Nevirapine EP Impurity B

About Nevirapine EP Impurity B

Nevirapine EP Impurity B is a pharmacopeial impurity of Nevirapine carrying the CAS registry number 287980-84-1. Its molecular formula is C12H10N4O and its molecular weight is 226.23 g/mol. Systematically, it is named 7-methyl-2,4,9,15-tetrazatricyclo[9.4.0.03,8]pentadeca-1(11),3,5,7,12,14-hexaen-10-one. Common synonyms include Nevirapine - Impurity B and 11-Descyclopropyl nevirapine.

The product is provided as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. The GHS classification uses the signal word “Danger”, so appropriate gloves, eye protection and ventilation are recommended.

This Nevirapine impurity supports analytical method development and validation (AMV), batch release testing and the impurity sections of ANDA and DMF filings. Buyers come mainly from pharmaceutical manufacturing and academic and industrial research.

We offer Nevirapine EP Impurity B in 10 mg, 25 mg, 50 mg and 100 mg packs with a batch-specific COA, and ship to customers worldwide.

Typical applications

Pharmacopeial method verification
Impurity profiling
QC release testing
ANDA / DMF filings

Industries

Related to Nevirapine

View every impurity, metabolite and intermediate we list for Nevirapine.

Nevirapine impurities

Grade guides

Specifications & identifiers

Chemical identifiers
Product name	Nevirapine EP Impurity B
Catalogue No.	VQ-023238
CAS Number	287980-84-1
IUPAC name	7-methyl-2,4,9,15-tetrazatricyclo[9.4.0.03,8]pentadeca-1(11),3,5,7,12,14-hexaen-10-one
Molecular formula	C₁₂H₁₀N₄O
Molecular weight	226.23 g/mol
Exact mass	226.0855
Grade	Reference Standard
HSN code	38229090
InChIKey	RKCRKBSFEVQVSX-UHFFFAOYSA-N
SMILES	CC1=C2C(=NC=C1)NC3=C(C=CC=N3)C(=O)N2
PubChem CID	22399003

Physical properties
Physical form	Solid
LogP (XLogP3)	1.3
H-bond donors / acceptors	2 / 4
TPSA	66.9 Å²
Synonyms	Nevirapine - Impurity B, 11-Descyclopropyl nevirapine, Nevirapine hemihydrate specified impurity B, Nevirapine, anhydrous specified impurity B, 5,11-Dihydro-4-methyl-6H-dipyrido(3,2-b:2',3'-E)(1,4)diazepin-6-one, 6H-Dipyrido(3,2-b:2',3'-E)(1,4)diazepin-6-one, 5,11-dihydro-4-methyl-, 4-Methyl-5,11-dihydro-6H-dipyrido[3,2-b:2',3'-e][1,4]diazepin-6-one, 5,11-dihydro-4-methyl-6H-dipyrido[3,2-b:2',3'-e][1,4]diazepin-6-one, Nevirapine impurity B RS

Safety & hazard information (GHS)

Toxic

Harmful / irritant

Signal word: Danger

Hazard statements

H301Toxic if swallowed
H302Harmful if swallowed

Precautionary statements: P264, P270, P301 + P316, P301 + P317, P321, P330, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Nevirapine EP Impurity B?

The CAS Registry Number of Nevirapine EP Impurity B is 287980-84-1. It is also known as Nevirapine - Impurity B, 11-Descyclopropyl nevirapine, Nevirapine hemihydrate specified impurity B.

What is the molecular formula and molecular weight of Nevirapine EP Impurity B?

Nevirapine EP Impurity B has the molecular formula C12H10N4O and a molecular weight of 226.23 g/mol. Its IUPAC name is 7-methyl-2,4,9,15-tetrazatricyclo[9.4.0.03,8]pentadeca-1(11),3,5,7,12,14-hexaen-10-one.

What is Nevirapine EP Impurity B used for?

Nevirapine EP Impurity B is supplied as a characterised reference material related to Nevirapine. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Nevirapine EP Impurity B can I order?

We supply Nevirapine EP Impurity B in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Nevirapine EP Impurity B?

Yes. Every lot of Nevirapine EP Impurity B is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Nevirapine EP Impurity B be shipped internationally?

Yes. Nevirapine EP Impurity B is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.