Cefazolin EP Impurity E

Name: Cefazolin EP Impurity E
Brand: Vaqora Chemicals
SKU: VQ-022063

About Cefazolin EP Impurity E

Cefazolin EP Impurity E (CAS 29490-19-5) is a pharmacopeial impurity of Cefazolin offered by Vaqora Chemicals. The compound has the formula C3H4N2S2, corresponding to a molecular weight of 132.21 g/mol. Systematically, it is named 5-methyl-3H-1,3,4-thiadiazole-2-thione. Common synonyms include Cefazolin Sodium - Impurity E and 5-Methyl-1,3,4-thiadiazole-2-thiol.

The product is provided as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. It carries the GHS signal word “Warning” with 3 hazard statements. Review the Safety Data Sheet before use.

Pharmaceutical QC and development laboratories use this impurity standard of Cefazolin to develop and validate HPLC methods, to set specification limits and to document impurity profiles in ANDA and DMF submissions. Buyers come mainly from pharmaceutical manufacturing and academic and industrial research.

We offer Cefazolin EP Impurity E in 10 mg, 25 mg, 50 mg and 100 mg packs with a batch-specific COA, and ship to customers worldwide.

Typical applications

Pharmacopeial method verification
Impurity profiling
QC release testing
ANDA / DMF filings

Industries

Related to Cefazolin

View every impurity, metabolite and intermediate we list for Cefazolin.

Cefazolin impurities

Grade guides

Specifications & identifiers

Chemical identifiers
Product name	Cefazolin EP Impurity E
Catalogue No.	VQ-022063
CAS Number	29490-19-5
IUPAC name	5-methyl-3H-1,3,4-thiadiazole-2-thione
Molecular formula	C₃H₄N₂S₂
Molecular weight	132.21 g/mol
Exact mass	131.9816
Grade	Reference Standard
HSN code	38229090
InChIKey	FPVUWZFFEGYCGB-UHFFFAOYSA-N
SMILES	CC1=NNC(=S)S1
PubChem CID	1810203

Physical properties
Physical form	Solid
LogP (XLogP3)	0.9
H-bond donors / acceptors	1 / 3
TPSA	81.8 Å²
Synonyms	Cefazolin Sodium - Impurity E, 5-Methyl-1,3,4-thiadiazole-2-thiol, 2-Mercapto-5-methyl-1,3,4-thiadiazole, 5-Methyl-1,3,4-thiadiazole-2(3H)-thione, 2-Methyl-5-mercapto-1,3,4-thiadiazole, 5-methyl-1,3,4-thiadiazolyl-2-thiol, 2-Methyl-1,3,4-thiadiazoline-5-thione, 1,3,4-Thiadiazole-2(3H)-thione, 5-methyl-, 5-methyl-1,3,4-thiadiazol-2-thiol, 5-methyl-2,3-dihydro-1,3,4-thiadiazole-2-thione, 5-Methyl-1,3,4-thiadiazol-2-thiol (MMTD), 5-mercapto-2-methyl-1,3,4-thiadiazole

Safety & hazard information (GHS)

Harmful / irritant

Signal word: Warning

Hazard statements

H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation

Precautionary statements: P261, P264, P264 + P265, P271, P280, P302 + P352, P304 + P340, P305 + P351 + P338, P319, P321, P332 + P317, P337 + P317, P362 + P364, P403 + P233, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Cefazolin EP Impurity E?

The CAS Registry Number of Cefazolin EP Impurity E is 29490-19-5. It is also known as Cefazolin Sodium - Impurity E, 5-Methyl-1,3,4-thiadiazole-2-thiol, 2-Mercapto-5-methyl-1,3,4-thiadiazole.

What is the molecular formula and molecular weight of Cefazolin EP Impurity E?

Cefazolin EP Impurity E has the molecular formula C3H4N2S2 and a molecular weight of 132.21 g/mol. Its IUPAC name is 5-methyl-3H-1,3,4-thiadiazole-2-thione.

What is Cefazolin EP Impurity E used for?

Cefazolin EP Impurity E is supplied as a characterised reference material related to Cefazolin. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Cefazolin EP Impurity E can I order?

We supply Cefazolin EP Impurity E in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Cefazolin EP Impurity E?

Yes. Every lot of Cefazolin EP Impurity E is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Cefazolin EP Impurity E be shipped internationally?

Yes. Cefazolin EP Impurity E is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.