Bosutinib Desmethyl Impurity

Name: Bosutinib Desmethyl Impurity
Brand: Vaqora Chemicals
SKU: VQ-020977

About Bosutinib Desmethyl Impurity

Bosutinib Desmethyl Impurity (CAS 2468737-92-8) is a metabolite or degradation product of Bosutinib offered by Vaqora Chemicals. Its molecular formula is C25H27Cl2N5O3 and its molecular weight is 516.4 g/mol. Its systematic (IUPAC) name is 4-(2,4-dichloro-5-hydroxyanilino)-6-methoxy-7-[3-(4-methylpiperazin-1-yl)propoxy]quinoline-3-carbonitrile. Common synonyms include 5-Hydroxy-Des-5-Methoxy Bosutinib and Bosutinib Impurity 18.

The product is provided as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. Handle it with standard laboratory precautions and appropriate personal protective equipment.

It is used in metabolite identification, stability-indicating method development and impurity profiling of Bosutinib, as well as in QC testing and ANDA/DMF documentation. Our customers for this product work in pharmaceutical manufacturing and academic and industrial research.

Standard pack sizes are 10 mg, 25 mg, 50 mg and 100 mg, and every batch ships with a Certificate of Analysis (COA) and we export worldwide.

Typical applications

Metabolite identification
Stability-indicating methods
Impurity profiling

Industries

Related to Bosutinib

View every impurity, metabolite and intermediate we list for Bosutinib.

Bosutinib impurities

Specifications & identifiers

Chemical identifiers
Product name	Bosutinib Desmethyl Impurity
Catalogue No.	VQ-020977
CAS Number	2468737-92-8
IUPAC name	4-(2,4-dichloro-5-hydroxyanilino)-6-methoxy-7-[3-(4-methylpiperazin-1-yl)propoxy]quinoline-3-carbonitrile
Molecular formula	C₂₅H₂₇Cl₂N₅O₃
Molecular weight	516.4 g/mol
Exact mass	515.1491
Grade	Reference Standard
HSN code	38229090
InChIKey	YYESZVWUYKQMLK-UHFFFAOYSA-N
SMILES	CN1CCN(CC1)CCCOC2=C(C=C3C(=C2)N=CC(=C3NC4=CC(=C(C=C4Cl)Cl)O)C#N)OC
PubChem CID	58741058

Physical properties
Physical form	Solid
LogP (XLogP3)	5.1
H-bond donors / acceptors	2 / 8
TPSA	93.9 Å²

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Bosutinib Desmethyl Impurity?

The CAS Registry Number of Bosutinib Desmethyl Impurity is 2468737-92-8. It is also known as 5-Hydroxy-Des-5-Methoxy Bosutinib, Bosutinib Impurity 18.

What is the molecular formula and molecular weight of Bosutinib Desmethyl Impurity?

Bosutinib Desmethyl Impurity has the molecular formula C25H27Cl2N5O3 and a molecular weight of 516.4 g/mol. Its IUPAC name is 4-(2,4-dichloro-5-hydroxyanilino)-6-methoxy-7-[3-(4-methylpiperazin-1-yl)propoxy]quinoline-3-carbonitrile.

What is Bosutinib Desmethyl Impurity used for?

Bosutinib Desmethyl Impurity is supplied as a characterised reference material related to Bosutinib. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Bosutinib Desmethyl Impurity can I order?

We supply Bosutinib Desmethyl Impurity in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Bosutinib Desmethyl Impurity?

Yes. Every lot of Bosutinib Desmethyl Impurity is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Bosutinib Desmethyl Impurity be shipped internationally?

Yes. We export Bosutinib Desmethyl Impurity worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.