2,3-Dihydro-3,5-dihydroxy-6-methyl-4-pyrone

About 2,3-Dihydro-3,5-dihydroxy-6-methyl-4-pyrone

2,3-Dihydro-3,5-dihydroxy-6-methyl-4-pyrone is an impurity of Palbociclib carrying the CAS registry number 28564-83-2. The compound has the formula C6H8O4, corresponding to a molecular weight of 144.12 g/mol. Systematically, it is named 3,5-dihydroxy-6-methyl-2,3-dihydropyran-4-one. Common synonyms include DDMP-4-one and 3,5-Dihydroxy-6-methyl-2H-pyran-4(3H)-one.

It is supplied as a solid. Store the standard in its sealed vial, protected from light and moisture, and follow the storage condition printed on the COA. The GHS classification uses the signal word “Warning”, so appropriate gloves, eye protection and ventilation are recommended.

Pharmaceutical QC and development laboratories use this impurity standard of Palbociclib to develop and validate HPLC methods, to set specification limits and to document impurity profiles in ANDA and DMF submissions. Our customers for this product work in pharmaceutical manufacturing and academic and industrial research.

Available in 10 mg, 25 mg, 50 mg and 100 mg packs, 2,3-Dihydro-3,5-dihydroxy-6-methyl-4-pyrone is dispatched with a Certificate of Analysis (COA) to destinations worldwide.

Typical applications

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Industries

Related to Palbociclib

View every impurity, metabolite and intermediate we list for Palbociclib.

Palbociclib impurities

Specifications & identifiers

Chemical identifiers
Product name	2,3-Dihydro-3,5-dihydroxy-6-methyl-4-pyrone
Catalogue No.	VQ-027365
CAS Number	28564-83-2
IUPAC name	3,5-dihydroxy-6-methyl-2,3-dihydropyran-4-one
Molecular formula	C₆H₈O₄
Molecular weight	144.12 g/mol
Exact mass	144.0423
Grade	Reference Standard
HSN code	38229090
InChIKey	VOLMSPGWNYJHQQ-UHFFFAOYSA-N
SMILES	CC1=C(C(=O)C(CO1)O)O
PubChem CID	119838

Physical properties
Physical form	Solid
LogP (XLogP3)	-0.4
H-bond donors / acceptors	2 / 4
TPSA	66.8 Å²
Synonyms	3,5-Dihydroxy-6-methyl-2,3-dihydro-4H-pyran-4-one, 2,3-Dihydro-3,5-dihydroxy-6-methyl-4h-pyran-4-one, 4H-Pyran-4-one, 2,3-dihydro-3,5-dihydroxy-6-methyl-, DDMP-4-one, 3,5-Dihydroxy-6-methyl-2H-pyran-4(3H)-one, 3,5-dihydroxy-6-methyl-3,4-dihydro-2H-pyran-4-one, 3-Hydroxy-2,3-dihydromaltol, 2,3-Dihydro-3,5-dihydroxy-6-methyl-4(H)-pyran-4-one, 35-Dihydroxy-6-methyl-2H-pyran-4(3H)-one, 3,5-dihydroxy-2-me-thyl-5,6-dihydropyran-4-one

Safety & hazard information (GHS)

Harmful / irritant

Signal word: Warning

Hazard statements

H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation

Precautionary statements: P261, P264, P264 + P265, P270, P271, P280, P301 + P317, P302 + P352, P304 + P340, P305 + P351 + P338, P319, P321, P330, P332 + P317, P337 + P317, P362 + P364, P403 + P233, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of 2,3-Dihydro-3,5-dihydroxy-6-methyl-4-pyrone?

The CAS Registry Number of 2,3-Dihydro-3,5-dihydroxy-6-methyl-4-pyrone is 28564-83-2. It is also known as 3,5-Dihydroxy-6-methyl-2,3-dihydro-4H-pyran-4-one, 2,3-Dihydro-3,5-dihydroxy-6-methyl-4h-pyran-4-one, 4H-Pyran-4-one, 2,3-dihydro-3,5-dihydroxy-6-methyl-.

What is the molecular formula and molecular weight of 2,3-Dihydro-3,5-dihydroxy-6-methyl-4-pyrone?

2,3-Dihydro-3,5-dihydroxy-6-methyl-4-pyrone has the molecular formula C6H8O4 and a molecular weight of 144.12 g/mol. Its IUPAC name is 3,5-dihydroxy-6-methyl-2,3-dihydropyran-4-one.

What is 2,3-Dihydro-3,5-dihydroxy-6-methyl-4-pyrone used for?

2,3-Dihydro-3,5-dihydroxy-6-methyl-4-pyrone is supplied as a characterised reference material related to Palbociclib. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of 2,3-Dihydro-3,5-dihydroxy-6-methyl-4-pyrone can I order?

We supply 2,3-Dihydro-3,5-dihydroxy-6-methyl-4-pyrone in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with 2,3-Dihydro-3,5-dihydroxy-6-methyl-4-pyrone?

Yes. Every lot of 2,3-Dihydro-3,5-dihydroxy-6-methyl-4-pyrone is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can 2,3-Dihydro-3,5-dihydroxy-6-methyl-4-pyrone be shipped internationally?

Yes. 2,3-Dihydro-3,5-dihydroxy-6-methyl-4-pyrone is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.