2-Chloro-2-(phenylhydrazono)acetic Acid Ethyl… 28663-68-5

Name: 2-Chloro-2-(phenylhydrazono)acetic Acid Ethyl Ester
Brand: Vaqora Chemicals
SKU: VQ-024327

About 2-Chloro-2-(phenylhydrazono)acetic Acid Ethyl Ester

2-Chloro-2-(phenylhydrazono)acetic Acid Ethyl Ester is an impurity of Apixaban carrying the CAS registry number 28663-68-5. Its molecular formula is C10H11ClN2O2 and its molecular weight is 226.66 g/mol. The IUPAC name is ethyl (2Z)-2-chloro-2-(phenylhydrazinylidene)acetate. Common synonyms include Ethyl 2-chloro-2-(2-phenylhydrazono)acetate and Ethyl 2-chloro-2-(phenylhydrazono)acetate.

The product is provided as a solid. Keep the vial tightly closed, protected from light and humidity, at the temperature stated on the Certificate of Analysis. It carries the GHS signal word “Warning” with 3 hazard statements. Review the Safety Data Sheet before use.

This Apixaban impurity supports analytical method development and validation (AMV), batch release testing and the impurity sections of ANDA and DMF filings. Typical end-use sectors are pharmaceutical manufacturing and academic and industrial research.

Vaqora Chemicals supplies 2-Chloro-2-(phenylhydrazono)acetic Acid Ethyl Ester in 10 mg, 25 mg, 50 mg and 100 mg packs, each shipped with a Certificate of Analysis (COA), and exports worldwide.

Typical applications

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Industries

Related to Apixaban

View every impurity, metabolite and intermediate we list for Apixaban.

Apixaban impurities

Specifications & identifiers

Chemical identifiers
Product name	2-Chloro-2-(phenylhydrazono)acetic Acid Ethyl Ester
Catalogue No.	VQ-024327
CAS Number	28663-68-5
IUPAC name	ethyl (2Z)-2-chloro-2-(phenylhydrazinylidene)acetate
Molecular formula	C₁₀H₁₁ClN₂O₂
Molecular weight	226.66 g/mol
Exact mass	226.0509
Grade	Reference Standard
HSN code	38229090
InChIKey	LZCJYKSOIZQABU-LCYFTJDESA-N
SMILES	CCOC(=O)/C(=N/NC1=CC=CC=C1)/Cl
PubChem CID	5708313

Physical properties
Physical form	Solid
LogP (XLogP3)	4.1
H-bond donors / acceptors	1 / 4
TPSA	50.7 Å²
Synonyms	Ethyl (Z)-2-chloro-2-(2-phenylhydrazono)acetate, Ethyl 2-chloro-2-(2-phenylhydrazono)acetate, ethyl 2-chloro-2-[(E)-2-phenylhydrazono]acetate, Ethyl 2-chloro-2-(phenylhydrazono)acetate, 2-Chloro-2-(phenylhydrazono)acetic acid ethyl ether, 2-Chloro-2-(phenylhydrazono)acetic acid ethyl, Acetic acid, phenylhydrazonochloro-, ethyl ester, ethyl 2-chloro-2-phenylhydrazonoacetate, Locust bean gum from Ceratonia siliqua seeds, Ethyl (2Z)-chloro(phenylhydrazono)ethanoate #, (Z)-Ethyl2-chloro-2-(2-phenylhydrazono)acetate, ethyl (2Z)-2-chloro-2-(phenylhydrazono)acetate

Safety & hazard information (GHS)

Harmful / irritant

Signal word: Warning

Hazard statements

H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation

Precautionary statements: P261, P264, P264 + P265, P271, P280, P302 + P352, P304 + P340, P305 + P351 + P338, P319, P321, P332 + P317, P337 + P317, P362 + P364, P403 + P233, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of 2-Chloro-2-(phenylhydrazono)acetic Acid Ethyl Ester?

The CAS Registry Number of 2-Chloro-2-(phenylhydrazono)acetic Acid Ethyl Ester is 28663-68-5. It is also known as Ethyl (Z)-2-chloro-2-(2-phenylhydrazono)acetate, Ethyl 2-chloro-2-(2-phenylhydrazono)acetate, ethyl 2-chloro-2-[(E)-2-phenylhydrazono]acetate.

What is the molecular formula and molecular weight of 2-Chloro-2-(phenylhydrazono)acetic Acid Ethyl Ester?

2-Chloro-2-(phenylhydrazono)acetic Acid Ethyl Ester has the molecular formula C10H11ClN2O2 and a molecular weight of 226.66 g/mol. Its IUPAC name is ethyl (2Z)-2-chloro-2-(phenylhydrazinylidene)acetate.

What is 2-Chloro-2-(phenylhydrazono)acetic Acid Ethyl Ester used for?

2-Chloro-2-(phenylhydrazono)acetic Acid Ethyl Ester is supplied as a characterised reference material related to Apixaban. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of 2-Chloro-2-(phenylhydrazono)acetic Acid Ethyl Ester can I order?

We supply 2-Chloro-2-(phenylhydrazono)acetic Acid Ethyl Ester in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with 2-Chloro-2-(phenylhydrazono)acetic Acid Ethyl Ester?

Yes. Every lot of 2-Chloro-2-(phenylhydrazono)acetic Acid Ethyl Ester is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can 2-Chloro-2-(phenylhydrazono)acetic Acid Ethyl Ester be shipped internationally?

Yes. 2-Chloro-2-(phenylhydrazono)acetic Acid Ethyl Ester is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.