has the molecular formula C21H18O9 and a molecular weight of 414.4 g/mol. Its IUPAC name is (7S,9S)-6,7,9,11-tetrahydroxy-9-(2-hydroxyacetyl)-4-methoxy-8,10-dihydro-7H-tetracene-5,12-dione.

What is Epirubicin EP Impurity A used for?

Epirubicin EP Impurity A is supplied as a characterised reference material related to Doxorubicin. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Epirubicin EP Impurity A can I order?

We supply Epirubicin EP Impurity A in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Epirubicin EP Impurity A?

Yes. Every lot of Epirubicin EP Impurity A is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Epirubicin EP Impurity A be shipped internationally?

Yes. Epirubicin EP Impurity A is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.