Buspirone EP Impurity I

About Buspirone EP Impurity I

Buspirone EP Impurity I is a pharmacopeial impurity of Buspirone carrying the CAS registry number 2725354-99-2. With the molecular formula C21H30ClN5O2, it has a molar mass of 419.9 g/mol. The IUPAC name is 8-[4-[4-(5-chloropyrimidin-2-yl)piperazin-1-yl]butyl]-8-azaspiro[4.5]decane-7,9-dione. Common synonyms include Buspirone Hydrochloride Impurity I and Buspirone Hydrochloride - Impurity I.

It is supplied as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. It carries the GHS signal word “Warning” with 1 hazard statement. Review the Safety Data Sheet before use.

Pharmaceutical QC and development laboratories use this impurity standard of Buspirone to develop and validate HPLC methods, to set specification limits and to document impurity profiles in ANDA and DMF submissions. Our customers for this product work in pharmaceutical manufacturing and academic and industrial research.

Available in 10 mg, 25 mg, 50 mg and 100 mg packs, Buspirone EP Impurity I is dispatched with a Certificate of Analysis (COA) to destinations worldwide.

Typical applications

Pharmacopeial method verification
Impurity profiling
QC release testing
ANDA / DMF filings

Industries

Related to Buspirone

View every impurity, metabolite and intermediate we list for Buspirone.

Buspirone impurities

Grade guides

Specifications & identifiers

Chemical identifiers
Product name	Buspirone EP Impurity I
Catalogue No.	VQ-021936
CAS Number	2725354-99-2
IUPAC name	8-[4-[4-(5-chloropyrimidin-2-yl)piperazin-1-yl]butyl]-8-azaspiro[4.5]decane-7,9-dione
Molecular formula	C₂₁H₃₀ClN₅O₂
Molecular weight	419.9 g/mol
Exact mass	419.2088
Grade	Reference Standard
HSN code	38229090
InChIKey	IPKKCBWQMPTCKP-UHFFFAOYSA-N
SMILES	C1CCC2(C1)CC(=O)N(C(=O)C2)CCCCN3CCN(CC3)C4=NC=C(C=N4)Cl
PubChem CID	129318579

Physical properties
Physical form	Solid
LogP (XLogP3)	3.3
H-bond donors / acceptors	0 / 6
TPSA	69.6 Å²
Synonyms	Buspirone Hydrochloride Impurity I, Buspirone Hydrochloride - Impurity I, Buspirone Chlorobuspirone, 5-Chloro Buspirone, 8-[4-[4-(5-Chloro-2-pyrimidinyl)-1-piperazinyl]butyl]-8-azaspiro[4.5]decane-7,9-dione, 8-Azaspiro[4.5]decane-7,9-dione, 8-[4-[4-(5-chloro-2-pyrimidinyl)-1-piperazinyl]butyl]-

Safety & hazard information (GHS)

Harmful / irritant

Signal word: Warning

Hazard statements

H302Harmful if swallowed

Precautionary statements: P264, P270, P301 + P317, P330, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Buspirone EP Impurity I?

The CAS Registry Number of Buspirone EP Impurity I is 2725354-99-2. It is also known as Buspirone Hydrochloride Impurity I, Buspirone Hydrochloride - Impurity I, Buspirone Chlorobuspirone.

What is the molecular formula and molecular weight of Buspirone EP Impurity I?

Buspirone EP Impurity I has the molecular formula C21H30ClN5O2 and a molecular weight of 419.9 g/mol. Its IUPAC name is 8-[4-[4-(5-chloropyrimidin-2-yl)piperazin-1-yl]butyl]-8-azaspiro[4.5]decane-7,9-dione.

What is Buspirone EP Impurity I used for?

Buspirone EP Impurity I is supplied as a characterised reference material related to Buspirone. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Buspirone EP Impurity I can I order?

We supply Buspirone EP Impurity I in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Buspirone EP Impurity I?

Yes. Every lot of Buspirone EP Impurity I is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Buspirone EP Impurity I be shipped internationally?

Yes. Buspirone EP Impurity I is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.