4-(Thiophen-2-yl)thiazol-2-amine

About 4-(Thiophen-2-yl)thiazol-2-amine

4-(Thiophen-2-yl)thiazol-2-amine is an impurity of Avatrombopag carrying the CAS registry number 28989-50-6. Formula C7H6N2S2, molecular weight 182.3 g/mol. Its systematic (IUPAC) name is 4-thiophen-2-yl-1,3-thiazol-2-amine. Common synonyms include 4-(2-thienyl)-1,3-thiazol-2-amine and 4-Thiophen-2-yl-thiazol-2-ylamine.

It is supplied as a solid. Keep the vial tightly closed, protected from light and humidity, at the temperature stated on the Certificate of Analysis. The GHS classification uses the signal word “Warning”, so appropriate gloves, eye protection and ventilation are recommended.

This Avatrombopag impurity supports analytical method development and validation (AMV), batch release testing and the impurity sections of ANDA and DMF filings. Buyers come mainly from pharmaceutical manufacturing and academic and industrial research.

Available in 10 mg, 25 mg, 50 mg and 100 mg packs, 4-(Thiophen-2-yl)thiazol-2-amine is dispatched with a Certificate of Analysis (COA) to destinations worldwide.

Typical applications

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Industries

Related to Avatrombopag

View every impurity, metabolite and intermediate we list for Avatrombopag.

Avatrombopag impurities

Specifications & identifiers

Chemical identifiers
Product name	4-(Thiophen-2-yl)thiazol-2-amine
Catalogue No.	VQ-047493
CAS Number	28989-50-6
IUPAC name	4-thiophen-2-yl-1,3-thiazol-2-amine
Molecular formula	C₇H₆N₂S₂
Molecular weight	182.3 g/mol
Exact mass	181.9972
Grade	Reference Standard
HSN code	38229090
InChIKey	XRNPDKQNHIKARG-UHFFFAOYSA-N
SMILES	C1=CSC(=C1)C2=CSC(=N2)N
PubChem CID	243973

Physical properties
Physical form	Solid
LogP (XLogP3)	2
H-bond donors / acceptors	1 / 4
TPSA	95.4 Å²
Synonyms	4-(2-thienyl)-1,3-thiazol-2-amine, 4-Thiophen-2-yl-thiazol-2-ylamine, 4-(thiophen-2-yl)-1,3-thiazol-2-amine, 2-thiazolamine, 4-(2-thienyl)-, 4-(2-Thienyl)thiazol-2-amine, 2-amino-4-(2-thienyl)thiazole, 4-(2-Thienyl)-2-thiazolamine, 4-(2-thienyl)-1,3-thiazol-2(3H)-imine, 4-(2-thienyl)-1,3-thiazole-2-ylamine, 2-(2-Amino-4-thiazolyl)thiophene, 2-amino-4-(thiophen-2-yl)thiazole, 4-(2-thienyl)-1,3-thiazol-2-amine(SALTDATA: FREE)

Safety & hazard information (GHS)

Harmful / irritant

Signal word: Warning

Hazard statements

H302Harmful if swallowed
H319Causes serious eye irritation

Precautionary statements: P264, P264 + P265, P270, P280, P301 + P317, P305 + P351 + P338, P330, P337 + P317, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of 4-(Thiophen-2-yl)thiazol-2-amine?

The CAS Registry Number of 4-(Thiophen-2-yl)thiazol-2-amine is 28989-50-6. It is also known as 4-(2-thienyl)-1,3-thiazol-2-amine, 4-Thiophen-2-yl-thiazol-2-ylamine, 4-(thiophen-2-yl)-1,3-thiazol-2-amine.

What is the molecular formula and molecular weight of 4-(Thiophen-2-yl)thiazol-2-amine?

4-(Thiophen-2-yl)thiazol-2-amine has the molecular formula C7H6N2S2 and a molecular weight of 182.3 g/mol. Its IUPAC name is 4-thiophen-2-yl-1,3-thiazol-2-amine.

What is 4-(Thiophen-2-yl)thiazol-2-amine used for?

4-(Thiophen-2-yl)thiazol-2-amine is supplied as a characterised reference material related to Avatrombopag. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of 4-(Thiophen-2-yl)thiazol-2-amine can I order?

We supply 4-(Thiophen-2-yl)thiazol-2-amine in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with 4-(Thiophen-2-yl)thiazol-2-amine?

Yes. Every lot of 4-(Thiophen-2-yl)thiazol-2-amine is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can 4-(Thiophen-2-yl)thiazol-2-amine be shipped internationally?

Yes. 4-(Thiophen-2-yl)thiazol-2-amine is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.