Midazolam EP Impurity F

Name: Midazolam EP Impurity F
Brand: Vaqora Chemicals
SKU: VQ-035435

About Midazolam EP Impurity F

Listed under CAS 2886-65-9, Midazolam EP Impurity F is a pharmacopeial impurity of Flurazepam available from Vaqora Chemicals. With the molecular formula C15H10ClFN2O, it has a molar mass of 288.7 g/mol. Systematically, it is named 7-chloro-5-(2-fluorophenyl)-1,3-dihydro-1,4-benzodiazepin-2-one. Common synonyms include Flurazepam EP Impurity B and Flurazepam - Impurity B.

It is supplied as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. Under GHS it is labelled “Warning”, so handle it with suitable PPE and consult the SDS.

This Flurazepam impurity supports analytical method development and validation (AMV), batch release testing and the impurity sections of ANDA and DMF filings. It is used across pharmaceutical manufacturing and academic and industrial research.

Vaqora Chemicals supplies Midazolam EP Impurity F in 10 mg, 25 mg, 50 mg and 100 mg packs, each shipped with a Certificate of Analysis (COA), and exports worldwide.

Typical applications

Pharmacopeial method verification
Impurity profiling
QC release testing
ANDA / DMF filings

Industries

Related to Flurazepam

View every impurity, metabolite and intermediate we list for Flurazepam.

Flurazepam impurities

Grade guides

Specifications & identifiers

Chemical identifiers
Product name	Midazolam EP Impurity F
Catalogue No.	VQ-035435
CAS Number	2886-65-9
IUPAC name	7-chloro-5-(2-fluorophenyl)-1,3-dihydro-1,4-benzodiazepin-2-one
Molecular formula	C₁₅H₁₀ClFN₂O
Molecular weight	288.7 g/mol
Exact mass	288.0466
Grade	Reference Standard
HSN code	38229090
InChIKey	UVCOILFBWYKHHB-UHFFFAOYSA-N
SMILES	C1C(=O)NC2=C(C=C(C=C2)Cl)C(=N1)C3=CC=CC=C3F
PubChem CID	4540

Physical properties
Physical form	Solid
LogP (XLogP3)	2.7
H-bond donors / acceptors	1 / 3
TPSA	41.5 Å²
Synonyms	Flurazepam EP Impurity B, Flurazepam - Impurity B, Midazolam - Impurity F, Descarbethoxyloflazepate, 7-Chloro-5-(2-fluorophenyl)-1H-benzo[e][1,4]diazepin-2(3H)-one, 2H-1,4-Benzodiazepin-2-one, 7-chloro-5-(2-fluorophenyl)-1,3-dihydro-, 7-Chloro-5-(2-fluorophenyl)-1,3-dihydro-2H-1,4-benzodiazepin-2-one, nor-Flurazepam, 2H-1,4-Benzodiazepin-2-one, 7-chloro-5-(o-fluorophenyl)-1,3-dihydro-, 7-Chloro-5-(2-fluoro-phenyl)-1,3-dihydro-2H-1,4-benzodiazepin-2-one, Opera_ID_747, 7-chloro-1,3-dihydro-5-(2-fluorophenyl)-2H-1,4-benzodiazepin-2-one

Safety & hazard information (GHS)

Harmful / irritant

Signal word: Warning

Hazard statements

H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
H336May cause drowsiness or dizziness

Precautionary statements: P261, P264, P264 + P265, P270, P271, P280, P301 + P317, P302 + P352, P304 + P340, P305 + P351 + P338, P319, P321, P330, P332 + P317, P337 + P317, P362 + P364, P403 + P233, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Midazolam EP Impurity F?

The CAS Registry Number of Midazolam EP Impurity F is 2886-65-9. It is also known as Flurazepam EP Impurity B, Flurazepam - Impurity B, Midazolam - Impurity F.

What is the molecular formula and molecular weight of Midazolam EP Impurity F?

Midazolam EP Impurity F has the molecular formula C15H10ClFN2O and a molecular weight of 288.7 g/mol. Its IUPAC name is 7-chloro-5-(2-fluorophenyl)-1,3-dihydro-1,4-benzodiazepin-2-one.

What is Midazolam EP Impurity F used for?

Midazolam EP Impurity F is supplied as a characterised reference material related to Flurazepam. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Midazolam EP Impurity F can I order?

We supply Midazolam EP Impurity F in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Midazolam EP Impurity F?

Yes. Every lot of Midazolam EP Impurity F is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Midazolam EP Impurity F be shipped internationally?

Yes. Midazolam EP Impurity F is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.