R-(+)-Nicotine

About R-(+)-Nicotine

R-(+)-Nicotine is an impurity of Nicotine Hemisulfate carrying the CAS registry number 25162-00-9. Formula C10H14N2, molecular weight 162.23 g/mol. The IUPAC name is 3-[(2R)-1-methylpyrrolidin-2-yl]pyridine. It is also known as Nicotine R-Isomer or R-(R)-Nicotine.

It is supplied as a solid. Keep the vial tightly closed, protected from light and humidity, at the temperature stated on the Certificate of Analysis. Handle it with standard laboratory precautions and appropriate personal protective equipment.

As a characterised impurity of Nicotine Hemisulfate, it is used for analytical method development, method validation (AMV) and routine quality-control testing, and it supports ANDA and DMF regulatory filings. Typical end-use sectors are pharmaceutical manufacturing and academic and industrial research.

We offer R-(+)-Nicotine in 10 mg, 25 mg, 50 mg and 100 mg packs with a batch-specific COA, and ship to customers worldwide.

Typical applications

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Industries

Related to Nicotine Hemisulfate

View every impurity, metabolite and intermediate we list for Nicotine Hemisulfate.

Nicotine Hemisulfate impurities

Specifications & identifiers

Chemical identifiers
Product name	R-(+)-Nicotine
Catalogue No.	VQ-038613
CAS Number	25162-00-9
IUPAC name	3-[(2R)-1-methylpyrrolidin-2-yl]pyridine
Molecular formula	C₁₀H₁₄N₂
Molecular weight	162.23 g/mol
Exact mass	162.1157
Grade	Reference Standard
HSN code	38229090
InChIKey	SNICXCGAKADSCV-SNVBAGLBSA-N
SMILES	CN1CCC[C@@H]1C2=CN=CC=C2
PubChem CID	157672

Physical properties
Physical form	Solid
LogP (XLogP3)	1.2
H-bond donors / acceptors	0 / 2
TPSA	16.1 Å²
Synonyms	Nicotine R-Isomer, R-(R)-Nicotine, (+)-Nicotine, D-Nicotine, 2'-beta-H-Nicotine, Nicotine, (+)-, Pyridine, 3-[(2R)-1-methyl-2-pyrrolidinyl]-, (R)-3-(1-Methyl-2-pyrrolidinyl)pyridine, D-(+)-Nicotine, (R)-3-(1-Methylpyrrolidin-2-yl)pyridine

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of R-(+)-Nicotine?

The CAS Registry Number of R-(+)-Nicotine is 25162-00-9. It is also known as Nicotine R-Isomer, R-(R)-Nicotine, (+)-Nicotine.

What is the molecular formula and molecular weight of R-(+)-Nicotine?

R-(+)-Nicotine has the molecular formula C10H14N2 and a molecular weight of 162.23 g/mol. Its IUPAC name is 3-[(2R)-1-methylpyrrolidin-2-yl]pyridine.

What is R-(+)-Nicotine used for?

R-(+)-Nicotine is supplied as a characterised reference material related to Nicotine Hemisulfate. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of R-(+)-Nicotine can I order?

We supply R-(+)-Nicotine in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with R-(+)-Nicotine?

Yes. Every lot of R-(+)-Nicotine is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can R-(+)-Nicotine be shipped internationally?

Yes. We export R-(+)-Nicotine worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.