Cis-5-Norbornene-exo-2,3-dicarboxylic anhydri… 2746-19-2

Name: Cis-5-Norbornene-exo-2,3-dicarboxylic anhydride
Brand: Vaqora Chemicals
SKU: VQ-032505

About Cis-5-Norbornene-exo-2,3-dicarboxylic anhydride

Cis-5-Norbornene-exo-2,3-dicarboxylic anhydride (CAS 2746-19-2) is an impurity of Lurasidone offered by Vaqora Chemicals. Formula C9H8O3, molecular weight 164.16 g/mol. Its systematic (IUPAC) name is (1R,2R,6S,7S)-4-oxatricyclo[5.2.1.02,6]dec-8-ene-3,5-dione. Common synonyms include Cis-Norbornene-exo-2,3-dicarboxylic Anhydride and Himic anhydride.

The product is provided as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. The GHS classification uses the signal word “Danger”, so appropriate gloves, eye protection and ventilation are recommended.

Pharmaceutical QC and development laboratories use this impurity standard of Lurasidone to develop and validate HPLC methods, to set specification limits and to document impurity profiles in ANDA and DMF submissions. Our customers for this product work in pharmaceutical manufacturing and academic and industrial research.

Available in 10 mg, 25 mg, 50 mg and 100 mg packs, Cis-5-Norbornene-exo-2,3-dicarboxylic anhydride is dispatched with a Certificate of Analysis (COA) to destinations worldwide.

Typical applications

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Industries

Related to Lurasidone

View every impurity, metabolite and intermediate we list for Lurasidone.

Lurasidone impurities

Specifications & identifiers

Chemical identifiers
Product name	Cis-5-Norbornene-exo-2,3-dicarboxylic anhydride
Catalogue No.	VQ-032505
CAS Number	2746-19-2
IUPAC name	(1R,2R,6S,7S)-4-oxatricyclo[5.2.1.02,6]dec-8-ene-3,5-dione
Molecular formula	C₉H₈O₃
Molecular weight	164.16 g/mol
Exact mass	164.0473
Grade	Reference Standard
HSN code	38229090
InChIKey	KNDQHSIWLOJIGP-RNGGSSJXSA-N
SMILES	C1[C@@H]2C=C[C@H]1[C@H]3[C@@H]2C(=O)OC3=O
PubChem CID	637794

Physical properties
Physical form	Solid
LogP (XLogP3)	0.7
H-bond donors / acceptors	0 / 3
TPSA	43.4 Å²
Synonyms	Cis-Norbornene-exo-2,3-dicarboxylic Anhydride, Himic anhydride, 4,7-Methanoisobenzofuran-1,3-dione, 3a,4,7,7a-tetrahydro-, (3aR,4R,7S,7aS)-rel-, exo-3,6-Methylene-1,2,3,6-tetrahydrophthalic anhydride, (1alpha,2alpha,3beta,6beta)-1,2,3,6-tetrahydro-3,6-methanophthalic anhydride, (3aR,4R,7S,7aS)-rel-3a,4,7,7a-Tetrahydro-4,7-methanoisobenzofuran-1,3-dione, (1S,2S,6R,7R)-4-oxatricyclo[5.2.1.02,6]dec-8-ene-3,5-dione, 4,7-Methanoisobenzofuran-1,3-dione, 3a,4,7,7a-tetrahydro-,(3aR,4R,7S,7aS)-rel-, (3aR,4R,7S,7AS)-3a,4,7,7a-tetrahydro-4,7-methanoisobenzofuran-1,3-dione, exo-5-Norbornene-2,3-dicarboxylic anhydride, endicanhydride

Safety & hazard information (GHS)

Corrosive

Health hazard

Signal word: Danger

Hazard statements

H317May cause an allergic skin reaction
H318Causes serious eye damage
H334May cause allergy or asthma symptoms or breathing difficulties if inhaled

Precautionary statements: P233, P260, P261, P264 + P265, P271, P272, P280, P284, P302 + P352, P304 + P340, P305 + P354 + P338, P317, P321, P333 + P317, P342 + P316, P362 + P364, P403, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Cis-5-Norbornene-exo-2,3-dicarboxylic anhydride?

The CAS Registry Number of Cis-5-Norbornene-exo-2,3-dicarboxylic anhydride is 2746-19-2. It is also known as Cis-Norbornene-exo-2,3-dicarboxylic Anhydride, Himic anhydride, 4,7-Methanoisobenzofuran-1,3-dione, 3a,4,7,7a-tetrahydro-, (3aR,4R,7S,7aS)-rel-.

What is the molecular formula and molecular weight of Cis-5-Norbornene-exo-2,3-dicarboxylic anhydride?

Cis-5-Norbornene-exo-2,3-dicarboxylic anhydride has the molecular formula C9H8O3 and a molecular weight of 164.16 g/mol. Its IUPAC name is (1R,2R,6S,7S)-4-oxatricyclo[5.2.1.02,6]dec-8-ene-3,5-dione.

What is Cis-5-Norbornene-exo-2,3-dicarboxylic anhydride used for?

Cis-5-Norbornene-exo-2,3-dicarboxylic anhydride is supplied as a characterised reference material related to Lurasidone. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Cis-5-Norbornene-exo-2,3-dicarboxylic anhydride can I order?

We supply Cis-5-Norbornene-exo-2,3-dicarboxylic anhydride in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Cis-5-Norbornene-exo-2,3-dicarboxylic anhydride?

Yes. Every lot of Cis-5-Norbornene-exo-2,3-dicarboxylic anhydride is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Cis-5-Norbornene-exo-2,3-dicarboxylic anhydride be shipped internationally?

Yes. Cis-5-Norbornene-exo-2,3-dicarboxylic anhydride is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.