Methyl 1-acetyl-2oxoindoline-5-carboxylate

Name: Methyl 1-acetyl-2oxoindoline-5-carboxylate
Brand: Vaqora Chemicals
SKU: VQ-049252

About Methyl 1-acetyl-2oxoindoline-5-carboxylate

Methyl 1-acetyl-2oxoindoline-5-carboxylate (CAS 247082-83-3) is an impurity of Nintedanib offered by Vaqora Chemicals. Formula C12H11NO4, molecular weight 233.22 g/mol. Its systematic (IUPAC) name is methyl 1-acetyl-2-oxo-3H-indole-5-carboxylate. It is also known as Nintedanib N-Acyl-5-carboxylate or methyl 1-acetyl-oxindole-5-carboxylate.

It is supplied as a solid. Keep the vial tightly closed, protected from light and humidity, at the temperature stated on the Certificate of Analysis. Handle it with standard laboratory precautions and appropriate personal protective equipment.

This Nintedanib impurity supports analytical method development and validation (AMV), batch release testing and the impurity sections of ANDA and DMF filings. Buyers come mainly from pharmaceutical manufacturing and academic and industrial research.

Available in 10 mg, 25 mg, 50 mg and 100 mg packs, Methyl 1-acetyl-2oxoindoline-5-carboxylate is dispatched with a Certificate of Analysis (COA) to destinations worldwide.

Typical applications

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Industries

Related to Nintedanib

View every impurity, metabolite and intermediate we list for Nintedanib.

Nintedanib impurities

Specifications & identifiers

Chemical identifiers
Product name	Methyl 1-acetyl-2oxoindoline-5-carboxylate
Catalogue No.	VQ-049252
CAS Number	247082-83-3
IUPAC name	methyl 1-acetyl-2-oxo-3H-indole-5-carboxylate
Molecular formula	C₁₂H₁₁NO₄
Molecular weight	233.22 g/mol
Exact mass	233.0688
Grade	Reference Standard
HSN code	38229090
InChIKey	PLXLACUZTXRZJP-UHFFFAOYSA-N
SMILES	CC(=O)N1C(=O)CC2=C1C=CC(=C2)C(=O)OC
PubChem CID	18614835

Physical properties
Physical form	Solid
LogP (XLogP3)	0.6
H-bond donors / acceptors	0 / 4
TPSA	63.7 Å²

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Methyl 1-acetyl-2oxoindoline-5-carboxylate?

The CAS Registry Number of Methyl 1-acetyl-2oxoindoline-5-carboxylate is 247082-83-3. It is also known as Nintedanib N-Acyl-5-carboxylate, methyl 1-acetyl-oxindole-5-carboxylate, methyl 1-acetyl-2-oxo-2,3-dihydro-1H-indole-5-carboxylate.

What is the molecular formula and molecular weight of Methyl 1-acetyl-2oxoindoline-5-carboxylate?

Methyl 1-acetyl-2oxoindoline-5-carboxylate has the molecular formula C12H11NO4 and a molecular weight of 233.22 g/mol. Its IUPAC name is methyl 1-acetyl-2-oxo-3H-indole-5-carboxylate.

What is Methyl 1-acetyl-2oxoindoline-5-carboxylate used for?

Methyl 1-acetyl-2oxoindoline-5-carboxylate is supplied as a characterised reference material related to Nintedanib. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Methyl 1-acetyl-2oxoindoline-5-carboxylate can I order?

We supply Methyl 1-acetyl-2oxoindoline-5-carboxylate in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Methyl 1-acetyl-2oxoindoline-5-carboxylate?

Yes. Every lot of Methyl 1-acetyl-2oxoindoline-5-carboxylate is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Methyl 1-acetyl-2oxoindoline-5-carboxylate be shipped internationally?

Yes. We export Methyl 1-acetyl-2oxoindoline-5-carboxylate worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.