Itraconazole EP Impurity E

Name: Itraconazole EP Impurity E
Brand: Vaqora Chemicals
SKU: VQ-026252

About Itraconazole EP Impurity E

Listed under CAS 252964-65-1, Itraconazole EP Impurity E is a pharmacopeial impurity of Itraconazole available from Vaqora Chemicals. Formula C35H38Cl2N8O4, molecular weight 705.6 g/mol. Alternative names: Itraconazole - Impurity E and trans-Itraconazole.

It is supplied as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. Good laboratory practice and suitable PPE are recommended during handling.

Pharmaceutical QC and development laboratories use this impurity standard of Itraconazole to develop and validate HPLC methods, to set specification limits and to document impurity profiles in ANDA and DMF submissions. Typical end-use sectors are pharmaceutical manufacturing and academic and industrial research.

Available in 10 mg, 25 mg, 50 mg and 100 mg packs, Itraconazole EP Impurity E is dispatched with a Certificate of Analysis (COA) to destinations worldwide.

Typical applications

Pharmacopeial method verification
Impurity profiling
QC release testing
ANDA / DMF filings

Industries

Related to Itraconazole

View every impurity, metabolite and intermediate we list for Itraconazole.

Itraconazole impurities

Grade guides

Specifications & identifiers

Chemical identifiers
Product name	Itraconazole EP Impurity E
Catalogue No.	VQ-026252
CAS Number	252964-65-1
IUPAC name	2-butan-2-yl-4-[4-[4-[4-[[(2R,4R)-2-(2,4-dichlorophenyl)-2-(1,2,4-triazol-1-ylmethyl)-1,3-dioxolan-4-yl]methoxy]phenyl]piperazin-1-yl]phenyl]-1,2,4-triazol-3-one
Molecular formula	C₃₅H₃₈Cl₂N₈O₄
Molecular weight	705.6 g/mol
Exact mass	704.2393
Grade	Reference Standard
HSN code	38229090
InChIKey	VHVPQPYKVGDNFY-KKHGCVKGSA-N
SMILES	CCC(C)N1C(=O)N(C=N1)C2=CC=C(C=C2)N3CCN(CC3)C4=CC=C(C=C4)OC[C@@H]5CO[C@](O5)(CN6C=NC=N6)C7=C(C=C(C=C7)Cl)Cl
PubChem CID	14179011

Physical properties
Physical form	Solid
LogP (XLogP3)	5.7
H-bond donors / acceptors	0 / 9
TPSA	101 Å²
Synonyms	Itraconazole - Impurity E, trans-Itraconazole, Itraconazole Impurity E, Itraconazole, trans-, Itraconazole, trans- (+/-)-, (2R,4R)-Itraconazole (Mixture of Diastereomers)

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Itraconazole EP Impurity E?

The CAS Registry Number of Itraconazole EP Impurity E is 252964-65-1. It is also known as Itraconazole - Impurity E, trans-Itraconazole, Itraconazole Impurity E.

What is the molecular formula and molecular weight of Itraconazole EP Impurity E?

Itraconazole EP Impurity E has the molecular formula C35H38Cl2N8O4 and a molecular weight of 705.6 g/mol.

What is Itraconazole EP Impurity E used for?

Itraconazole EP Impurity E is supplied as a characterised reference material related to Itraconazole. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Itraconazole EP Impurity E can I order?

We supply Itraconazole EP Impurity E in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Itraconazole EP Impurity E?

Yes. Every lot of Itraconazole EP Impurity E is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Itraconazole EP Impurity E be shipped internationally?

Yes. We export Itraconazole EP Impurity E worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.