Ticagrelor

About Ticagrelor

Ticagrelor is a high-purity reference standard of Ticagrelor carrying the CAS registry number 274693-27-5. Formula C23H28F2N6O4S, molecular weight 522.6 g/mol. Common synonyms include AR-C 126532XX and Brilinta.

It is supplied as a solid. Store the standard in its sealed vial, protected from light and moisture, and follow the storage condition printed on the COA. It carries the GHS signal word “Warning” with 2 hazard statements. Review the Safety Data Sheet before use.

Laboratories use this Ticagrelor standard for identity and assay testing, system suitability checks and method validation supporting ANDA and DMF filings. Buyers come mainly from pharmaceutical manufacturing and academic and industrial research.

Available in 10 mg, 25 mg, 50 mg and 100 mg packs, Ticagrelor is dispatched with a Certificate of Analysis (COA) to destinations worldwide.

Typical applications

Identification & assay
Method development & validation
QC reference material

Industries

Related to Ticagrelor

View every impurity, metabolite and intermediate we list for Ticagrelor.

Ticagrelor impurities

Specifications & identifiers

Chemical identifiers
Product name	Ticagrelor
Catalogue No.	VQ-007798
CAS Number	274693-27-5
Other CAS	1465929-42-3
IUPAC name	(1S,2S,3R,5S)-3-[7-[[(1R,2S)-2-(3,4-difluorophenyl)cyclopropyl]amino]-5-propylsulfanyltriazolo[4,5-d]pyrimidin-3-yl]-5-(2-hydroxyethoxy)cyclopentane-1,2-diol
Molecular formula	C₂₃H₂₈F₂N₆O₄S
Molecular weight	522.6 g/mol
Exact mass	522.1861
Grade	Reference Standard
HSN code	38229090
InChIKey	OEKWJQXRCDYSHL-FNOIDJSQSA-N
SMILES	CCCSC1=NC(=C2C(=N1)N(N=N2)[C@@H]3C[C@@H]([C@H]([C@H]3O)O)OCCO)N[C@@H]4C[C@H]4C5=CC(=C(C=C5)F)F
PubChem CID	9871419

Physical properties
Physical form	Solid
LogP (XLogP3)	2
H-bond donors / acceptors	4 / 12
TPSA	164 Å²
Synonyms	AR-C 126532XX, Brilinta, Brilique, Possia, Triafluocyl, AZD-6140, AR-C126532XX, AZD 6140, Ticagrelor Form, Ticagrelor CRS, Brilinta (TN), Ticagrelor (Standard)

Safety & hazard information (GHS)

Harmful / irritant

Environmental hazard

Signal word: Warning

Hazard statements

H319Causes serious eye irritation
H411Toxic to aquatic life with long lasting effects

Precautionary statements: P264 + P265, P273, P280, P305 + P351 + P338, P337 + P317, P391, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Ticagrelor?

The CAS Registry Number of Ticagrelor is 274693-27-5. It is also known as AR-C 126532XX, Brilinta, Brilique.

What is the molecular formula and molecular weight of Ticagrelor?

Ticagrelor has the molecular formula C23H28F2N6O4S and a molecular weight of 522.6 g/mol. Its IUPAC name is (1S,2S,3R,5S)-3-[7-[[(1R,2S)-2-(3,4-difluorophenyl)cyclopropyl]amino]-5-propylsulfanyltriazolo[4,5-d]pyrimidin-3-yl]-5-(2-hydroxyethoxy)cyclopentane-1,2-diol.

What is Ticagrelor used for?

Ticagrelor is supplied as a characterised reference material related to Ticagrelor. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Ticagrelor can I order?

We supply Ticagrelor in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Ticagrelor?

Yes. Every lot of Ticagrelor is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Ticagrelor be shipped internationally?

Yes. Ticagrelor is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.