Donepezil EP Impurity G

About Donepezil EP Impurity G

Donepezil EP Impurity G is a pharmacopeial impurity of Donepezil carrying the CAS registry number 2452407-72-4. Formula C24H27NO3, molecular weight 377.5 g/mol. The IUPAC name is 2-[(1-benzyl-3,4-dihydro-2H-pyridin-4-yl)methyl]-5,6-dimethoxy-2,3-dihydroinden-1-one. It is also known as Donepezil EP Impurity G (Free base) or Donepezil Impurity G.

It is supplied as a solid. Keep the vial tightly closed, protected from light and humidity, at the temperature stated on the Certificate of Analysis. Good laboratory practice and suitable PPE are recommended during handling.

Pharmaceutical QC and development laboratories use this impurity standard of Donepezil to develop and validate HPLC methods, to set specification limits and to document impurity profiles in ANDA and DMF submissions. Typical end-use sectors are pharmaceutical manufacturing and academic and industrial research.

Available in 10 mg, 25 mg, 50 mg and 100 mg packs, Donepezil EP Impurity G is dispatched with a Certificate of Analysis (COA) to destinations worldwide.

Typical applications

Pharmacopeial method verification
Impurity profiling
QC release testing
ANDA / DMF filings

Industries

Related to Donepezil

View every impurity, metabolite and intermediate we list for Donepezil.

Donepezil impurities

Grade guides

Specifications & identifiers

Chemical identifiers
Product name	Donepezil EP Impurity G
Catalogue No.	VQ-034826
CAS Number	2452407-72-4
IUPAC name	2-[(1-benzyl-3,4-dihydro-2H-pyridin-4-yl)methyl]-5,6-dimethoxy-2,3-dihydroinden-1-one
Molecular formula	C₂₄H₂₇NO₃
Molecular weight	377.5 g/mol
Exact mass	377.1991
Grade	Reference Standard
HSN code	38229090
InChIKey	IMWZBSNYDVILDO-UHFFFAOYSA-N
SMILES	COC1=C(C=C2C(=C1)CC(C2=O)CC3CCN(C=C3)CC4=CC=CC=C4)OC
PubChem CID	70253324

Physical properties
Physical form	Solid
LogP (XLogP3)	4.4
H-bond donors / acceptors	0 / 4
TPSA	38.8 Å²

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Donepezil EP Impurity G?

The CAS Registry Number of Donepezil EP Impurity G is 2452407-72-4. It is also known as Donepezil EP Impurity G (Free base), Donepezil Hydrochloride Monohydrate - Impurity G, Donepezil Impurity G.

What is the molecular formula and molecular weight of Donepezil EP Impurity G?

Donepezil EP Impurity G has the molecular formula C24H27NO3 and a molecular weight of 377.5 g/mol. Its IUPAC name is 2-[(1-benzyl-3,4-dihydro-2H-pyridin-4-yl)methyl]-5,6-dimethoxy-2,3-dihydroinden-1-one.

What is Donepezil EP Impurity G used for?

Donepezil EP Impurity G is supplied as a characterised reference material related to Donepezil. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Donepezil EP Impurity G can I order?

We supply Donepezil EP Impurity G in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Donepezil EP Impurity G?

Yes. Every lot of Donepezil EP Impurity G is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Donepezil EP Impurity G be shipped internationally?

Yes. We export Donepezil EP Impurity G worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.