N-Nitroso Bumetanide

Name: N-Nitroso Bumetanide
Brand: Vaqora Chemicals
SKU: VQ-006881

About N-Nitroso Bumetanide

Vaqora Chemicals supplies N-Nitroso Bumetanide, a nitrosamine impurity of Bumetanide registered under CAS number 2490432-02-3, specified at 98% purity. The compound has the formula C17H19N3O6S, corresponding to a molecular weight of 393.4 g/mol. Systematically, it is named 3-[butyl(nitroso)amino]-4-phenoxy-5-sulfamoylbenzoic acid. Common synonyms include N- Nitroso Bumetanide and N-nitroso-bumetanide.

It is supplied as a solid. Keep the vial tightly closed, protected from light and humidity, at the temperature stated on the Certificate of Analysis. It carries the GHS signal word “Warning” with 4 hazard statements. Review the Safety Data Sheet before use.

It is used as a reference standard for trace-level detection and quantitation of nitrosamine impurities by LC-MS/MS or GC-MS, supporting nitrosamine risk assessments for Bumetanide, method validation (AMV) and regulatory filings. Buyers come mainly from pharmaceutical manufacturing and academic and industrial research.

Standard pack sizes are 10 mg, 25 mg, 50 mg and 100 mg, and every batch ships with a Certificate of Analysis (COA) and we export worldwide. This item is currently in stock for prompt dispatch.

Typical applications

Nitrosamine risk assessment
Trace LC-MS/MS quantitation
Method validation (AMV)
Regulatory submissions

Industries

Related to Bumetanide

View every impurity, metabolite and intermediate we list for Bumetanide.

Bumetanide impurities

Specifications & identifiers

Chemical identifiers
Product name	N-Nitroso Bumetanide
Catalogue No.	VQ-006881
CAS Number	2490432-02-3
IUPAC name	3-[butyl(nitroso)amino]-4-phenoxy-5-sulfamoylbenzoic acid
Molecular formula	C₁₇H₁₉N₃O₆S
Molecular weight	393.4 g/mol
Exact mass	393.0995
Grade	Reference Standard
Purity / assay	98%
HSN code	38229090
InChIKey	PYLMCQWIQTYALH-UHFFFAOYSA-N
SMILES	CCCCN(C1=C(C(=CC(=C1)C(=O)O)S(=O)(=O)N)OC2=CC=CC=C2)N=O
PubChem CID	155970256

Physical properties
Physical form	Solid
LogP (XLogP3)	2.6
H-bond donors / acceptors	2 / 9
TPSA	148 Å²
Synonyms	3-(butyl(nitroso)amino)-4-phenoxy-5-sulfamoylbenzoic acid, 3-(Aminosulfonyl)-5-(butylnitrosoamino)-4-phenoxybenzoic acid, N- Nitroso Bumetanide, N-nitroso-bumetanide, Bumetanide 3-(Butyl(nitroso)amino) (1mg/mL in Methanol), Bumetanide 3-(Butyl(nitroso)amino) (1 mg/mL in Methanol), Benzoic acid, 3-(aminosulfonyl)-5-(butylnitrosoamino)-4-phenoxy-

Safety & hazard information (GHS)

Harmful / irritant

Health hazard

Signal word: Warning

Hazard statements

H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
H351Suspected of causing cancer

Precautionary statements: P203, P261, P264, P264 + P265, P271, P280, P302 + P352, P304 + P340, P305 + P351 + P338, P318, P319, P321, P332 + P317, P337 + P317, P362 + P364, P403 + P233, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of N-Nitroso Bumetanide?

The CAS Registry Number of N-Nitroso Bumetanide is 2490432-02-3. It is also known as 3-(butyl(nitroso)amino)-4-phenoxy-5-sulfamoylbenzoic acid, 3-(Aminosulfonyl)-5-(butylnitrosoamino)-4-phenoxybenzoic acid, N- Nitroso Bumetanide.

What is the molecular formula and molecular weight of N-Nitroso Bumetanide?

N-Nitroso Bumetanide has the molecular formula C17H19N3O6S and a molecular weight of 393.4 g/mol. Its IUPAC name is 3-[butyl(nitroso)amino]-4-phenoxy-5-sulfamoylbenzoic acid.

What is N-Nitroso Bumetanide used for?

N-Nitroso Bumetanide is supplied as a characterised reference material related to Bumetanide. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of N-Nitroso Bumetanide can I order?

We supply N-Nitroso Bumetanide in Reference Standard (98%) grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with N-Nitroso Bumetanide?

Yes. Every lot of N-Nitroso Bumetanide is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can N-Nitroso Bumetanide be shipped internationally?

Yes. N-Nitroso Bumetanide is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.