Amoxicillin EP Impurity B

About Amoxicillin EP Impurity B

Amoxicillin EP Impurity B is a pharmacopeial impurity of Amoxicillin carrying the CAS registry number 26889-93-0. With the molecular formula C16H19N3O5S, it has a molar mass of 365.4 g/mol. It is also known as Amoxicillin Trihydrate - Impurity B or L-Amoxicillin.

It is supplied as a solid. Keep the vial tightly closed, protected from light and humidity, at the temperature stated on the Certificate of Analysis. It carries the GHS signal word “Danger” with 3 hazard statements. Review the Safety Data Sheet before use.

As a characterised impurity of Amoxicillin, it is used for analytical method development, method validation (AMV) and routine quality-control testing, and it supports ANDA and DMF regulatory filings. Buyers come mainly from pharmaceutical manufacturing and academic and industrial research.

We offer Amoxicillin EP Impurity B in 10 mg, 25 mg, 50 mg and 100 mg packs with a batch-specific COA, and ship to customers worldwide.

Typical applications

Pharmacopeial method verification
Impurity profiling
QC release testing
ANDA / DMF filings

Industries

Related to Amoxicillin

View every impurity, metabolite and intermediate we list for Amoxicillin.

Amoxicillin impurities

Grade guides

Specifications & identifiers

Chemical identifiers
Product name	Amoxicillin EP Impurity B
Catalogue No.	VQ-020798
CAS Number	26889-93-0
IUPAC name	(2S,5R,6R)-6-[[(2S)-2-amino-2-(4-hydroxyphenyl)acetyl]amino]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid
Molecular formula	C₁₆H₁₉N₃O₅S
Molecular weight	365.4 g/mol
Exact mass	365.1045
Grade	Reference Standard
HSN code	38229090
InChIKey	LSQZJLSUYDQPKJ-BBGACYKPSA-N
SMILES	CC1([C@@H](N2[C@H](S1)[C@@H](C2=O)NC(=O)[C@H](C3=CC=C(C=C3)O)N)C(=O)O)C
PubChem CID	32324

Physical properties
Physical form	Solid
LogP (XLogP3)	-2
H-bond donors / acceptors	4 / 7
TPSA	158 Å²

Safety & hazard information (GHS)

Harmful / irritant

Health hazard

Signal word: Danger

Hazard statements

H302Harmful if swallowed
H317May cause an allergic skin reaction
H334May cause allergy or asthma symptoms or breathing difficulties if inhaled

Precautionary statements: P233, P260, P261, P264, P270, P271, P272, P280, P284, P301 + P317, P302 + P352, P304 + P340, P321, P330, P333 + P317, P342 + P316, P362 + P364, P403, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Amoxicillin EP Impurity B?

The CAS Registry Number of Amoxicillin EP Impurity B is 26889-93-0. It is also known as Amoxicillin Trihydrate - Impurity B, L-Amoxicillin, Amoxicillin, L-.

What is the molecular formula and molecular weight of Amoxicillin EP Impurity B?

Amoxicillin EP Impurity B has the molecular formula C16H19N3O5S and a molecular weight of 365.4 g/mol. Its IUPAC name is (2S,5R,6R)-6-[[(2S)-2-amino-2-(4-hydroxyphenyl)acetyl]amino]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid.

What is Amoxicillin EP Impurity B used for?

Amoxicillin EP Impurity B is supplied as a characterised reference material related to Amoxicillin. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Amoxicillin EP Impurity B can I order?

We supply Amoxicillin EP Impurity B in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Amoxicillin EP Impurity B?

Yes. Every lot of Amoxicillin EP Impurity B is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Amoxicillin EP Impurity B be shipped internationally?

Yes. Amoxicillin EP Impurity B is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.