4-Hydroxybenzaldehyde-d4

Name: 4-Hydroxybenzaldehyde-d4
Brand: Vaqora Chemicals
SKU: VQ-035991

About 4-Hydroxybenzaldehyde-d4

4-Hydroxybenzaldehyde-d4 (CAS 284474-52-8) is a stable isotope labelled analogue related to Bisoprolol offered by Vaqora Chemicals. The compound has the formula C7H6O2, corresponding to a molecular weight of 126.15 g/mol. Systematically, it is named 2,3,5,6-tetradeuterio-4-hydroxybenzaldehyde. Alternative names: 4-Hydroxybenzaldehyde-2,3,5,6-d4 and p-Hydroxybenzaldehyde-d4.

The product is provided as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. Under GHS it is labelled “Warning”, so handle it with suitable PPE and consult the SDS.

This isotope-labelled compound is used as an internal standard for LC-MS and LC-MS/MS quantitation of Bisoprolol and related analytes in bioanalytical, pharmacokinetic and impurity studies. It is used across pharmaceutical manufacturing and academic and industrial research.

Standard pack sizes are 10 mg, 25 mg, 50 mg and 100 mg, and every batch ships with a Certificate of Analysis (COA) and we export worldwide.

Typical applications

LC-MS/MS internal standard
Bioanalytical quantitation
Pharmacokinetic studies

Industries

Related to Bisoprolol

View every impurity, metabolite and intermediate we list for Bisoprolol.

Bisoprolol impurities

Grade guides

Specifications & identifiers

Chemical identifiers
Product name	4-Hydroxybenzaldehyde-d4
Catalogue No.	VQ-035991
CAS Number	284474-52-8
IUPAC name	2,3,5,6-tetradeuterio-4-hydroxybenzaldehyde
Molecular formula	C₇H₆O₂
Molecular weight	126.15 g/mol
Exact mass	126.0619
Grade	Reference Standard
HSN code	38229090
InChIKey	RGHHSNMVTDWUBI-RHQRLBAQSA-N
SMILES	[2H]C1=C(C(=C(C(=C1C=O)[2H])[2H])O)[2H]
PubChem CID	58066911

Physical properties
Physical form	Solid
LogP (XLogP3)	1.4
H-bond donors / acceptors	1 / 2
TPSA	37.3 Å²
Synonyms	4-Hydroxybenzaldehyde-2,3,5,6-d4, p-Hydroxybenzaldehyde-d4, 4-Hydroxy(~2~H_4_)benzaldehyde, 4-hydroxy(2,3,5,6-H)benzaldehyde, 4-hydroxy(2,3,5,6-(2)H)benzaldehyde, 2,3,5,6-tetradeuterio-4-hydroxy-benzaldehyde

Safety & hazard information (GHS)

Harmful / irritant

Signal word: Warning

Hazard statements

H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation

Precautionary statements: P261, P264, P264 + P265, P271, P280, P302 + P352, P304 + P340, P305 + P351 + P338, P319, P321, P332 + P317, P337 + P317, P362 + P364, P403 + P233, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of 4-Hydroxybenzaldehyde-d4?

The CAS Registry Number of 4-Hydroxybenzaldehyde-d4 is 284474-52-8. It is also known as 4-Hydroxybenzaldehyde-2,3,5,6-d4, p-Hydroxybenzaldehyde-d4, 4-Hydroxy(~2~H_4_)benzaldehyde.

What is the molecular formula and molecular weight of 4-Hydroxybenzaldehyde-d4?

4-Hydroxybenzaldehyde-d4 has the molecular formula C7H6O2 and a molecular weight of 126.15 g/mol. Its IUPAC name is 2,3,5,6-tetradeuterio-4-hydroxybenzaldehyde.

What is 4-Hydroxybenzaldehyde-d4 used for?

4-Hydroxybenzaldehyde-d4 is supplied as a characterised reference material related to Bisoprolol. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of 4-Hydroxybenzaldehyde-d4 can I order?

We supply 4-Hydroxybenzaldehyde-d4 in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with 4-Hydroxybenzaldehyde-d4?

Yes. Every lot of 4-Hydroxybenzaldehyde-d4 is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can 4-Hydroxybenzaldehyde-d4 be shipped internationally?

Yes. 4-Hydroxybenzaldehyde-d4 is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.