O-Desmethyl Indomethacin

Name: O-Desmethyl Indomethacin
Brand: Vaqora Chemicals
SKU: VQ-022853

About O-Desmethyl Indomethacin

O-Desmethyl Indomethacin (CAS 2504-32-7) is a metabolite or degradation product of Indomethacin offered by Vaqora Chemicals. Formula C18H14ClNO4, molecular weight 343.8 g/mol. Systematically, it is named 2-[1-(4-chlorobenzoyl)-5-hydroxy-2-methylindol-3-yl]acetic acid. It is also known as 5-Hydroxyindomethacin or Desmethyl-indomethacin.

The product is provided as a solid. Store the standard in its sealed vial, protected from light and moisture, and follow the storage condition printed on the COA. It carries the GHS signal word “Warning” with 3 hazard statements. Review the Safety Data Sheet before use.

It is used in metabolite identification, stability-indicating method development and impurity profiling of Indomethacin, as well as in QC testing and ANDA/DMF documentation. Our customers for this product work in pharmaceutical manufacturing and academic and industrial research.

Available in 10 mg, 25 mg, 50 mg and 100 mg packs, O-Desmethyl Indomethacin is dispatched with a Certificate of Analysis (COA) to destinations worldwide.

Typical applications

Metabolite identification
Stability-indicating methods
Impurity profiling

Industries

Related to Indomethacin

View every impurity, metabolite and intermediate we list for Indomethacin.

Indomethacin impurities

Specifications & identifiers

Chemical identifiers
Product name	O-Desmethyl Indomethacin
Catalogue No.	VQ-022853
CAS Number	2504-32-7
IUPAC name	2-[1-(4-chlorobenzoyl)-5-hydroxy-2-methylindol-3-yl]acetic acid
Molecular formula	C₁₈H₁₄ClNO₄
Molecular weight	343.8 g/mol
Exact mass	343.0611
Grade	Reference Standard
HSN code	38229090
InChIKey	KMLNWQPYFBIALN-UHFFFAOYSA-N
SMILES	CC1=C(C2=C(N1C(=O)C3=CC=C(C=C3)Cl)C=CC(=C2)O)CC(=O)O
PubChem CID	159665

Physical properties
Physical form	Solid
LogP (XLogP3)	3.9
H-bond donors / acceptors	2 / 4
TPSA	79.5 Å²
Synonyms	5-Hydroxyindomethacin, Desmethyl-indomethacin, 1-(4-Chlorobenzoyl)-5-hydroxy-2-methyl-1H-indole-3-acetic Acid, 1H-Indole-3-acetic acid, 1-(4-chlorobenzoyl)-5-hydroxy-2-methyl-, Indole-3-acetic acid, 1-(p-chlorobenzoyl)-5-hydroxy-2-methyl-, Demethylindomethacin, 5-Hydroxy indomethacin, Desmethylindomethacin, 1-(4-chlorobenzoyl)-5-hydroxy-2-methyl-3-indoleacetic acid, 1-(p-Chlorobenzoyl)-5-hydroxy-2-methylindole-3-acetic acid, 1H-Indole-3-aceticacid, 1-(4-chlorobenzoyl)-5-hydroxy-2-methyl-

Safety & hazard information (GHS)

Harmful / irritant

Signal word: Warning

Hazard statements

H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation

Precautionary statements: P261, P264, P264 + P265, P271, P280, P302 + P352, P304 + P340, P305 + P351 + P338, P319, P321, P332 + P317, P337 + P317, P362 + P364, P403 + P233, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of O-Desmethyl Indomethacin?

The CAS Registry Number of O-Desmethyl Indomethacin is 2504-32-7. It is also known as 5-Hydroxyindomethacin, Desmethyl-indomethacin, 1-(4-Chlorobenzoyl)-5-hydroxy-2-methyl-1H-indole-3-acetic Acid.

What is the molecular formula and molecular weight of O-Desmethyl Indomethacin?

O-Desmethyl Indomethacin has the molecular formula C18H14ClNO4 and a molecular weight of 343.8 g/mol. Its IUPAC name is 2-[1-(4-chlorobenzoyl)-5-hydroxy-2-methylindol-3-yl]acetic acid.

What is O-Desmethyl Indomethacin used for?

O-Desmethyl Indomethacin is supplied as a characterised reference material related to Indomethacin. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of O-Desmethyl Indomethacin can I order?

We supply O-Desmethyl Indomethacin in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with O-Desmethyl Indomethacin?

Yes. Every lot of O-Desmethyl Indomethacin is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can O-Desmethyl Indomethacin be shipped internationally?

Yes. O-Desmethyl Indomethacin is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.