Choline-d4 Chloride

About Choline-d4 Chloride

Choline-d4 Chloride is a stable isotope labelled analogue related to Choline carrying the CAS registry number 285979-70-6. With the molecular formula C5H14ClNO, it has a molar mass of 143.65 g/mol. Systematically, it is named trimethyl-(1,1,2,2-tetradeuterio-2-hydroxyethyl)azanium chloride. It is also known as Choline-1,1,2,2 D4 Chloride or TMIH-0149.

It is supplied as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. Good laboratory practice and suitable PPE are recommended during handling.

This isotope-labelled compound is used as an internal standard for LC-MS and LC-MS/MS quantitation of Choline and related analytes in bioanalytical, pharmacokinetic and impurity studies. It is used across pharmaceutical manufacturing and academic and industrial research.

Standard pack sizes are 10 mg, 25 mg, 50 mg and 100 mg, and every batch ships with a Certificate of Analysis (COA) and we export worldwide.

Typical applications

LC-MS/MS internal standard
Bioanalytical quantitation
Pharmacokinetic studies

Industries

Related to Choline

View every impurity, metabolite and intermediate we list for Choline.

Choline impurities

Grade guides

Specifications & identifiers

Chemical identifiers
Product name	Choline-d4 Chloride
Catalogue No.	VQ-041248
CAS Number	285979-70-6
IUPAC name	trimethyl-(1,1,2,2-tetradeuterio-2-hydroxyethyl)azanium chloride
Molecular formula	C₅H₁₄ClNO
Molecular weight	143.65 g/mol
Exact mass	143.1015
Grade	Reference Standard
HSN code	38229090
InChIKey	SGMZJAMFUVOLNK-HGFPCDIYSA-M
SMILES	[2H]C([2H])(C([2H])([2H])O)[N+](C)(C)C.[Cl-]
PubChem CID	71309026

Physical properties
Physical form	Solid
H-bond donors / acceptors	1 / 2
TPSA	20.2 Å²

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Choline-d4 Chloride?

The CAS Registry Number of Choline-d4 Chloride is 285979-70-6. It is also known as Choline-1,1,2,2 D4 Chloride, TMIH-0149, 2-Hydroxy-N,N,N-trimethylethan-1,1,2,2-d4-aminium chloride.

What is the molecular formula and molecular weight of Choline-d4 Chloride?

Choline-d4 Chloride has the molecular formula C5H14ClNO and a molecular weight of 143.65 g/mol. Its IUPAC name is trimethyl-(1,1,2,2-tetradeuterio-2-hydroxyethyl)azanium chloride.

What is Choline-d4 Chloride used for?

Choline-d4 Chloride is supplied as a characterised reference material related to Choline. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Choline-d4 Chloride can I order?

We supply Choline-d4 Chloride in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Choline-d4 Chloride?

Yes. Every lot of Choline-d4 Chloride is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Choline-d4 Chloride be shipped internationally?

Yes. We export Choline-d4 Chloride worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.