Sacubitril Isopropyl ester

About Sacubitril Isopropyl ester

Sacubitril Isopropyl ester is an impurity of Sacubitril carrying the CAS registry number 2459446-53-6. The compound has the formula C27H35NO5, corresponding to a molecular weight of 453.6 g/mol. The IUPAC name is ethyl (2R,4S)-2-methyl-4-[(4-oxo-4-propan-2-yloxybutanoyl)amino]-5-(4-phenylphenyl)pentanoate.

It is supplied as a solid. Keep the vial tightly closed, protected from light and humidity, at the temperature stated on the Certificate of Analysis. Good laboratory practice and suitable PPE are recommended during handling.

This Sacubitril impurity supports analytical method development and validation (AMV), batch release testing and the impurity sections of ANDA and DMF filings. It is used across pharmaceutical manufacturing and academic and industrial research.

Available in 10 mg, 25 mg, 50 mg and 100 mg packs, Sacubitril Isopropyl ester is dispatched with a Certificate of Analysis (COA) to destinations worldwide.

Typical applications

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Industries

Related to Sacubitril

View every impurity, metabolite and intermediate we list for Sacubitril.

Sacubitril impurities

Specifications & identifiers

Chemical identifiers
Product name	Sacubitril Isopropyl ester
Catalogue No.	VQ-027964
CAS Number	2459446-53-6
IUPAC name	ethyl (2R,4S)-2-methyl-4-[(4-oxo-4-propan-2-yloxybutanoyl)amino]-5-(4-phenylphenyl)pentanoate
Molecular formula	C₂₇H₃₅NO₅
Molecular weight	453.6 g/mol
Exact mass	453.2515
Grade	Reference Standard
HSN code	38229090
InChIKey	MYOMFQNNYCRSJH-YKSBVNFPSA-N
SMILES	CCOC(=O)[C@H](C)C[C@@H](CC1=CC=C(C=C1)C2=CC=CC=C2)NC(=O)CCC(=O)OC(C)C
PubChem CID	151152765

Physical properties
Physical form	Solid
LogP (XLogP3)	4.9
H-bond donors / acceptors	1 / 5
TPSA	81.7 Å²

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Sacubitril Isopropyl ester?

The CAS Registry Number of Sacubitril Isopropyl ester is 2459446-53-6. It is also known as (2R,4S)-Ethyl 5-([1,1'-biphenyl]-4-yl)-4-(4-isopropoxy-4-oxobutanamido)-2-methylpentanoate.

What is the molecular formula and molecular weight of Sacubitril Isopropyl ester?

Sacubitril Isopropyl ester has the molecular formula C27H35NO5 and a molecular weight of 453.6 g/mol. Its IUPAC name is ethyl (2R,4S)-2-methyl-4-[(4-oxo-4-propan-2-yloxybutanoyl)amino]-5-(4-phenylphenyl)pentanoate.

What is Sacubitril Isopropyl ester used for?

Sacubitril Isopropyl ester is supplied as a characterised reference material related to Sacubitril. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Sacubitril Isopropyl ester can I order?

We supply Sacubitril Isopropyl ester in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Sacubitril Isopropyl ester?

Yes. Every lot of Sacubitril Isopropyl ester is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Sacubitril Isopropyl ester be shipped internationally?

Yes. We export Sacubitril Isopropyl ester worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.