(2R,4S)-5-([1,1'-Biphenyl]-4-yl)-4-(4-isoprop… 2459446-51-4

Name: (2R,4S)-5-([1,1'-Biphenyl]-4-yl)-4-(4-isopropoxy-4-oxobutanamido)-2-methylpentanoic acid
Brand: Vaqora Chemicals
SKU: VQ-027965

About (2R,4S)-5-([1,1'-Biphenyl]-4-yl)-4-(4-isopropoxy-4-oxobutanamido)-2-methylpentanoic acid

Listed under CAS 2459446-51-4, (2R,4S)-5-([1,1'-Biphenyl]-4-yl)-4-(4-isopropoxy-4-oxobutanamido)-2-methylpentanoic acid is an impurity of Sacubitril available from Vaqora Chemicals. With the molecular formula C25H31NO5, it has a molar mass of 425.5 g/mol. The IUPAC name is (2R,4S)-2-methyl-4-[(4-oxo-4-propan-2-yloxybutanoyl)amino]-5-(4-phenylphenyl)pentanoic acid.

It is supplied as a solid. Keep the vial tightly closed, protected from light and humidity, at the temperature stated on the Certificate of Analysis. Handle it with standard laboratory precautions and appropriate personal protective equipment.

As a characterised impurity of Sacubitril, it is used for analytical method development, method validation (AMV) and routine quality-control testing, and it supports ANDA and DMF regulatory filings. It is used across pharmaceutical manufacturing and academic and industrial research.

We offer (2R,4S)-5-([1,1'-Biphenyl]-4-yl)-4-(4-isopropoxy-4-oxobutanamido)-2-methylpentanoic acid in 10 mg, 25 mg, 50 mg and 100 mg packs with a batch-specific COA, and ship to customers worldwide.

Typical applications

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Industries

Related to Sacubitril

View every impurity, metabolite and intermediate we list for Sacubitril.

Sacubitril impurities

Specifications & identifiers

Chemical identifiers
Product name	(2R,4S)-5-([1,1'-Biphenyl]-4-yl)-4-(4-isopropoxy-4-oxobutanamido)-2-methylpentanoic acid
Catalogue No.	VQ-027965
CAS Number	2459446-51-4
IUPAC name	(2R,4S)-2-methyl-4-[(4-oxo-4-propan-2-yloxybutanoyl)amino]-5-(4-phenylphenyl)pentanoic acid
Molecular formula	C₂₅H₃₁NO₅
Molecular weight	425.5 g/mol
Exact mass	425.2202
Grade	Reference Standard
HSN code	38229090
InChIKey	SUSGLSGJNZTCOT-GCJKJVERSA-N
SMILES	C[C@H](C[C@@H](CC1=CC=C(C=C1)C2=CC=CC=C2)NC(=O)CCC(=O)OC(C)C)C(=O)O
PubChem CID	151910763

Physical properties
Physical form	Solid
LogP (XLogP3)	4.2
H-bond donors / acceptors	2 / 5
TPSA	92.7 Å²

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of (2R,4S)-5-([1,1'-Biphenyl]-4-yl)-4-(4-isopropoxy-4-oxobutanamido)-2-methylpentanoic acid?

The CAS Registry Number of (2R,4S)-5-([1,1'-Biphenyl]-4-yl)-4-(4-isopropoxy-4-oxobutanamido)-2-methylpentanoic acid is 2459446-51-4.

What is the molecular formula and molecular weight of (2R,4S)-5-([1,1'-Biphenyl]-4-yl)-4-(4-isopropoxy-4-oxobutanamido)-2-methylpentanoic acid?

(2R,4S)-5-([1,1'-Biphenyl]-4-yl)-4-(4-isopropoxy-4-oxobutanamido)-2-methylpentanoic acid has the molecular formula C25H31NO5 and a molecular weight of 425.5 g/mol. Its IUPAC name is (2R,4S)-2-methyl-4-[(4-oxo-4-propan-2-yloxybutanoyl)amino]-5-(4-phenylphenyl)pentanoic acid.

What is (2R,4S)-5-([1,1'-Biphenyl]-4-yl)-4-(4-isopropoxy-4-oxobutanamido)-2-methylpentanoic acid used for?

(2R,4S)-5-([1,1'-Biphenyl]-4-yl)-4-(4-isopropoxy-4-oxobutanamido)-2-methylpentanoic acid is supplied as a characterised reference material related to Sacubitril. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of (2R,4S)-5-([1,1'-Biphenyl]-4-yl)-4-(4-isopropoxy-4-oxobutanamido)-2-methylpentanoic acid can I order?

We supply (2R,4S)-5-([1,1'-Biphenyl]-4-yl)-4-(4-isopropoxy-4-oxobutanamido)-2-methylpentanoic acid in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with (2R,4S)-5-([1,1'-Biphenyl]-4-yl)-4-(4-isopropoxy-4-oxobutanamido)-2-methylpentanoic acid?

Yes. Every lot of (2R,4S)-5-([1,1'-Biphenyl]-4-yl)-4-(4-isopropoxy-4-oxobutanamido)-2-methylpentanoic acid is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can (2R,4S)-5-([1,1'-Biphenyl]-4-yl)-4-(4-isopropoxy-4-oxobutanamido)-2-methylpentanoic acid be shipped internationally?

Yes. We export (2R,4S)-5-([1,1'-Biphenyl]-4-yl)-4-(4-isopropoxy-4-oxobutanamido)-2-methylpentanoic acid worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.